In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux

Journal of Biological Chemistry

Volumn 273, Issue 20, 1998, Pages 12187-12194

  Jucker, Beat M ^a,b   Lee, Joon Y ^c   Shulman, Robert G ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; GLUTAMINE; TRICARBOXYLIC ACID; CARBON;

AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; LIVER CELL; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; LIVER; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPRAGUE DAWLEY RAT;

ANIMALS; CARBON ISOTOPES; CITRIC ACID CYCLE; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032523234     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.20.12187     Document Type: Article

References (47)

1. Rabkin, M., and Blum, J. J. (1984) Biochem J. 225, 761-786
2. Beylot, M., Soloviev, M. V., David, F., Landau, B. R., and Brunengraber, H. (1995) J. Biol. Chem. 270, 1509-1514
3. DiDonato, L., Des Rosiers, C., Montgomery, J. A., David, F., Garneau, M., and Brunengraber, H. (1993) J. Biol. Chem. 268, 4170-4180
4. Magnusson, I., Schumann, W. C., Bartsch, G. E., Chandramouli, V., Kumaran, K., Wahren, J., and Landau, B. R. (1991) J. Biol. Chem. 266, 6975-6984
5. Fitzpatrick, S. M., Hetherington, H. P., Behar, K. L., and Shulman, R. G. (1990) J. Cereb. Blood Flow Metab. 10, 170-179
6. Rothman, D. L., Novotny, E. J., Shulman, G. I., Howesemau, A. M., Petroff, O. A. C., Mason, G., Nixon, T., Hanstock, C. C., Prichard, J. W., and Shulman, R. G. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9603-9606
7. Gruetter, R., Novotny, E. J., Boulware, S. D., Mason, G. F., Rothman, D. L., Shulman, G. I., Prichard, J. W., and Shulman, R. G. (1994) J. Neurochem. 63, 1377-1385
8. Chance, E. M., Seeholzer, S. H., Kobayashi, K., and Williamson, J. R. (1983) J. Biol. Chem. 258, 13785-13794
9. Weiss, R. G., Gloth, S. T., Kalil-Filho, R., Chacko, V. P., Stern, M. D., and Gerstenblith, G. (1992) Circ. Res. 70, 392-408
10. Yu, X., White, L. T., Doumen, C., Damico, L. A., LaNoue, K. F., Alpert, N. M., and Lewandowski, E. D. (1995) Biophys. J. 69, 2090-2102
11. Chatham, J. C., Forder, J. R., Glickson, J. D., and Chance, E. M. (1995) J. Biol. Chem. 270, 7999-8008
12. Cohen, S. M., Shulman, R. G., and McLaughlin, A. C. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4808-4812
13. Mason, G. F., Rothman, D. L., Behar, K. L., and Shulman, R. G. (1992) J. Cereb. Blood Flow Metab. 12, 434-447
14. Bradbury, M. W. (1993) Exp. Physiol. 78, 453-472
15. Katz, J., Wals, P., and Lee, W-N. P. (1993) J. Biol. Chem. 268, 25509-25521
16. Frahm, J., Merboldt, K. D., and Hänicke, W. (1987) J. Magn. Res. 72, 502-508
17. Rothman, D. L., Magnusson I., Katz, L. D., Shulman, R. G., and Shulman, G. I. (1991) Science 254, 573-576
18. Silver, M. S., Joseph, R. I., Chen, C. N., Sank, V. J., and Hoult, D. I. (1984) Nature 310, 681-683
19. Jucker, B. M., Hennings, A. J. M., Cline, G. W., and Shulman, G. I. (1997) J. Biol. Chem. 272, 10464-10473
20. Malloy, C. R., Sherry, A. D., and Jeffrey, F. M. H. (1988) J. Biol. Chem. 263, 6964-6971
21. Williamson, J. R., Scholz, R., Browning, E. T., Thurman, R. G., and Fukami, M. H. (1969) J. Biol. Chem. 244, 5044-5054
22. Weiss, R. G., Stern, M. D., Albuquerque, C. P., Vandegaer, K., Chacko, V. P., and Gersenblith, G. (1995) Biochim. Biophys. Acta 1243, 543-548
23. Drake, R. L., Parks, W. C., and Thompson, E. W. (1983) J. Biol. Chem. 258, 6008-6010
24. Thurman, R. G., and Scholz, R. (1977) Eur. J. Biochem. 75, 13-21
25. Taylor, W. M., Van De Pol, E., and Bygrave, F. L. (1986) Biochem. J. 233, 321-324
26. Eriksson, C. J. P., Lindros, K. O., and Forsander, O. A. (1974) Biochem. Pharmacol. 23, 2193-2195
27. Forsander, O. A. (1967) Biochem. J. 105, 93-97
28. Vogt, J. A., Yarmush, D. M., Yu, Y. M., Zupke, C., Fischman, A. J., Tompkins, R. G., and Burke, J. F. (1997) Am. J. Physiol. 272, C2049-C2062
29. Shelmet, J. J., Reichard, G. A., Skutches, C. L., Hoeldtke, R. D., Owen, O. E., and Boden, G. (1988) Am. Soc. Clin. Invest. 81, 1137-1145
30. Lieber, C. S., Lefevre, A., Spritz, N., Feinman, L., DeCarli, L. M. (1967) J. Clin. Invest. 46, 1451-1460
31. Veech, R. L., Guynn, R., and Veloso, D. (1972) Biochem. J. 127, 387-397
32. Jungermann, K., and Thurman, R. G. (1992) Enzyme 46, 33-58
33. Cline, G. W., and Shulman, G. I. (1995) J. Biol. Chem. 270, 28062-28067
34. Fafournoux, P., Demigné, C., Rémésy, C., and LeCam, A. (1983) Biochem. J. 216, 401-408
35. Kilberg, M. S., Handlogton, M. E., and Christensen, H. N. (1980) J. Biol. Chem. 255, 4011-4019
36. Jacob, R., Rosenthal, N., and Barrett, E. (1983) Am. J. Physiol. 251, E509-E514
37. Buttrose, M., McKellar, D., and Welbourne, T. C. (1987) Am. J. Physiol. 252, E746-E750
38. Welbourne, T. C., Phromphetcharat, V., Givens, G., and Joshi, S. (1986) Am. J. Physiol. 250, E457-E463
39. Partridge, W. M. (1997) Am. J. Physiol. 232, E492-E496
40. Häussinger, D., and Gerok, W. (1983) Eur. J. Biochem. 136, 421-425
41. Low, S. Y., Taylor, P. M., Hundal, H. S., and Pogson, L. I. (1992) Biochem. J. 284, 333-340
42. Schumann, W. C., Magnusson, I., Chandramouli, V., Kumaran, K., Wahren, J., and Landau, B. R. (1991) J. Biol. Chem. 266, 6985-6990
43. Jorfeldt, L., and Juhlin-Dannfelt, A. (1978) Metab. Clin. Exp. 27, 97-106
44. Lindeneg, O., Mellemgaard, K., Fabricius, J., and Lundquist, F. (1964) Clin. Sci. 27, 427-435
45. Lundquist, F., Tygstrup, N., Winkler, K., Mellemgaard, K., and Munck-Petersen, S. (1962) J. Clin. Invest. 41, 955-961
46. Des Rosiers, C., DiDonato, L, Comte, B., Laplante, A., Marcoux, C., David, F., Fernandez, C. A., and Brunengraber, H. (1995) J. Biol. Chem. 270, 10027-10036
47. Rife, J. E., and Cleland, W. W. (1980) Biochemistry 19, 2321-2328