Side effects of brequinar and brequinar analogues, in combination with cyclosporine, in the rat

Toxicology

Volumn 127, Issue 1-3, 1998, Pages 207-222

  Pally, Charles ^a   Smith, Diane ^a   Jaffee, Bruce ^b   Magolda, Ron ^b   Zehender, Hartmut ^a   Dorobek, Birgit ^a   Donatsch, Peter ^a   Papageorgiou, Christos ^a   Schuurman, Henk Jan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Div of Inflammatory Dis Research   (United States)

Author keywords

Brequinar; Combination toxicity; Cyclosporine; Immunosuppressant

Indexed keywords

BREQUINAR; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; NSC 386390; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG POTENTIATION; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE VILLUS ATROPHY; LEUKOPENIA; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; THROMBOCYTOPENIA; THYMUS ATROPHY; WEIGHT GAIN; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ANIMALS; BIPHENYL COMPOUNDS; BLOOD CELL COUNT; BODY WEIGHT; BONE MARROW; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; IMMUNOSUPPRESSIVE AGENTS; JEJUNUM; LEUKOPENIA; MALE; RATS; RATS, INBRED LEW; SPLEEN; THROMBOCYTOPENIA; THYMUS GLAND; TOXICITY TESTS; WEIGHT GAIN;

EID: 0032524362     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(98)00026-2     Document Type: Article

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