Substance P modulates NMDA responses and causes long-term protein synthesis-dependent modulation of the lamprey locomotor network

Journal of Neuroscience

Volumn 18, Issue 12, 1998, Pages 4800-4813

  Parker, David ^a   Zhang, Weiqi ^a   Grillner, Sten ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dopamine; Locomotor network; Neuro modulation; Neuropeptide; Protein synthesis; Substance P

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID; PROTEIN C; SPANTIDE; SUBSTANCE P; TACHYKININ;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; LAMPREY; LOCOMOTION; LONG TERM POTENTIATION; NERVE POTENTIAL; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SPINAL CORD;

EID: 0032526973     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-12-04800.1998     Document Type: Article

References (52)

1. 2+ chelators attenuate neurotransmitter release at the squid giant synapse. J Neurosci 11:1496-1507.
2. Alford S, Grillner S (1990) CNQX and DNQX block non-NMDA synaptic transmission but not NMDA-evoked locomotion in lamprey spinal cord. Brain Res 506:297-302.
3. Barthe J-Y, Clarac F (1997) Modulation of the spinal network for locomotion by substance P in the neonatal rat. Exp Brain Res 115:485-492.
4. Ben Ari Y, Aniksztejn L, Bregestovski P (1992) Protein kinase C modulation of NMDA currents: an important link for LTP induction. Trends Neurosci 15:333-339.
5. Bliss TVP, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39.
6. Bergold PJ, Sweatt JD, Winicov I, Weiss KR. Kandel ER, Schwartz JH (1990) Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase. Proc Natl Acad Sci USA 87:3788-3791.
7. Brodin L, Grillner S (1985) The role of putative excitatory amino acid neurotransmitters in the initiation of locomotion in the lamprey spinal cord. 1. The effects of excitatory amino acid antagonists. Brain Res 360:139-148.
8. Brodin L, Grillner S (1986) Effects of magnesium on fictive locomotion induced by activation of N-methyl-D-aspartate (NMDA) receptors in the lamprey spinal cord in vitro. Brain Res 380:244-252.
9. Brodin L, Grillner S (1990) The lamprey CNS in vitro: an experimentally amenable model for synaptic transmission and integrative functions. In: Preparations of vertebrate central nervous system in vitro (Jahnsen H, ed), pp 103-153. New York: Wiley.
10. Brodin L, Grillner S, Rovainen C (1985) N-methyl-D-aspartate (NMDA), kainate and quisqualate receptors and the generation of fictive locomotion in the lamprey spinal cord. Brain Res 325:302-306.
11. Buchanan JT (1993) Electrophysiological properties of identified classes of lamprey spinal neurons. J Neurophysiol 70:2313-2325.
12. Buchanan JT (1996) Lamprey spinal interneurons and their roles in swimming activity. Brain Behav Evol 48:287-296.
13. Byrne JH, Kandel ER (1996) Presynaptic facilitation revisited: state and time-dependence. J Neurosci 16:425-435.
14. Chen L, Huang L-YM (1992) Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature 356:521-523.
15. Dale N, Kandel ER, Schacher S (1987) Serotonin produces long-term changes in the excitability of Aplysia sensory neurons in culture that depend on protein synthesis. J Neurosci 7:2232-2238.
16. Duggan AW (1995) Release of neuropeptides in the spinal cord. Prog Brain Res 104:197-224.
17. El Manira A, Zhang W, Svensson E, Bussieres N (1997) 5-HT inhibits calcium current and synaptic transmission from sensory neurons in lamprey. J Neurosci 17:1786-1794.
18. Fazeli MS, Corbett J, Dunn MJ, Dolphin AC, Bliss TC (1993) Changes in protein synthesis accompanying long-term potentiation in the dentate gyrus in vivo. J Neurosci 13:1346-1353.
19. Freeman FM, Rose SPR, Scholey AB (1995) Two time windows of anisomycin-induced amnesia for passive avoidance training in the day-old chick. Neurobiol Learn Mem 63:291-295.
20. Gerber G, Kangrga I, Ryu, PD Larew A, Randic M (1992) Multiple effects of phorbol esters in the rat spinal dorsal horn. J Neurosci 9:3606-3617.
21. Greenberg SM, Castellucci VF, Bayley H, Schwartz JH (1987) A molecular mechanism for long-term sensitisation in Aplysia. Nature 329:62-65.
22. Grillner P, Hill RH, Grillner S (1991) 7-chlorokynurenic acid blocks NMDA receptor-induced fictive locomotion in lamprey-evidence for a physiological role of the glycine site. Acta Physiol Scand 141:131-132.
23. Grillner S, EI Manira A, Tegner J, Wadden T, Vinat L, Barthe J-Y (1994) Dynamic changes in functional connectivity in a lower vertebrate model. In: Cellular and molecular mechanisms underlying higher neural function (Selverston AJ, Asher P, eds), pp 127-147, New York: Wiley.
24. Grillner S, Deliagina T, Ekeberg Ö, El Manira A, Hill RH, Lansner A, Orlovsky GN, Wallen P (1995) Neuronal networks that co-ordinate locomotion and body orientation in lamprey. Trends Neurosci 18:270-279.
25. Hardisty MW, Potter IC (1983) The biology of lampreys. London: Academic.
26. Harris-Warrick RM, Cohen AH (1985) Serotonin modulates the central pattern generator for locomotion in the isolated lamprey spinal cord. J Exp Biol 116:27-46.
27. Harris-Warrick RM, Marder E, Selverston AI, Moulins M (1992) Dynamic biological networks. Cambridge, MA: MIT.
28. 2+ buffers on evoked release and on facilitation in the crayfish neuromuscular junction. Neurosci Lett 125:215-218.
29. Johnson JW, Ascher P (1986) Glycine potentiates the NMDA response of mouse central neurones. Nature 325:529-531.
30. 3H]eticlopride in the rat brain: evidence for selective labelling of dopamine receptors. Eur J Pharmacol 120:217-226.
31. Levine JD, Fields HL, Basbaum AI (1993) Peptides and the primary afferent nociceptor. J Neurosci 13:2273-2286.
32. Mayer ML, Westbrook G (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog Neurobiol 28:197-276.
33. Mayer ML, Westbrook GL, Guthrie AS (1984) Voltage dependent block by magnesium of NMDA responses in spinal cord neurones. Nature 309:261-263.
34. McClellan A, Grillner S (1984) Activation of fictive swimming by electrical stimulation of "locomotor regions" in the brainstem of the lamprey. Brain Res 300:357-361.
35. McPherson DR, Kemnitz CP (1994) Modulation of fictive swimming and motoneuron physiology by dopamine, and its immunocytochemical localization in the spinal cord. Neurosci Lett 166:23-26.
36. Montarolo PG, Goelet P, Castellucci VF, Morgan J, Kandel ER, Schacher S (1986) A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Apiysia. Science 234:1249-1254.
37. 2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience 75:99-109.
38. Parker DJ, Grillner S (1996) Tachykinin-mediated modulation of sensory neurons, interneurons, and synaptic transmission in the lamprey spinal cord. J Neurophysiol 76:4031-4039.
39. Parker DJ, Grillner S (1998) Long-term modulation of spinal locomotor circuits in the lamprey. Göttingen Neurobiology Meeting abstract, March, 1998.
40. Parker DJ, Svensson E, Grillner S (1997) Substance P modulates mechanosensory afferents in the lamprey via a protein kinase C-mediated reduction of potassium conductances. Eur J Neurosci 9:2064-2076.
41. Rose SPR (1991) How chicks make memories: the cellular cascade from c-fos to dendritic remodelling. Trends Neurosci 14:390-397.
42. Rusin KI, Ryu PD, Randic M (1992) Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins. J Neurophysiol 68:265-286.
43. Schotland J, Shupliakov O, Wikström M, Brodin L, Srinivasan M, You Z, Herrera-Marschitz M, Zhang W, HökfeltT, Grillner S (1995) Control of lamprey locomotor neurons by colocalized monoamine transmitters. Nature 374:266-268.
44. Schotland JL, Shupliakov O, Grillner S, Brodin L (1996) synaptic and non-synaptic monoaminergic neuron systems in the lamprey spinal cord. J Comp Neurol 372:229-244.
45. Thomas KL, Laroche S, Errington ML, Bliss TVP, Hunt SP (1994) Spatial and temporal changes in signal transduction pathways during LTP. Neuron 13:737-745.
46. Van Dongen P, Hokfelt T, Grillner S, Verhofsted AAJ, Steinbush HWM, Cuello AC, Terenius L (1985) Immunohistochemical demonstration of some putative neurotransmitters in the lamprey spinal cord and spinal ganglia: 5-hydroxytryptamine, tachykinin. and neuropeptide Y immunoreactive neurons and fibers. J Comp Neurol 234:501-522.
47. Van Dongen P, Theodorsson-Norheim E, Brodin E, Hökfelt T, Grillner S, Peters A, Cuello AC, Forssman WG, Reinecke M, Singer EA, Lazarus LH (1986) Immunohistochemical and Chromatographic studies of peptides with tachykinin-like immunoreactivity in the central nervous system of the lamprey. Peptides 7:297-313.
48. Wallen P, Grillner S (1987) N-methyl-D-aspartate receptor-induced inherent oscillatory activity in neurons active during locomotion in the lamprey. J Neurosci 7:2745-2755.
49. Wallen P, Buchanan JT, Grillner S, Hill RH, Christenson J, Hokfelt T (1989) Effects of 5-hydroxytryptamine on the afterhyperpolarisation, spike frequency regulation and oscillatory membrane properties in lamprey spinal cord nerves. J Neurophysiol 61:759-768.
50. Waugh D, Bondareva V, Rusakov, Bjenning CY, Nielson PF, Conlon JM (1995) Tachykinins with unusual structural features from a urodele, the amphiuma, an elasmobranch, the hammerhead shark, and an agnathan, the river lamprey. Peptides 16:615-621.
51. White SR (1985) A comparison of the effects of serotonin, substance P, and thyrotrophin releasing hormone on the excitability of rat spinal motor neurones in vivo. Brain Res 335:63-70.
52. Yanagisawa M, Hosaki R, Otsuka M (1992) The isolated spinal cordskin preparation of the newborn rat and the effects of some allogenic and analgesic substances. Eur J Pharmacol 220:111-117.