-
1
-
-
0029134614
-
Feline immunodeficiency virus reverse transcriptase: Expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits
-
Amacker M., Hottiger M., Hübscher U. Feline immunodeficiency virus reverse transcriptase expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits. J. Virol. 69:1995;6273-6279
-
(1995)
J. Virol.
, vol.69
, pp. 6273-6279
-
-
Amacker, M.1
Hottiger, M.2
Hübscher, U.3
-
2
-
-
0031041158
-
HIV-1 nucleocapsid protein and replication protein a influence the strand displacement DNA synthesis of lentiviral reverse transcriptases
-
Amacker M., Hottiger M., Mossi R., Hübscher U. HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptases. AIDS. 11:1997;534-536
-
(1997)
AIDS
, vol.11
, pp. 534-536
-
-
Amacker, M.1
Hottiger, M.2
Mossi, R.3
Hübscher, U.4
-
3
-
-
0028144874
-
Site-directed mutagenesis of HIV reverse transcriptase to probe enzyme processivity and drug binding
-
Beard W.A., Wilson S.H. Site-directed mutagenesis of HIV reverse transcriptase to probe enzyme processivity and drug binding. Curr. Opin. Biotech. 5:1994;414-421
-
(1994)
Curr. Opin. Biotech.
, vol.5
, pp. 414-421
-
-
Beard, W.A.1
Wilson, S.H.2
-
4
-
-
0026500566
-
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1
-
Boyer P.L., Ferris A.L., Hughes S.H. Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. J. Virol. 66:1992;1031-1039
-
(1992)
J. Virol.
, vol.66
, pp. 1031-1039
-
-
Boyer, P.L.1
Ferris, A.L.2
Hughes, S.H.3
-
5
-
-
0025975153
-
Crosslinking of substrates occurs exclusively to the p66 subunit of heterodimeric HIV-1 reverse transcriptase
-
Cheng N., Painter G.R., Furman P.A. Crosslinking of substrates occurs exclusively to the p66 subunit of heterodimeric HIV-1 reverse transcriptase. Biochem. Biophys. Res. Commun. 174:1991;785-789
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.174
, pp. 785-789
-
-
Cheng, N.1
Painter, G.R.2
Furman, P.A.3
-
6
-
-
0025908083
-
Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase
-
Davies F J.d., Hostomska Z., Hostomsky Z., Jordan S.R., Matthews D.A. Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase. Science. 252:1991;88-95
-
(1991)
Science
, vol.252
, pp. 88-95
-
-
D, J.D.F.1
Hostomska, Z.2
Hostomsky, Z.3
Jordan, S.R.4
Matthews, D.A.5
-
7
-
-
0028447435
-
Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer
-
Ding J., Jacobo-Molina A., Tantillo C., Lu X., Nanni R.G., Arnold E. Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer. J. Mol. Recogn. 7:1994;157-161
-
(1994)
J. Mol. Recogn.
, vol.7
, pp. 157-161
-
-
Ding, J.1
Jacobo-Molina, A.2
Tantillo, C.3
Lu, X.4
Nanni, R.G.5
Arnold, E.6
-
8
-
-
0025279437
-
Efficient production of chicken egg yolk antibodies against a conserved mammalian protein
-
Gassmann M., Thommes P., Weiser T., Hübscher U. Efficient production of chicken egg yolk antibodies against a conserved mammalian protein. FASEB J. 4:1990;2528-2532
-
(1990)
FASEB J.
, vol.4
, pp. 2528-2532
-
-
Gassmann, M.1
Thommes, P.2
Weiser, T.3
Hübscher, U.4
-
9
-
-
0029913218
-
Human immunodeficiency virus type 1 reverse transcriptase
-
Hottiger M., Hübscher U. Human immunodeficiency virus type 1 reverse transcriptase. Biol. Chem. 377:1996;97-120
-
(1996)
Biol. Chem.
, vol.377
, pp. 97-120
-
-
Hottiger, M.1
Hübscher, U.2
-
10
-
-
0028144429
-
Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits
-
Hottiger M., Podust V.N., Thimmig R.L., McHenry C., Hübscher U. Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits. J. Biol. Chem. 269:1994;986-991
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 986-991
-
-
Hottiger, M.1
Podust, V.N.2
Thimmig, R.L.3
McHenry, C.4
Hübscher, U.5
-
11
-
-
0028934998
-
The large subunit of HIV-1 reverse transcriptase interacts with beta-actin
-
Hottiger M., Gramatikoff K., Georgiev O., Chaponnier C., Schaffner W., Hübscher U. The large subunit of HIV-1 reverse transcriptase interacts with beta-actin. Nucl. Acids Res. 23:1995;736-741
-
(1995)
Nucl. Acids Res.
, vol.23
, pp. 736-741
-
-
Hottiger, M.1
Gramatikoff, K.2
Georgiev, O.3
Chaponnier, C.4
Schaffner, W.5
Hübscher, U.6
-
12
-
-
0026718788
-
Contribution of the p51 subunit of HIV-1 reverse transcriptase to enzyme processivity
-
Huang S.C., Smith J.R., Moen L.K. Contribution of the p51 subunit of HIV-1 reverse transcriptase to enzyme processivity. Biochem. Biophys. Res. Commun. 184:1992;986-992
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.184
, pp. 986-992
-
-
Huang, S.C.1
Smith, J.R.2
Moen, L.K.3
-
13
-
-
0028096227
-
Modulation of HIV-1 reverse transcriptase function in "selectively deleted" p66/p51 heterodimers
-
Jacques P.S., Wohrl B.M., Howard K.J., Le Grice F S. Modulation of HIV-1 reverse transcriptase function in "selectively deleted" p66/p51 heterodimers. J. Biol. Chem. 269:1994;1388-1393
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1388-1393
-
-
Jacques, P.S.1
Wohrl, B.M.2
Howard, K.J.3
Le Grice, F.S.4
-
14
-
-
0026693137
-
Crystal structure at 3. 5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt L.A., Wang J., Friedman J.M., Rice P.A., Steitz T.A. Crystal structure at 3. 5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science. 256:1992;1783-1790
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
15
-
-
0025191211
-
Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography
-
Le Grice S.F., Gruninger-Leitch F. Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography. Eur. J. Biochem. 187:1990;307-314
-
(1990)
Eur. J. Biochem.
, vol.187
, pp. 307-314
-
-
Le Grice, S.F.1
Gruninger-Leitch, F.2
-
16
-
-
0026070438
-
Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase
-
Le Grice F S., Naas T., Wohlgensinger B., Schatz O. Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase. EMBO J. 10:1991;3905-3911
-
(1991)
EMBO J.
, vol.10
, pp. 3905-3911
-
-
Le Grice, F.S.1
Naas, T.2
Wohlgensinger, B.3
Schatz, O.4
-
17
-
-
0023829221
-
Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli
-
Mous J., Heimer E.P., LeGrice S.F.J. Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli. J. Virol. 62:1988;1433-1436
-
(1988)
J. Virol.
, vol.62
, pp. 1433-1436
-
-
Mous, J.1
Heimer, E.P.2
Legrice, S.F.J.3
-
18
-
-
0024998733
-
Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses
-
North T.W., Cronn R.C., Remington K.M., Tandberg R.T. Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses. Antimicrob. Agents Chemother. 34:1990;1505-1507
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 1505-1507
-
-
North, T.W.1
Cronn, R.C.2
Remington, K.M.3
Tandberg, R.T.4
-
19
-
-
0026078484
-
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5′-triphosphates of carbovir, 3′-azido-3′-deoxythymidine, 2′,3′-dideoxyguanosine and 3′-deoxythymidine
-
Parker W.B., White E.L., Shaddix S.C., Ross L.J., Buckheit R.W. Jr, Germany J.M., Secrist J.A.d., Vince R., Shannon W.M. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5′-triphosphates of carbovir, 3′-azido-3′-deoxythymidine, 2′,3′-dideoxyguanosine and 3′-deoxythymidine. J. Biol. Chem. 266:1991;1754-1762
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1754-1762
-
-
Parker, W.B.1
White, E.L.2
Shaddix, S.C.3
Ross, L.J.4
Buckheit Jr., R.W.5
Germany, J.M.6
Secrist, J.A.D.7
Vince, R.8
Shannon, W.M.9
-
20
-
-
0027319733
-
Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins
-
Podust V.N., Hübscher U. Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins. Nucl. Acids Res. 21:1993;841-846
-
(1993)
Nucl. Acids Res.
, vol.21
, pp. 841-846
-
-
Podust, V.N.1
Hübscher, U.2
-
21
-
-
0025222838
-
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5′-triphosphate and 3′-azido-3′-deoxythymidine 5′-triphosphate
-
Reardon J.E., Miller W.H. Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5′-triphosphate and 3′-azido-3′-deoxythymidine 5′-triphosphate. J. Biol. Chem. 265:1990;20302-20307
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20302-20307
-
-
Reardon, J.E.1
Miller, W.H.2
-
22
-
-
0028012038
-
Rapid phenotypic reversion of zidovudine-resistant feline immunodeficiency virus without loss of drug-resistant reverse transcriptase
-
Remington K.M., Zhu Y.Q., Phillips T.R., North T.W. Rapid phenotypic reversion of zidovudine-resistant feline immunodeficiency virus without loss of drug-resistant reverse transcriptase. J. Virol. 68:1994;632-637
-
(1994)
J. Virol.
, vol.68
, pp. 632-637
-
-
Remington, K.M.1
Zhu, Y.Q.2
Phillips, T.R.3
North, T.W.4
-
23
-
-
0028947588
-
High resolution structures of HIV-1 RT from four RT-inhibitor complexes
-
Ren J.S., Esnouf R., Garman E., Somers D., Ross C., Kirby I., Keeling J., Darby G., Jones Y., Stuart D., Stammers D. High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Nature Struct. Biol. 2:1995;293-302
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 293-302
-
-
Ren, J.S.1
Esnouf, R.2
Garman, E.3
Somers, D.4
Ross, C.5
Kirby, I.6
Keeling, J.7
Darby, G.8
Jones, Y.9
Stuart, D.10
Stammers, D.11
-
24
-
-
0025297454
-
Dimerization of human immunodeficiency virus type 1 reverse transcriptase. a target for chemotherapeutic intervention
-
Restle T., Muller B., Goody R.S. Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention. J. Biol. Chem. 265:1990;8986-8988
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8986-8988
-
-
Restle, T.1
Muller, B.2
Goody, R.S.3
-
25
-
-
0023886222
-
Enzyme activity gel analysis of human immunodeficiency virus reverse transcriptase
-
Starnes M.C., Gao W.Y., Ting R.Y., Cheng Y.C. Enzyme activity gel analysis of human immunodeficiency virus reverse transcriptase. J. Biol. Chem. 263:1988;5132-5134
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5132-5134
-
-
Starnes, M.C.1
Gao, W.Y.2
Ting, R.Y.3
Cheng, Y.C.4
-
26
-
-
0028172345
-
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance
-
Tantillo C., Ding J., Jacobo-Molina A., Nanni R.G., Boyer P.L., Hughes S.H., Pauwels R., Andries K., Janssen P.A., Arnold E. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. J. Mol. Biol. 243:1994;369-387
-
(1994)
J. Mol. Biol.
, vol.243
, pp. 369-387
-
-
Tantillo, C.1
Ding, J.2
Jacobo-Molina, A.3
Nanni, R.G.4
Boyer, P.L.5
Hughes, S.H.6
Pauwels, R.7
Andries, K.8
Janssen, P.A.9
Arnold, E.10
-
27
-
-
0027202093
-
Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase
-
Thimmig R.L., McHenry C.S. Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase. J. Biol. Chem. 268:1993;16528-16536
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 16528-16536
-
-
Thimmig, R.L.1
McHenry, C.S.2
-
28
-
-
0028352172
-
Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138 → Arg and Tyr-188 → His mutations
-
Zhang H., Vrang L., Backbro K., Unge T., Noreen R., Oberg B. Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138 → Arg and Tyr-188 → His mutations. Antivir. Res. 24:1994;43-57
-
(1994)
Antivir. Res.
, vol.24
, pp. 43-57
-
-
Zhang, H.1
Vrang, L.2
Backbro, K.3
Unge, T.4
Noreen, R.5
Oberg, B.6
|