Structural and functional analysis of J chain-deficient IgM

Journal of Immunology

Volumn 160, Issue 12, 1998, Pages 5979-5989

  Wiersma, Erik J ^a   Collins, Cathy ^a   Fazel, Shafie ^a   Shulman, Marc J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; COMPLEMENT ACTIVATION; CYTOPATHOGENIC EFFECT; HYBRIDOMA; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; DISULFIDES; IMMUNOGLOBULIN J-CHAINS; IMMUNOGLOBULIN M; MICE; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0032526642     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Koshland, M. E. 1985. The coming of age of the immunoglobulin J chain. Annu. Rev. Immunol. 3:425.
2. Brandtzaeg, P. 1985. Role of J chain and secretory component in receptor-mediated glandular and hepatic transport of immunoglobulins in man. Scand. J. Immunol. 22:111.
3. Davis, A. C., and M. J. Shulman. 1989. IgM: molecular requirements for its assembly and function. Immunol. Today 10:118.
4. Wiersma, E. J., and M. J. Shulman. 1995. Assembly of IgM. Role of disulfide bonding and noncovalent interactions. J. Immunol. 154:5265.
5. Brewer, J. W., and R. B. Corley. 1997. Late events in assembly determine the polymeric structure and biological activity of secretory IgM. Mol. Immunol. 34:323.
6. Frutiger, S., G. J. Hughes, N. Paquet, R. Lüthy, and J. Jaton. 1992. Disulfide bond assignment in human J chain and its covalent pairing with immunoglobulin M. Biochemistry 31:12643.
7. Mestecky, J., and R. E. Schrohenloher. 1974. Site of attachment of J chain to human immunoglobulin M. Nature 249:650.
8. Mihaesco, C., E. Mihaesco, and H. Metzger. 1973. Variable J-chain content in human IgM. FEBS Lett. 37:303.
9. Chapuis, R. M., and M. E. Koshland. 1974. Mechanism of IgM polymerization. Proc. Natl. Acad. Sci. USA 71:657.
10. Stott, D. I. 1976. Biosynthesis and assembly of IgM: addition of J chain to intracellular pools of 8S and 19S IgM. Immunochemistry 13:157.
11. Brandtzaeg, P., and H. Prydz. 1984. Direct evidence for an integrated function of J chain and secretory component in epithelial transport of immunoglobulins. Nature 311:71.
12. Hendrickson, B. A., D. A. Conner, D. J. Ladd, D. Kendall, J. E. Casanova, B. Corthesy, E. E. Max, M. R. Neutra, C. E. Seidman, and J. G. Seidman. 1995. Altered hepatic transport of immunoglobulin A in mice lacking the J chain. J. Exp. Med. 182:1905.
13. Natvig, I. B., F. Johansen, T. W. Nordeng, G. Haraldsen, and P. Brandzaeg. 1997. Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM. J. Immunol. 159:4330.
14. Niles, M. J., L. Matsuuchi, and M. E. Koshland. 1995. Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis. Proc. Natl. Acad. Sci. USA 92:2884.
15. Randall, T. D., J. W. Brewer, and R. B. Corley. 1992. Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells. J. Biol. Chem. 267:18002.
16. Cattaneo, A., and M. S. Neuberger. 1987. Polymeric immunoglobulin M is secreted by transfectants of non-lymphoid cells in the absence of immunoglobulin J chain. EMBO J. 6:2753.
17. Davis, A.C., K. H. Roux, and M. J. Shulman. 1988. On the structure of polymeric IgM. Eur. J. Immunol. 18:1001.
18. Randall, T. D., L. B. King, and R. B. Corley. 1990. The biological effects of IgM hexamer formation. Eur. J. Immunol. 20:1971.
19. Davis, A. C., K. H. Roux, J. Pursey, and M. J. Shulman. 1989. Intermolecular disulfide bonding in IgM: effects of replacing cysteine residues in the μ heavy chain. EMBO J. 8:2519.
20. Fazel, S., E. J. Wiersma, and M. J. Shulman. 1997. Interplay of J chain and disulfide bonding in assembly of polymeric IgM. Int. Immunol. 9:1149.
21. Köhler, G., M. J. Potash, H. Lehrach, and M. J. Shulman. 1982. Deletions in immunoglobulin mu chains. EMBO J. 1:555.
22. Connor, A., C. Collins, L. Jiang, M. McMaster, and M. J. Shulman. 1993. Isolation of new nonsense and frameshift mutants in the Immunoglobulin μ heavychain gene of hybridoma cells. Somatic Cell Mol. Genet. 19:313.
23. Baumann, B., M. J. Potash, and G. Kohler. 1985. Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse. EMBO J. 4:351.
24. Rinfret, A., C. Horne, H. Boux, A. Marks, K. J. Dorrington, and M. Klein. 1990. Isotype modulation of idiotypic expression in recombinant isotypic variants of MOPC 315. J. Immunol. 145:925.
25. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
26. Reisfeld, R. A., and P. A. Small. 1966. Electrophoretic heterogeneity of polypeptide chains of specific antibodies. Science 152:1253.
27. Wiersma, E. J., F. Chen, R. Bazin, C. Collins, R. H. Painter, R. Lemieux, and M. J. Shulman. 1997. Analysis of IgM structures involved in J chain incorporation. J. Immunol. 158:1719.
28. Köhler, G., and M. J. Shulman. 1980. Immunoglobulin M mutants. Eur. J. Immunol. 10:467.
29. Roth, R. A., and M. E. Koshland. 1981. Identification of a lymphocyte enzyme that catalyzes pentamer Immunoglobulin M assembly. J. Biol. Chem. 256:4633.
30. Milstein, C. P., N. E. Richardson, E. V. Deverson, and A. Feinstein. 1975. Interchain disulfide bridges of mouse immunoglobulin M. Biochem. J. 151:615.
31. Beale, D., and A. Feinstein. 1969. Studies on the reduction of a human 19 s immunoglobulin M. Biochem. J. 112:187.
32. Krugmann, S., R. J. Pleass, J. D. Atkin, and J. M. Woof. 1997. Structural requirements for assembly of dimeric IgA probed by site-directed mutagenesis of J chain and a cysteine residue of the a chain CH2 domain. J. Immunol. 159:244.
33. Poon, P. H., M. L. Phillips, and V. N. Schumaker. 1985. Immunoglobulin M possesses two binding sites for complement subcomponent C1q, and soluble 1:1 and 2:1 complexes are formed in solution at reduced ionic strength. J. Biol. Chem. 260:9357.
34. Arya, S., F. Chen, S. Spycher, D. E. Isenman, M. J. Shulman, and R. H. Painter. 1994. Mapping of amino acid residues in the Cm3 domain of mouse IgM important in macromolecular assembly an complement-dependent cytolysis. J. Immunol. 152:1206.
35. Feinstein, A., N. Richardson, and M. J. Taussig. 1986. Immunoglobulin flexibility in complement activation. Immunol. Today 7:169.
36. Sørensen, V., I. B. Rasmussen, L. Norderhaug, I. Natvjg, T. E. Michaelsen, and I. Sandlie. 1996. Effect of the IgM and IgA secretory tailpieces on polymerization and secretion of IgM and IgG. J. Immunol. 156:2858.
37. Brewer, J. W., and R. B. Corley. 1996. Quality control in protein biogenesis: thiol-mediated retention monitors the redox state of proteins in the endoplasmatic reticulum. J. Cell Sci. 109:2383.
38. Chintalacharuvu, K. R., M. E. Lamm, and C. S. Kaetzel. 1993. Unstable inter-H chain disulfide bonding and non-covalently associated J chain in rat dimeric IgA. Mol. Immunol 30:19.
39. Crouch, E., A. Persson, D. Chang, and J. Heuser. 1994. Molecular structure of pulmonary surfactant protein D (SP-D). J. Biol. Chem. 269:17311.
40. Slayter, H., J. Loscalzo, P. Bockenstedt, and R. I. Handin. 1985. Native conformation of human von Willebrand protein: analysis by electron microscopy and quasi-elastic light scattering. J. Biol. Chem. 260:8559.
41. Emsley, J., H. E. White, B. P. O'Hara, G. Oliva, N. Srinivasan, I. J. Tickle, T. L. Blundell, M. B. Pepys, and S. P. Wood. 1994. Structure of pentameric human serum amyloid P component. Nature 367:338.
42. Pushko, P., T. Kozlovskaya, I. Sominskaya, A. Brede, E. Stankevica, V. Ose, P. Pumpens, and E. Grens. 1993. Analysis of RNA phage fr coat protein assembly by insertion, deletion and substitution mutagenesis. Protein Eng. 6:883.
43. Petosa, C., R. J. Collier, K. R. Kumpel, S. H. Leppla, and R. C. Liddington. 1997. Crystal structure of the anthrax toxin protective antigen. Nature 385:833.
44. de Haas, F., A. Kuchumov, J. Taveau, N. Boisset, S. N. Vinogradov, and J. N. Lamy. 1997. Three-dimensional reconstruction of native and reassembled Lumbricus terrestris extracellular hemoglobin: localization of the monomeric globin chains. Biochemistry 36:7330.
45. Groll, M., L. Ditzel, J. Lowe, D. Stock, M. Bochtler, H. D. Bartunik, and R. Huber. 1997. Structure of 20S proleasome from yeast a 2.4 Å resolution. Nature 386:463.