Chromogranin B (secretogranin I), a neuroendocrine-regulated secretory protein, is sorted to exocrine secretory granules in transgenic mice

EMBO Journal

Volumn 17, Issue 12, 1998, Pages 3277-3289

  Natori, Shoichi ^a,b   King, Angus ^a,c   Hellwig, Andrea ^a   Weiß, Ursula ^a   Iguchi, Haruo ^d   Tsuchiya, Benio ^e   Kameya, Toru ^f   Takayanagi, Ryoichi ^g   Nawata, Hajime ^g   Huttner, Wieland B ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b ASO IIZUKA HOSPITAL   (Japan)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d NATIONAL KYUSHU CANCER CENTER   (Japan)

^e KITASATO UNIVERSITY   (Japan)

^f KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^g KYUSHU UNIVERSITY   (Japan)

Author keywords

Exocrine pancreas; Granins; Protein sorting; Secretory granules; Transgenic mice

Indexed keywords

AMYLASE; CHROMOGRANIN B; MATRIX PROTEIN; SECRETORY PROTEIN; ZYMOGEN GRANULE;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FRACTIONATION; CELL VACUOLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCRINE CELL; GOLGI COMPLEX; HUMAN CYTOMEGALOVIRUS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MOUSE; NERVE CELL; NEUROSECRETORY CELL; NONHUMAN; NORTHERN BLOTTING; PANCREAS; PH; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SECRETORY GRANULE; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALS; CHROMOGRANIN B; CHROMOGRANINS; CYTOPLASMIC GRANULES; ENDOCRINE SYSTEM; ENZYME PRECURSORS; EXOCRINE GLANDS; GOLGI APPARATUS; HYDROGEN-ION CONCENTRATION; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PANCREAS; TRANSGENES; VACUOLES;

ANIMALIA; HUMAN HERPESVIRUS 5; MUS MUSCULUS;

EID: 0032526709     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.12.3277     Document Type: Article

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