A substrate-induced change in the stereospecificity of the serine-hydroxymethyltransferase-catalysed exchange of the α-protons of amino acids. Evidence for a second catalytic site

European Journal of Biochemistry

Volumn 252, Issue 1, 1998, Pages 113-117

  Fitzpatrick, Teresa B ^a   Malthouse, J Paul G ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

proton exchange; Amino acids; Pyridoxal 5' phosphate; Serine hydroxymethyltransferase; Stereospecificity

Indexed keywords

AMINO ACID; BACTERIAL ENZYME; BUTYRIC ACID; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; HEXANOIC ACID DERIVATIVE; NORLEUCINE; PYRIDOXAL 5 PHOSPHATE; SCHIFF BASE; VALERIC ACID DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME KINETICS; ESCHERICHIA COLI; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL; PROTEIN TRANSPORT; STEREOSPECIFICITY;

AMINO ACIDS; BACTERIAL PROTEINS; BINDING SITES; BOROHYDRIDES; BUTYRIC ACIDS; CAPROATES; CARBON ISOTOPES; CATALYSIS; DEUTERIUM; ESCHERICHIA COLI; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; KINETICS; MOLECULAR CONFORMATION; PENTANOIC ACIDS; PROTONS; PYRIDOXAL PHOSPHATE; SCHIFF BASES; SUBSTRATE SPECIFICITY; TETRAHYDROFOLATES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032519626     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2520113.x     Document Type: Article

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