High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice

Cancer Letters

Volumn 127, Issue 1-2, 1998, Pages 55-61

  Kurooka, Masayuki ^a   Hongyo, Tadashi ^a   Nakajima, Hiroo ^a   Baskar, Rajamanickam ^a   Li, Li Ya ^a   Fukuda, Kazuyasu ^a   Sutoh, Kazuo ^a   Miyata, Masahiko ^a   Matsuda, Hikaru ^a   Nomura, Taisei ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Calcium channel blocker; Esophageal achalasia; Esophageal cancer; Mouse; N amyl N methylnitrosamine; Nicardipine

Indexed keywords

N METHYL N PENTYLNITROSAMINE; NICARDIPINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CONTROLLED STUDY; ESOPHAGUS ACHALASIA; ESOPHAGUS CANCER; ESOPHAGUS CARCINOMA; MOUSE; MOUSE MUTANT; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR VOLUME;

ADMINISTRATION, ORAL; ANIMALS; CALCIUM CHANNEL BLOCKERS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL ACHALASIA; ESOPHAGEAL NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NICARDIPINE; NITROSAMINES; RISK;

ANIMALIA;

EID: 0032523884     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00006-8     Document Type: Article

References (21)

1. Aggestrup S., Holm J.C., Sorensen H.R. Does achalasia predispose cancer of the esophagus? Chest. 102:1992;1013-1016.
2. Bowman F.K., Vaughn J.T., Quich C.B., Hankes G.H., Redding R.W., Purohit R.C., Rumph P.F., Powers R.D., Harper N.K. Mega-esophagus in a colt. J. Am. Vet. Med. Assoc. 172:1978;334-337.
3. Chuong J.J.H., DuBovik S., McCallum R.W. Achalasia as a risk factor for esophageal carcinoma. Dig. Dis. Sci. 29:1984;1105-1108.
4. Clifford D.H., Pirsch J.G. Myenteric ganglia cells in dogs with and without hereditary achalasia of the esophagus. Am. J. Vet. Res. 32:1971;615-619.
5. Cross F.S. Pathologic changes in megaesophagus (esophageal dystonia). Surgery. 31:1952;647-653.
6. H. Druckrey, Organospecific carcinogenesis in the digestive tract, in: W. Nakahara, S. Takayama, T. Sugimura (Eds.), Topics in Chemical Carcinogenesis, University Park Press, Baltimore, MD, 1972, pp. 73-103.
7. Fong L.Y.Y., Hsiang J.L., Lee C.L. Methylation of DNA in target and non-target organs of the rat with methylbenzylnitrosamine and dimethylnitrosamine. Int. J. Cancer. 23:1979;679-682.
8. Ghaisas S., Saranath D., Deo M.G. ICRC mouse with congenital mega-esophagus as a model to study esophageal tumorigenesis. Carcinogenesis. 10:1989;1847-1854.
9. Goldblum J.R., Whyte R.I., Orringer M.B., Appleman H.D. Achalasia, a morphologic study of 42 resected specimens. Am. J. Surg. Pathol. 18:1994;327-337.
10. Harkness J.E., Ferguson F.G. Idiopathic mega-esophagus in a rat. Lab. Anim. Sci. 29:1979;495-498.
11. Hatanaka T. Hereditary, pathology and pharmacology of a mutant mouse 101/b developing esophageal dilatation (thesis introduced by T. Nomura) (in Japanese). Osaka Daigaku Igaku Zasshi. 37:1985;63-69.
12. Hodgson R.M., Schweinsberg F., Wiessler M., Kleihues P. Mechanism of esophageal tumor induction in rats by N-nitrosomethylbenzylamine and its ring-methylated analog N-nitrosomethyl (4-methylbenzyl) amine. Cancer Res. 42:1982;2836-2840.
13. Iizuka T., Ichimura S., Kawachi T. Esophageal carcinoma in rats induced by N-amyl-N-methylnitrosamine. Gann. 71:1980;94-99.
14. H. Inohara, S. Kida, M. Okamoto, T. Hatanaka, H. Nakajima, T. Matsunaga, T. Nomura, Genetics and pathophysiology of esophageal dilatation developing in a mutant mouse 101/b, in: T. Inouye (Ed.), Recent Advances in Bronchoesophacology, Elsevier, Amsterdam, 1990, pp. 371-372.
15. H.R. Matthews, C.W. Pattisson, Esophageal carcinoma as a complication of achalasia: the screening controversy, in: N.C. Delarue, E.W. Wilkins Jr., J. Wong (Eds.), Esophageal Cancer, International Trends in General Thoracic Surgery, Mosby, St. Louis, MO, 1988, pp. 11-15.
16. Meijssen M.A.C., Tilanus H.W., van Blankenstein M., Hop W.C.J., Ong G.L. Achalasia complicated by oesophageal squamous cell carcinoma: a prospective study in 195 patients. Gut. 33:1992;155-158.
17. Peracchia A., Segalin A., Bardini R., Ruol A., Bonavina L., Baessato M. Esophageal carcinoma and achalasia: prevalence, incidence and results of treatment. Hepato-Gastroenterol. 38:1991;514-516.
18. Soifer F.R., Freeman R.G. Stricture and dilatation of the esophagus in the cat. J. Am. Vet. Med. Assoc. 156:1970;1007-1014.
19. Sons H.U., Borchard F., Muller-Jäh K., Sandmann H. Accelerated tumor induction by distal esophageal constriction in the rat under the influence of N-ethyl-N-butyl-nitrosamine. Cancer. 56:1985;2617-2621.
20. Streitz J.M. Jr., Ellis F.H. Jr., Gibb S.P., Heatley G.M. Achalasia and squamous cell carcinoma of the esophagus: analysis of 241 patients. Ann. Thorac. Surg. 59:1995;1604-1609.
21. Wychulis A.R., Woolam G.L., Andersen H.A., Ellis F.H. Jr. Achalasia and carcinoma of the esophagus. J. Am. Med. Assoc. 215:1971;1638-1641.