GalNAc-α-O-benzyl inhibits NeuAcα2-3 glycosylation and blocks the intracellular transport of apical glycoproteins and mucus in differentiated HT-29 cells

Journal of Cell Biology

Volumn 141, Issue 6, 1998, Pages 1311-1322

  Huet, Guillemette ^a   Hennebicq Reig, Sylviane ^a   De Bolos, Carmen ^b   Ulloa, Fausto ^b   Lesuffleur, Thécla ^a   Barbat, Alain ^a   Carrière, Véronique ^a   Kim, Isabelle ^b   Real, Francisco X ^b   Delannoy, Philippe ^c   Zweibaum, Alain ^a  

^a INSERM   (France)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYL 2 ACETAMIDO 2 DEOXY ALPHA GALACTOPYRANOSIDE; CARCINOEMBRYONIC ANTIGEN; DIPEPTIDYL PEPTIDASE IV; GLYCOPROTEIN; GLYCOPROTEIN GP 120; MUCIN; N ACETYLGALACTOSAMINE; SIALYLTRANSFERASE; UNCLASSIFIED DRUG;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CANCER CELL CULTURE; CELL DIFFERENTIATION; COLON CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTESTINE BRUSH BORDER; INTESTINE CELL; INTRACELLULAR TRANSPORT; MUCUS SECRETION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN TARGETING; SIALYLATION;

ACETYLGALACTOSAMINE; BENZYL COMPOUNDS; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPROTEINS; GLYCOSYLATION; GOLGI APPARATUS; HT29 CELLS; HUMANS; MICROVILLI; MUCINS; MUCUS; N-ACETYLNEURAMINIC ACID; NEURAMINIC ACIDS; OLIGOSACCHARIDES;

EID: 0032526691     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.141.6.1311     Document Type: Article

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