Evidence for cytochrome P-450 catalysis and free radical involvement in the production of DNA strand breaks by benzo[a]pyrene and nitroaromatics in mussel (Mytilus edulis L.) digestive gland cells

Aquatic Toxicology

Volumn 41, Issue 3, 1998, Pages 193-212

  Mitchelmore, Carys L ^a   Birmelin, Claudia ^b,c   Chipman, J Kevin ^a   Livingstone, David R ^c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c PLYMOUTH MARINE LABORATORY   (United Kingdom)

Author keywords

1 nitropyrene; Benzo a pyrene; Comet assay; Genotoxicity; Mussel digestive gland cells; Mytilus edulis; Nitrofurantoin; Reactive oxygen species; Single cell gel electrophoresis

Indexed keywords

1 NITROPYRENE; ALPHA NAPHTHOFLAVONE; ANTIOXIDANT; AROMATIC NITRO COMPOUND; BENZO[A]PYRENE; CLOTRIMAZOLE; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; DICOUMAROL; DNA; ENZYME INHIBITOR; FREE RADICAL; NITROFURANTOIN; POLYCYCLIC AROMATIC COMPOUND; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; EXOCRINE GLAND; GENOTOXICITY; MUSSEL; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; INVERTEBRATA; MYTILUS EDULIS;

EID: 0032522756     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(97)00083-0     Document Type: Article

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