The expression of cytokine mRNA in the cauda equina of Lewis rats with experimental allergic neuritis

Journal of Neuroimmunology

Volumn 84, Issue 2, 1998, Pages 223-229

  Fujioka, Toshiki ^a   Jimi, Takahiro ^a   Hilliard, Brendan A ^a   Ventura, Elvira S ^a   Rostami, Abdolmohamad ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cytokine; Experimental allergic neuritis (EAN); Interferon gamma; Interleukin 10; Interleukin 4; Lewis rat; Messenger RNA; Polymerase chain reaction (PCR)

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; MESSENGER RNA;

ALLERGIC NEUROPATHY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUDA EQUINA; FEMALE; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032522188     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(97)00252-X     Document Type: Article

References (44)

1. Åström K.E., Webster H.deF., Arnason B.G. The initial lesion in experimental allergic neuritis: a phase and electron microscopic study. J. Exp. Med. 128:1968;469-495.
2. Bai X.F., Zhu J., Zhang G.X., Kaponides G., Höjeberg B., van der Meide P.H., Link H. IL-10 suppresses experimental autoimmune neuritis and down-regulates Th1-type immune responses. Clin. Immunol. Immunopathol. 83:1997;117-126.
3. Bancroft G.J., Kelly J.P., Kaye P.M., McDonald V., Cross C.E. Pathways of macrophage activation and innate immunity. Immunol. Lett. 43:1994;67-70.
4. Bolin L.M., Verity A.N., Silver J.E., Shooter E.M., Abrams J.S. Interleukin-6 production by Schwann cells and induction in sciatic nerve injury. J. Neurochem. 64:1995;850-858.
5. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1986;156-159.
6. Clerici M., Shearer G.M. A Th1→Th2 switch is a critical step in the etiology of HIV infection. Immunol. Today. 14:1993;107-111.
7. Collart M.A., Belin D., Vassalli J.D., de Kossodo S., Vassalli P. Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by shortlived repressors. J. Exp. Med. 164:1986;2113-2118.
8. Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147:1991;3815-3822.
9. Gilliland G., Perrin S., Blanchard K., Bunn H.F. Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. Proc. Natl. Acad. Sci. U.S.A. 87:1990;2725-2729.
10. Gregorian S.K., Lee W.P., Beck L.S., Rostami A., Amento E.P. Regulation of experimental autoimmune neuritis by transforming growth factor-beta 1. Cell. Immunol. 156:1994;102-112.
11. Hamilton T.A., Rigsbee J.E., Scott W.A., Adams D.O. Gamma-interferon enhances the secretion of arachidonic acid metabolites from murine peritoneal macrophages stimulated with phorbol diesters. J. Immunol. 134:1985;2631-2636.
12. Hartung H.P., Schaefer B., van der Meide P.H., Fierz W., Heininger K., Toyka K.V. The role of interferon-gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system. Ann. Neurol. 27:1990;247-257.
13. Howard M., O'Garra A. Biological properties of interleukin 10. Immunol. Today. 13:1992;198-200.
14. Issazadeh S., Ljungdahl Å., Höjeberg B., Mustafa M., Olsson T. Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor-α and tumor necrosis factor-β J. Neuroimmunol. 61:1995;205-212.
15. Issazadeh S., Mustafa M.I., Ljungdahl Å., Höjeberg B., Dagerlind Å., Elde R., Olsson T. Interferon-γ, interleukin 4, and transforming growth factor-β in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells. J. Neurosci. Res. 40:1995;579-590.
16. Jung S., Schlueuesener H.J., Schmidt B., Fontana A., Toyka K.V., Hartung H.-P. Therapeutic effect of transforming growth factor-β2 on actively induced EAN but not adoptive transfer EAN. Immunology. 83:1994;545-551.
17. Kennedy M.K., Torrance D.S., Picha K.S., Mohler K.M. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149:1992;2496-2505.
18. Kiefer R., Gold R., Gehrmann J., Lindholm D., Wekerle H., Kreutzberg G.W. Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. J. Neurosci. Res. 36:1993;391-398.
19. Kiefer R., Funa K., Schweitzer T., Jung S., Bourde O., Toyka K.V., Hartung H.-P. Transforming growth factor-β1 in experimental autoimmune neuritis. Cellular localization and time course. Am. J. Pathol. 148:1996;211-223.
20. La Fleur M., Underwood J.L., Rappolee D.A., Werb Z. Basement membrane and repair of injury to peripheral nerve: defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1. J. Exp. Med. 184:1996;2311-2326.
21. McKight A.J., Barclay A.N., Mason D.W. Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells. Eur. J. Immunol. 21:1991;1187-1194.
22. Moore K.W., O'Garra A., de Waal Malefyt R., Vieira P., Mosmann T.R. Interleukin-10. Annu. Rev. Immunol. 11:1993;165-190.
23. Mosmann T.R., Coffman R.L. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173.
24. Murray H.W., Spitalny G.L., Nathan C.F. Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. J. Immunol. 134:1985;1619-1622.
25. Mustafa M., Diener P., Hoejeberg B., Van der Meide P., Olsson T. T cell immunity and interferon-γ secretion during experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 31:1991;165-177.
26. Platzer C., Meisel Ch., Vogt K., Platzer M., Volk H.-D. Up-regulation of monocytic IL-10 by tumor necrosis factor-α and cAMP elevating drugs. Int. Immunol. 7:1995;517-523.
27. Rosen J.L., Brown M.J., Hickey W.F., Rostami A. Early myelin lesions in experimental allergic neuritis. Muscle and Nerve. 13:1990;629-636.
28. Rosen J.L., Brown M.J., Rostami A. Evolution of the cellular response in P2-induced experimental allergic neuritis. Pathobiology. 60:1992;108-112.
29. Rostami A., Brown M.J., Lisak R.P., Sumner A.J., Zweiman B., Pleasure D.E. The role of myelin P2 protein in the production of experimental allergic neuritis. Ann. Neurol. 16:1984;680-685.
30. Rostami A., Burns J.B., Brown M.J., Rosen J., Zweiman B., Lisak R.P., Pleasure D.E. Transfer of experimental allergic neuritis with P2-reactive T-cell lines. Cell. Immunol. 91:1985;354-361.
31. Rostami A., Gregorian S.K., Brown M.J., Pleasure D.E. Induction of severe experimental autoimmune neuritis with a synthetic peptide corresponding to the 53-78 amino acid sequence of the myelin P2 protein. J. Neuroimmunol. 30:1990;145-151.
32. Saida T., Saida K., Dorfman S.H., Silberberg D.H., Sumner A.J., Manning M.C., Lisak R.P., Brown M.J. Experimental allergic neuritis induced by sensitization with galactocerebroside. Science. 204:1979;1103-1106.
33. Schmidt B., Stoll G., van der Meide P., Jung S., Hartung H.-P. Transient cellular expression of gamma-interferon in myelin-induced and T-cell line-mediated experimental autoimmune neuritis. Brain. 115:1992;1633-1646.
34. Sher A., Fiorentino D., Caspar P., Pearce E., Mosmann T. Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J. Immunol. 147:1991;2713-2716.
35. Siegling A., Lehmann M., Platzer C., Emmrich F., Volk H.-D. A novel multispecific competitor fragment for quantitative PCR analysis of cytokine gene expression in rats. J. Immunol. Methods. 177:1994;23-28.
36. Smith M.E., Forno L.S., Hofmann W.W. Experimental allergic neuritis in the Lewis rat. J. Neuropathol. Exp. Neurol. 38:1979;377-391.
37. Stevens A., Schabet M., Schott K., Wiethölter H. Role of endoneural cells in experimental allergic neuritis and characterisation of a resident phagocytic cell. Acta Neuropathol. 77:1989;412-419.
38. Waksmann B.H., Adams R.D. Allergic neuritis; an experimental disease of rabbits induced by the injection of peripheral nervous tissue and adjuvants. J. Exp. Med. 102:1955;213-236.
39. Wang A.M., Doyle M.V., Mark D.F. Quantitation of mRNA by the polymerase chain reaction. Proc. Natl. Acad. Sci. U.S.A. 86:1989;9717-9721.
40. Wong H.L., Lotze M.T., Wahl L.M., Wahl S.M. Administration of recombinant IL-4 to humans regulates gene expression, phenotype, and function in circulating monocytes. J. Immunol. 148:1994;2118-2125.
41. Young H.A., Hardy K.J. Role of interferon-gamma in immune cell regulation. J. Leukocyte Biol. 58:1995;373-381.
42. Zettl U.K., Gold R., Toyka K.V., Hartung H.P. In situ demonstration of T cell activation and elimination in peripheral nervous system during experimental autoimmune neuritis in the Lewis rat. Acta Neuropathol. 91:1996;360-367.
43. Zhu J., Link H., Mix E., Olsson T., Huang W.-X. Th1-like cell response to peripheral nerve myelin components over the course of experimental allergic neuritis in Lewis rats. Acta Neurol. Scand. 90:1994;19-25.
44. Zhu J., Mix E., Olsson T., Link H. Cellular mRNA expression of interferon-gamma, IL-4, and transforming growth factor-beta (TGF-β) by rat mononuclear cells stimulated with peripheral nerve myelin antigens in experimental allergic neuritis. Clin. Exp. Immunol. 98:1994;306-312.