메뉴 건너뛰기




Volumn 90, Issue 6, 1998, Pages 259-270

A potent 5-hydroxytryptamine receptor (5-HT(2A)) antagonist, DV-7028, delays arterial thrombosis development in rats

Author keywords

5 HT(2A) receptor; Arterial and venous thrombosis; DV 7028

Indexed keywords

3 [2 [4 (4 FLUOROBENZOYL)PIPERIDIN 1 YL]ETHYL] 6,7,8,9 TETRAHYDRO 2H PYRIDO[1,2 A] 1,3,5 TRIAZINE 2,4(3H) DIONE; ANTICOAGULANT AGENT; SEROTONIN 2A ANTAGONIST; UNCLASSIFIED DRUG;

EID: 0032526822     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(98)00037-1     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0020565085 scopus 로고
    • 5-hydroxytryptamine and platelet aggregation
    • De Clerck F., Herman A.G. 5-hydroxytryptamine and platelet aggregation. Fed Proc. 42:1983;228-232.
    • (1983) Fed Proc , vol.42 , pp. 228-232
    • De Clerck, F.1    Herman, A.G.2
  • 4
    • 0028013308 scopus 로고
    • 2 receptor antagonist, on ischemic cerebral blood flow and infarct volume in rat middle cerebral artery occlusion
    • 2 receptor antagonist, on ischemic cerebral blood flow and infarct volume in rat middle cerebral artery occlusion. Stroke. 25:1994;481-486.
    • (1994) Stroke , vol.25 , pp. 481-486
    • Takagi, K.1    Ginsberg, M.D.2    Globus, M.Y.3    Bustro, R.4    Dietrich, W.D.5
  • 6
    • 0024592493 scopus 로고
    • Prevention of atherosclerotic complications with ketanserin
    • Verstraete M. Prevention of atherosclerotic complications with ketanserin. Br Med J. 298:1989;424-429.
    • (1989) Br Med J , vol.298 , pp. 424-429
    • Verstraete, M.1
  • 7
    • 0019996644 scopus 로고
    • Mechanism of hypotensive effect of ketanserin
    • Fozard R.F. Mechanism of hypotensive effect of ketanserin. J Cardiovasc Pharmacol. 4:1982;829-838.
    • (1982) J Cardiovasc Pharmacol , vol.4 , pp. 829-838
    • Fozard, R.F.1
  • 9
    • 0015827954 scopus 로고
    • Introduction of experimental arterial occlusive thrombi in rats
    • Hornsta G., Vandelmans-Starrengurg A. Introduction of experimental arterial occlusive thrombi in rats. Atherosclerosis. 17:1973;369-382.
    • (1973) Atherosclerosis , vol.17 , pp. 369-382
    • Hornsta, G.1    Vandelmans-Starrengurg, A.2
  • 10
    • 0018962983 scopus 로고
    • Failure of aspirin at different doses to modify experimental thrombosis in rats
    • Reyers I., Mussoni L., Donati M.B., de Gaetano G. Failure of aspirin at different doses to modify experimental thrombosis in rats. Thromb Res. 18:1980;669-674.
    • (1980) Thromb Res , vol.18 , pp. 669-674
    • Reyers, I.1    Mussoni, L.2    Donati, M.B.3    De Gaetano, G.4
  • 11
    • 0019982226 scopus 로고
    • Bleeding time in rats: A comparison of different experimental conditions
    • Dejana E., Villa S., De Gaetano G. Bleeding time in rats. A comparison of different experimental conditions Thromb Haemost. 48:1991;108-111.
    • (1991) Thromb Haemost , vol.48 , pp. 108-111
    • Dejana, E.1    Villa, S.2    De Gaetano, G.3
  • 13
    • 78651139188 scopus 로고
    • The aggregation of blood platelets
    • Born G.V., Cross M.J. The aggregation of blood platelets. J Physiol. 168:1963;178-195.
    • (1963) J Physiol , vol.168 , pp. 178-195
    • Born, G.V.1    Cross, M.J.2
  • 14
    • 0022388107 scopus 로고
    • Influence of alpha- And beta-adrenoceptors on thrombin-induced serotonin release in rat platelets
    • Koutouzov S., Cothenet-Vernoux L., Marche P., Dausse J.P. Influence of alpha- and beta-adrenoceptors on thrombin-induced serotonin release in rat platelets. Thromb Res. 40:1985;147-159.
    • (1985) Thromb Res , vol.40 , pp. 147-159
    • Koutouzov, S.1    Cothenet-Vernoux, L.2    Marche, P.3    Dausse, J.P.4
  • 15
    • 0014638942 scopus 로고
    • A perfused tail artery preparation from the rat
    • Nicholas T. A perfused tail artery preparation from the rat. J Pharm Pharmacol. 21:1969;826-832.
    • (1969) J Pharm Pharmacol , vol.21 , pp. 826-832
    • Nicholas, T.1
  • 16
    • 73649209211 scopus 로고
    • Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters
    • Van Rossum J.M., Hurkman J.A., Wolters C.J.J. Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. Arch Int Pharmacodyn Ther. 143:1963;299-331.
    • (1963) Arch Int Pharmacodyn Ther , vol.143 , pp. 299-331
    • Van Rossum, J.M.1    Hurkman, J.A.2    Wolters, C.J.J.3
  • 18
    • 0019123929 scopus 로고
    • The role of platelets in acute vascular events
    • Harker L.A., Ritchie J.L. The role of platelets in acute vascular events. Circulation. 62:1980;V13-V19.
    • (1980) Circulation , vol.62
    • Harker, L.A.1    Ritchie, J.L.2
  • 19
    • 0022981606 scopus 로고
    • Role of platelet activation and fibrin formation in thrombogenesis
    • Vermylen J., Verstraete M., Fuster V. Role of platelet activation and fibrin formation in thrombogenesis. J Am Coll Cardiol. 8:1986;2B-9B.
    • (1986) J Am Coll Cardiol , vol.8
    • Vermylen, J.1    Verstraete, M.2    Fuster, V.3
  • 21
    • 0023119154 scopus 로고
    • Effect of the serotonin antagonists, cyproheptadine, ketanserin and mianserin, on cyclic flow reductions in stenosed canine coronary arteries
    • Bush L.R. Effect of the serotonin antagonists, cyproheptadine, ketanserin and mianserin, on cyclic flow reductions in stenosed canine coronary arteries. J Pharmacol Exp Ther. 240:1987;674-682.
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 674-682
    • Bush, L.R.1
  • 22
    • 0018747917 scopus 로고
    • Prevention of blockade of partially obstructed coronary arteries with prostacyclin correlated with inhibition of platelet aggregation
    • Aiken J.W., Goram R.R., Shebusli R.J. Prevention of blockade of partially obstructed coronary arteries with prostacyclin correlated with inhibition of platelet aggregation. Prostaglandins. 17:1979;483-494.
    • (1979) Prostaglandins , vol.17 , pp. 483-494
    • Aiken, J.W.1    Goram, R.R.2    Shebusli, R.J.3
  • 23
    • 0020039061 scopus 로고
    • Blood flow reduction in stenosed canine coronary arteries: Vasospasm or platelet aggregation?
    • Folts J.D., Gallagher K.B., Rowe G.G. Blood flow reduction in stenosed canine coronary arteries. Vasospasm or platelet aggregation? Circulation. 65:1982;248-254.
    • (1982) Circulation , vol.65 , pp. 248-254
    • Folts, J.D.1    Gallagher, K.B.2    Rowe, G.G.3
  • 24
    • 0021136471 scopus 로고
    • Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries
    • Bush L.R., Campbell W.B., Buja L.M., Tilton G.F., Willerson J.T. Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries. Circulation. 69:1984;1161-1170.
    • (1984) Circulation , vol.69 , pp. 1161-1170
    • Bush, L.R.1    Campbell, W.B.2    Buja, L.M.3    Tilton, G.F.4    Willerson, J.T.5
  • 25
    • 0022272781 scopus 로고
    • Pharmacological analysis of factors influencing platelet aggregation in stenosed coronary arteries of dogs
    • Aiken J.W. Pharmacological analysis of factors influencing platelet aggregation in stenosed coronary arteries of dogs. Ann N Y Acad Sci. 454:1985;131-134.
    • (1985) Ann N Y Acad Sci , vol.454 , pp. 131-134
    • Aiken, J.W.1
  • 26
    • 0023787916 scopus 로고
    • Effect of thromboxane and serotonin receptor antagonists on intracoronary platelet deposition in dogs with experimentally stenosed coronary arteries
    • Golino P., Buja L.M., Ashton J.H., Kulkarini P., Taylor A., Willerson J.T. Effect of thromboxane and serotonin receptor antagonists on intracoronary platelet deposition in dogs with experimentally stenosed coronary arteries. Circulation. 78:1988;701-711.
    • (1988) Circulation , vol.78 , pp. 701-711
    • Golino, P.1    Buja, L.M.2    Ashton, J.H.3    Kulkarini, P.4    Taylor, A.5    Willerson, J.T.6
  • 29
    • 84941326567 scopus 로고
    • Formation of thrombus and thrombolysis in animal experiments
    • Martin M. Formation of thrombus and thrombolysis in animal experiments. Angiologica. 5:1968;80-94.
    • (1968) Angiologica , vol.5 , pp. 80-94
    • Martin, M.1
  • 30
    • 0025824073 scopus 로고
    • Antithrombotic effect of MCI-9042, a new antiplatelet agent on experimental thrombosis models
    • Hara H., Kitajima A., Shimada H., Tamao Y. Antithrombotic effect of MCI-9042, a new antiplatelet agent on experimental thrombosis models. Thromb Haemost. 66:1991;484-488.
    • (1991) Thromb Haemost , vol.66 , pp. 484-488
    • Hara, H.1    Kitajima, A.2    Shimada, H.3    Tamao, Y.4
  • 31
    • 0021981360 scopus 로고
    • Antithrombotic effect of ticlopidine in a platelet-independent model of venous thrombosis
    • Bernat A., Vallée E., Maffrand J.P., Roncucci R. Antithrombotic effect of ticlopidine in a platelet-independent model of venous thrombosis. Thromb Res. 37:1985;279-285.
    • (1985) Thromb Res , vol.37 , pp. 279-285
    • Bernat, A.1    Vallée, E.2    Maffrand, J.P.3    Roncucci, R.4
  • 32
    • 0023738061 scopus 로고
    • The role of platelets and in ADP experimental thrombosis induced by venous stasis in the rat
    • Bernat A., Vallee E., Maffrand J.P., Gordon J.L. The role of platelets and in ADP experimental thrombosis induced by venous stasis in the rat. Thromb Res. 52:1988;65-70.
    • (1988) Thromb Res , vol.52 , pp. 65-70
    • Bernat, A.1    Vallee, E.2    Maffrand, J.P.3    Gordon, J.L.4
  • 33
    • 0022577767 scopus 로고
    • Effect of ketanserin a selective 5-hydroxytryptamine-2 serotonergic antagonist on the secondary recruitment of human platelets in vitro
    • De Clerck F., Xhonneux B. Effect of ketanserin a selective 5-hydroxytryptamine-2 serotonergic antagonist on the secondary recruitment of human platelets in vitro. Agents Actions. 17:1986;515-526.
    • (1986) Agents Actions , vol.17 , pp. 515-526
    • De Clerck, F.1    Xhonneux, B.2
  • 35
    • 0020538735 scopus 로고
    • Effect of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets
    • Bevan J., Heptinstall S. Effect of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets. Thromb Res. 30:1983;415-423.
    • (1983) Thromb Res , vol.30 , pp. 415-423
    • Bevan, J.1    Heptinstall, S.2
  • 36
    • 0009968436 scopus 로고
    • Membrane active drugs and the aggregation of human platelets
    • Mills D.C.B., Roberts G.C.K. Membrane active drugs and the aggregation of human platelets. Nature. 213:1967;35-38.
    • (1967) Nature , vol.213 , pp. 35-38
    • Mills, D.C.B.1    Roberts, G.C.K.2
  • 37
    • 0018756126 scopus 로고
    • Shape change and uptake of 5-hydroxytryptamine in human blood platelets
    • Laubscher A., Pletscher A. Shape change and uptake of 5-hydroxytryptamine in human blood platelets. Life Sci. 24:1979;1833-1840.
    • (1979) Life Sci , vol.24 , pp. 1833-1840
    • Laubscher, A.1    Pletscher, A.2
  • 38
    • 0022704136 scopus 로고
    • Vascular interactions of serotonin and norepinephrine in renal hypertensive rabbits
    • Pott J.W.R., Moreland R.S., Gantzos R.D., Babcock C., Bohr D.F. Vascular interactions of serotonin and norepinephrine in renal hypertensive rabbits. J Hypertens. 4:1986;207-213.
    • (1986) J Hypertens , vol.4 , pp. 207-213
    • Pott, J.W.R.1    Moreland, R.S.2    Gantzos, R.D.3    Babcock, C.4    Bohr, D.F.5
  • 41
    • 0021159474 scopus 로고
    • Prolongation of the tail bleeding time by ketanserin: Mechanism of action
    • Buczko W., Gambino M.C., De Gaetano G. Prolongation of the tail bleeding time by ketanserin. mechanism of action Eur J Pharmacol. 103:1984;261-268.
    • (1984) Eur J Pharmacol , vol.103 , pp. 261-268
    • Buczko, W.1    Gambino, M.C.2    De Gaetano, G.3
  • 42
    • 0021674879 scopus 로고
    • Platelet wall interactions in hemostasis: Implication of 5-hydroxytryptamine
    • De Clerck F., Somers Y., Van Grop L. Platelet wall interactions in hemostasis. Implication of 5-hydroxytryptamine Agents Actions. 15:1984;627-637.
    • (1984) Agents Actions , vol.15 , pp. 627-637
    • De Clerck, F.1    Somers, Y.2    Van Grop, L.3
  • 43
    • 0019916099 scopus 로고
    • Platelet-mediated vascular contractions: Inhibition of the serotonergic component by ketanserin
    • De Clerck F., Van Nueten J.M. Platelet-mediated vascular contractions. Inhibition of the serotonergic component by ketanserin Thromb Res. 27:1982;713-727.
    • (1982) Thromb Res , vol.27 , pp. 713-727
    • De Clerck, F.1    Van Nueten, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.