Inhibition of arylesterase by aliphatic alcohols

Chemico-Biological Interactions

Volumn 113, Issue 2, 1998, Pages

  Debord, Jean ^a   Dantoine, Thierry ^b   Bollinger, Jean Claude ^c   Abraham, Michael H ^d   Verneuil, Bernard ^e   Merle, Louis ^a  

^a C H U Dupuytren   (France)

^b Service de Néphrologie Dialyse Transplantation   (France)

^c UNIVERSITY OF LIMOGES   (France)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e Institut Universitaire de Technologie   (France)

Author keywords

Alcohols; Arylesterase; Inhibition; Paraoxonase; Structure activity relationships

Indexed keywords

2 PROPANOL; ALKANOL; ARYLESTERASE; BUTANOL; HEXANOL; ISETHIONIC ACID; ISOBUTANOL; ISOPENTYL ALCOHOL; METHANOL; PENTANOL; PROPANOL;

ARTICLE; ENZYME INHIBITION; HUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

CARBOXYLIC ESTER HYDROLASES; CHEMISTRY, PHYSICAL; FATTY ALCOHOLS; GENOTYPE; HUMANS; ISOENZYMES; PHENOTYPE; REGRESSION ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032524056     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(98)00018-0     Document Type: Article

References (18)

1. Mackness M.I., Durrington P.N. HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis. 115:1995;243-253.
2. Lorentz K., Flatter B., Augustin E. Arylesterase in serum: Elaboration and clinical application of a fixed-incubation method. Clin. Chem. 25:1979;1714-1720.
3. Eckerson H.W., Wyte C.M., La Du B.N. The human serum paraoxonase/arylesterase polymorphism. Am. J. Hum. Genet. 35:1983;1126-1138.
4. J. Debord, WinReg, French version 1.2 (1996). Available on the Internet at http://ourworld.compuserve.com/homepages/JDebord/statfr.htm.
5. Abraham M.H. Scales of solute hydrogen-bonding: their construction and application to physicochemical and biochemical processes. Chem. Soc. Rev. 22:1993;73-83.
6. Abraham M.H. Application of solvation equation to chemical and biochemical processes. Pure Appl. Chem. 65:1993;2503-2512.
7. Abraham M.H., Whiting G.S., Doherty R.M., Shuely W.J. Hydrogen bonding 13. A new method for characterisation of GLC stationary phases - The Laffort dataset. J. Chem. Soc. Perkin Trans. 2:1990;1451-1460.
8. H from chromatographic data. J. Chromatogr. 587:1991;213-228.
9. Abraham M.H. Hydrogen bonding 31. Construction of a scale of solute effective or summation hydrogen-bond basicity. J. Phys. Org. Chem. 6:1993;660-684.
10. Abraham M.H., McGowan J.C. The use of characteristic volumes to measure cavity terms in reversed phase liquid chromatography. Chromatographia. 23:1987;243-246.
11. Wilson L.Y., Famini G.R. Using theoretical descriptors in quantitative structure-activity relationships: Some toxicological indices. J. Med. Chem. 34:1991;1668-1674.
12. Stewart J.J.P. MOPAC 6 for IBM/PC. QCPE Bull. 15:1995;6.
13. Fernández Pacios L. ARVOMOL: Surface areas and volumes of molecules. QCPE Bull. 15:1995;47.
14. Math Soft Inc. S-plus version 3.3 for MS Windows, Seattle, WA, 1995.
15. W.N. Venables, B.D. Ripley, Modern Applied Statistics with S-plus, Springer-Verlag, New York, 1996.
16. Gupta S.P. QSAR studies on enzyme inhibitors. Chem. Rev. 87:1987;1183-1253.
17. Smith R.R., Canady W.J. Solvation effects upon the thermodynamic substrate activity; correlation with the kinetics of enzyme catalyzed reactions I. Effects of added reagents such as methanol upon alpha-chymotrypsin. Biophys. Chem. 43:1992;173-187.
18. Tanaka-Kawai H., Yomoda S. Molecular weight and substrate characteristics of human serum arylesterase following purification by immuno-affinity chromatography. Clin. Chim. Acta. 215:1993;127-138.