The relationship between modulation of MDR and glutathione in MRP- overexpressing human leukemia cells

Biochemical Pharmacology

Volumn 55, Issue 8, 1998, Pages 1283-1289

  Grech, Karen V ^a   Davey, Ross A ^b   Davey, Mary W ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b Bill Walsh Cancer Res Laboratories Dept Clin Oncol Roy N Shore H ^*  (Australia)

Author keywords

Glutathione; Multidrug resistance; Multidrug resistance associated protein; P glycoprotein; SDZ PSC 833; Verapamil

Indexed keywords

ANTHRACYCLINE; ANTHRACYCLINE DERIVATIVE; BUTHIONINE SULFOXIMINE; DAUNORUBICIN; EPIPODOPHYLLOTOXIN DERIVATIVE; ETOPOSIDE; GLUTATHIONE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; VALSPODAR; VERAPAMIL;

ARTICLE; CANCER RESISTANCE; CELL VIABILITY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG MECHANISM; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

EID: 0032523026     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00562-5     Document Type: Article

References (18)

1. Kane SE. Multidrug resistance of cancer cells. Adv Drug Res. 28:1996;181-252.
2. Davey RA, Su GM, Hargrave RM, Harvie RM, Baguley BC, Davey MW. Potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA), idarubicin and paclitaxel to circumvent three multidrug resistance phenotypes in vitro. Cancer Chemother Pharmacol. 39:1997;424-430.
3. Kavallaris M. The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance. Anticancer Drugs. 8:1997;17-25.
4. Davey RA, Longhurst T, Davey MW, Belov L, Harvie RM, Hancox D, Wheeler H. Drug resistance mechanisms and MRP expression in response to epirubicin treatment in a human leukaemia cell line. Leuk Res. 19:1995;275-282.
5. Ishikawa T, Bao J-J, Yamane Y, Akimaru K, Frindrich K, Wright CD, Kuo MT. Coordinated induction of mrp/gs-x pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells. J Biol Chem. 271:1996;14981-14988.
6. Jedlitschky G, Leier I, Buchholz U, Center M, Keppler D. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res. 54:1994;4833-4836.
7. Jedlitschky G, Leier I, Buchholz U, Barnouin K, Kurz G, Keppler D. Transport of glutathione, glucuronate, and sulphate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 56:1996;988-994.
8. 4 and chemotherapeutic agents in membrane vesicles - demonstration of glutathione-dependent vincristine transport. J Biol Chem. 271:1996;9675-9682.
9. Beck WT, Mueller TJ, Tanzer LR. Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts. Cancer Res. 39:1979;2070-2076.
10. Foley GE, Lazarus H, Faber S, Geren-Uzman B, Boone AB, McCarthy RE. Continuous culture of human lymphoblast from peripheral blood of a child with acute leukaemia. Cancer. 18:1965;156-192.
11. Marks DC, Davey MW, Davey RA, Kidman AD. The MTT cell viability assay for cytotoxicity testing in multidrug resistant human leukaemic cells. Leuk Res. 16:1992;1165-1173.
12. Suzukake K, Petro BJ, Vistica DT. Reduction in GSH content of L-Pam resistant L1210 cells confers drug sensitivity. Biochem Pharmacol. 31:1982;121-124.
13. Woodcock DM, Linsenmeyer ME, Chojnowski G, Kriegler AB, Nink V, Webster LK, Sawyer WH. Reversal of multidrug resistance by surfactants. Br J Cancer. 66:1992;62-68.
14. Curtin N, Turner D. Reversal of drug-resistance by dipyridamole in multidrug resistance-associated protein (MRP)-overexpressing cells. Proc Am Assoc Cancer Res. 38:1997;591.
15. Sehested M, Friche E, Jensen PB, Demant JF. Relationship of VP-16 to the classical multidrug resistant phenotype. Cancer Res. 52:1992;2874-2879.
16. Politi PM, Arnold ST, Felsted RL, Sinha BK. P-Glycoprotein-independent mechanism of resistance to etoposide in multidrug-resistant tumour cell lines Pharmacokinetic and photoaffinity labelling studies . Mol Pharmacol. 37:1990;790-796.
17. Marquardt D, Center MS. Drug transport mechanisms in HL60 cells isolated for resistance to adriamycin Evidence for nuclear drug accumulation and redistribution in resistant cells . Cancer Res. 52:1992;3157-3163.
18. Davey MW, Hargrave RM, Davey RA. Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. Leuk Res. 20:1996;657-664.