Human Hrs, a tyrosine kinase substrate in growth factor-stimulated cells: CDNA cloning and mapping of the gene to chromosome 17

Gene

Volumn 213, Issue 1-2, 1998, Pages 125-132

  Lu, Lingge ^a   Komada, Masayuki ^a   Kitamura, Naomi ^b  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b Department of Life Science   (Japan)

Author keywords

Early endosome; HGF; Scatter factor; Tyrosine phosphorylation; Zinc finger

Indexed keywords

COMPLEMENTARY DNA; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL STIMULATION; CHROMOSOME 17; CONTROLLED STUDY; DNA LIBRARY; GENE MAPPING; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PURIFICATION; SOUTHERN BLOTTING;

ADULT; ANIMALS; BLOTTING, SOUTHERN; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 17; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FETAL PROTEINS; GENE LIBRARY; GENES; HUMANS; HYBRID CELLS; MICE; PHOSPHOPROTEINS; PHOSPHORYLATION; PLACENTA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; RODENTIA; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; ZINC FINGERS;

ANIMALIA; RODENTIA;

EID: 0032526228     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00184-X     Document Type: Article

References (31)

1. Bean A.J., Seifert R., Chen Y.A., Sacks R., Scheller R.H. Hrs-2 is an ATPase implicated in calcium-regulated secretion. Nature. 385:1997;826-829.
2. Bennett M.K., Scheller R.H. A molecular description of synaptic vesicle membrane trafficking. Annu. Rev. Biochem. 63:1994;63-100.
3. Bottaro D.P., Rubin J.S., Faletto D.L., Chan A.M.-L., Kmiecik T.E., Vande Woude G.F., Aaronson S.A. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science. 251:1991;802-804.
4. Bussolino F., Di Renzo M.F., Ziche M., Bocchieto E., Olivero M., Naldini L., Gaudino G., Tamagnone L., Coffer A., Comoglio P.M. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J. Cell Biol. 119:1992;629-641.
5. Cantley L.C., Auger K.R., Carpenter C., Duckworth B., Graziani A., Kapeller R., Soltoff S. Oncogenes and signal transduction. Cell. 64:1991;281-302.
6. Darnell J.E., Jelinek W.R., Molly G.R. Biogenesis of mRNA: genetic regulation in mammalian cells. Science. 181:1973;1215-1221.
7. Feinberg A.P., Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13.
8. Gherardi E., Gray J., Stoker M., Perryman M., Furlong R. Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc. Natl. Acad. Sci. USA. 86:1989;5844-5848.
9. Gohda E., Tsubouchi H., Nakayama H., Hirono S., Sakiyama O., Takahashi K., Miyazaki H., Hashimoto S., Daikuhara Y. Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J. Clin. Invest. 81:1988;414-419.
10. Grant D.S., Kleinman H.K., Goldberg I.D., Bhargava M.M., Nickoloff B.J., Kinsella J.L., Polverni P., Rosen E.M. Scatter factor induces blood vessel formation in vivo. Proc. Natl. Acad. Sci. USA. 90:1993;1937-1941.
11. Kan M., Zhang G., Zarnegar R., Michalopoulos G., Myoken Y., McKeehan W.L., Stevens J.I. Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE. Biochem. Biophys. Res. Commun. 174:1991;331-337.
12. Komada M., Kitamura N. Regulatory role of major tyrosine phosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor). J. Biol. Chem. 269:1994;16131-16136.
13. Komada M., Kitamura N. Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol. Cell. Biol. 15:1995;6213-6221.
14. Komada M., Masaki R., Yamamoto A., Kitamura N. Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J. Biol. Chem. 272:1997;20538-20544.
15. Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:1987;8125-8148.
16. Montesano R., Matsumoto K., Nakamura T., Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell. 67:1991;901-908.
17. Mu F.T., Callaghan J.M., Steele-Mortimer O., Stenmark H., Parton R.G., Campbell P.L., McCluskey J., Yeo J.P., Tock E.P.C., Toh B.H. EEA1, an early endosome-associated protein. J. Biol. Chem. 270:1995;13503-13511.
18. Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., Tashiro K., Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature. 342:1989;440-443.
19. Naldini L., Weidner K.M., Vigna E., Gaudino G., Bardelli A., Ponzetto C., Narsimhan R.P., Hartmann G., Zarnegar R., Michalopoulos G.K., Birchmeier W., Comoglio P.M. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J. 10:1991;2867-2878.
20. Park M., Dean M., Kaul K., Braun M.J., Gonda M.A., Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc. Natl. Acad. Sci. USA. 84:1987;6379-6383.
21. Piper R.C., Cooper A.A., Yang H., Stevens T.H. VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol. 131:1995;603-617.
22. Rubin J.S., Chan A.M.-L., Bottaro D.P., Burgess W.H., Taylor W.G., Cech A.C., Hirschfield D.W., Wong J., Miki T., Finch P.W., Aaronson S.A. A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc. Natl. Acad. Sci. USA. 88:1991;415-419.
23. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
24. Stoker M. Effect of scatter factor on motility of epithelial cells and fibroblasts. J. Cell. Physiol. 139:1989;565-569.
25. Takeshita T., Arita T., Asao H., Tanaka N., Higuchi M., Kuroda H., Kaneko K., Munakata H., Endo Y., Fujita T., Sugamura K. Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM. Biochem. Biophys. Res. Commun. 225:1996;1035-1039.
26. Ullrich A., Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell. 61:1990;203-212.
27. Webb G.C., Zhang J., Garlow S.J., Wesp A., Riezman H., Jones E.W. Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosome. Mol. Biol. Cell. 8:1997;871-895.
28. Weidner K.M., Arakaki N., Hartmann G., Vandekerckhove J., Weingart S., Rieder H., Fonatsch C., Tsubouchi H., Hishida T., Daikuhara Y., Birchmeier W. Evidence for the identity of huma scatter factor and human hepatocyte growth factor. Proc. Natl. Acad. Sci. USA. 88:1991;7001-7005.
29. Weidner K.M., Behrens J., Vandekerckhove J., Birchmeier W. Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J. Cell Biol. 111:1990;2097-2108.
30. Weisman L.S., Wickner W. Molecular characterization of VAC1, a gene required for vacuole inheritance and vacuole protein sorting. J. Biol. Chem. 267:1992;618-623.
31. Yamamoto A., DeWald D.B., Boronenkov I.V., Anderson R.A., Emr S.D., Koshland D. Novel PI(4)P 5-kinase homolog, Fab1p, essential for normal vacuole function and morphology in yeast. Mol. Biol. Cell. 6:1995;525-539.