Pancreatic blood flow and its role in the pathophysiology of pancreatitis

Journal of Surgical Research

Volumn 75, Issue 1, 1998, Pages 81-89

  Lewis, M P N ^a   Reber, H A ^a   Ashley, S W ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CHOLECYSTOKININ; ENDOTHELIN; NITRIC OXIDE; SECRETIN;

ACUTE PANCREATITIS; CHRONIC PANCREATITIS; FUNCTIONAL ANATOMY; HUMAN; INNERVATION; NONHUMAN; PANCREAS BLOOD FLOW; PRIORITY JOURNAL; REVIEW;

EID: 0032519321     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1998.5268     Document Type: Review

References (90)

1. Meyer, J. Pancreatic physiology, Gastrointestinal Disease: Pathophysiology, Diagnosis, Management, Philadelphia, PA, Saunders, 1983, 1426, 1435.
2. Case R., Scratcherd T., Wynne R. The origin and secretion of pancreatic juice bicarbonate. J. Physiol. 210:1970;1-15.
3. Klar E., Messmer K., Warshaw A. L., Herfarth C. Pancreatic ischaemia in experimental acute pancreatitis: Mechanism, significance and therapy. Br. J. Surg. 77:1990;1205-1210.
4. Papp, M. Role of the circulation in acute pancreatitis, P. KveitysJ. BarrowmanD. Granger, Pathophysiology of the Splanchnic Circulation, Boca Raton, FL, CRC Press, 1987, 119, 135.
5. Harvey M. H., Wedgwood K. R., Reber H. A. Vasoactive drugs, microvascular permeability, and hemorrhagic pancreatitis in cats. Gastroenterology. 93:1987;1296-1300.
6. Ebbehoj N., Svensen L., Madsen P. Pancreatic tissue pressure: Techniques and pathophysiological aspects. Scand. J. Gastroenterol. 19:1984;1066-1068.
7. Singh S. M., Reber H. A. The pathology of chronic pancreatitis. World J. Surg. 14:1990;2-10.
8. Mandelbaum I., Morgan C. Pancreatic blood flow and its relationship to insulin secretion during extracorporeal circulation. Ann. Surg. 170:1969;753-758.
9. Kuznetsova E. Characteristics of blood supply in the pancreas during different phases of its activity. Fed. Proc. (Trans. Suppl.). 22:1963;99-104.
10. Frogge J., Hermreck A., Thal A. Metabolic and hemodynamic effects of secretin and pancreozymin on the pancreas. Surgery. 68:1970;498-502.
11. Goodhead B., Himal H., Zanbilowicz J. Relationship between pancreatic secretion and pancreatic blood flow. Gut. 11:1970;62-68.
12. Delaney J., Grim E. Influence of hormones and drugs on canine pancreatic blood flow. Am. J. Physiol. 211:1966;1398-1403.
13. Price B., Jaffe B., Zinner M. Effect of exogenous somatostatin infusion on gastrointestinal blood flow and hormones in the conscious dog. Gastroenterology. 88:1984;80-85.
14. Becker H., Manganaro A., Lazar H., Mulder D., Buckberg G. Limitations of studying splanchnic blood flow during anaesthesia. Surg. Forum. 30:1979;347-349.
15. Eicheiter P., Schenk W. Hemodynamics of pancreatic secretion. Arch. Surg. 93:1966;200-207.
16. Knol J., Edgcomb L., Inman M., Eckhauser F. Low molecular weight dextran in experimental pancreatitis: Effects on pancreatic microcirculation. J. Surg. Res. 35:1983;73-82.
17. Ercan M., Bor M., Bekdik C., Oner G. Measurement of pancreatic blood flow in the dog by Xe clearance technique. Pfluger's Arch. 348:1974;51-57.
18. Aune S., Semb L. The effect of secretin and pancreozymin on pancreatic blood flow in the conscious and anesthetized dog. Acta Physiol. Scand. 76:1969;406-414.
19. Studley J. G., Mathie R. T., Blumgart L. H. Blood flow measurement in the canine pancreas. J. Surg. Res. 42:1987;101-115.
20. Machens H., Senninger N., Runkel N., Frank G., von Kummer R., Herfarth C. Advantages and disadvantages of using the hydrogen clearance technique to measure pancreatic blood flow. Eur. J. Surg. 158:1992;113-116.
21. Prinz R. A. Mechanisms of acute pancreatitis. Vascular etiology. Int. J. Pancreatol. 9:1991;31-38.
22. Lewis G. The role of plasma kinins as mediators of functional vasodilation. Gastroenterology. 52:1967;406-413.
23. Lanciault G., Jacobson E. The gastrointestinal circulation. Gastroenterology. 71:1976;851-859.
24. Tynkel H., Hollander F. The relation between pancreatic secretion and local blood flow. Gastroenterology. 32:1957;633-641.
25. Holton P., Jones M. Some observations on change in the blood content of the cat's pancreas during activity. J. Physiol. 150:1960;479-486.
26. Beijer H., Brouwer F., Charbon G. Time course and sensitivity of secretin stimulated pancreatic secretion and blood flow in the anesthetized dog. Scand. J. Gastroenterol. 14:1979;295-300.
27. Conter R., Washington J., Kauffman G. J. Stimulated pancreatic exocrine secretion does not require pancreatic hyperemia in rats. Potential cholinergic role. Dig. Dis. Sci. 38:1993;1270-1277.
28. Lenninger S. Effects of acetylcholine and papaverine on the secretion and blood flow from the pancreas of the cat. Acta Physiol. Scand. 89:1973;260-268.
29. Sarles H., Sahel J., Staub J., Bourry J., Laugier R. Chronic pancreatitis. Sarles H. A. The Exocrine Pancreas. 1979;349-371 Saunders, London.
30. Harper S. L., Pitts V. H., Granger D. N., Kvietys P. R. Pancreatic tissue oxygenation during secretory stimulation. Am. J. Physiol. 250:1986;316-322.
31. Ashley S. W., Schwarz M., Alvarez C., Nguyen T. N., Vdovenko A., Reber H. A. Pancreatic interstitial pH regulation: Effects of secretory stimulation. Surgery. 115:1994;503-509.
32. Pascal J., Roux P., Vaysee N., Lacroix A., Martinel C., Ribet A. Respiratory exchanges and acid-base balance during perfusion of ex-vivo isolated pancreas. Dig. Dis. Sci. 21:1976;381-388.
33. DeMar A. R., Lake R., Fink A. S. The effect of pancreatic polypeptide and peptide YY on pancreatic blood flow and pancreatic exocrine secretion in the anesthetized dog. Pancreas. 6:1991;9-14.
34. Pawlik W. W., Gustaw P., Sendur R., Czarnobilski K., Hottenstein O. D., Konturek S. J. Effects of peptide YY on pancreatic blood flow and oxygen consumption. Pol. J. Pharmacol. Pharm. 44:1992;289-298.
35. Furness J., Costa M. The Enteric Nervous System. 1987;Churchill Livingstone, London.
36. Folkow B., Lewis D., Lundgren O., Mellander S., Wallentin I. The effect of graded vasoconstrictor fibre stimulation on the intestinal resistance and capacitance vessels. Acta Physiol. Scand. 61:1964;445-457.
37. Inoue K., Kawano T., Kogire M., Takaori K., Suzuki T., Tobe T. Microcirculatory response of the pancreas to feeding, sham feeding, and truncal vagotomy in conscious dogs. Pancreas. 8:1993;28-33.
38. Kvietys P., McLendon J., Bulkley G., Perry M., Granger D. Pancreatic circulation: Intrinsic regulation. Am. J. Physiol. 242:1982;596-602.
39. Konturek S. J., Bilski J., Konturek P. K., Cieszkowski M., Pawlik W. Role of endogenous nitric oxide in the control of canine pancreatic secretion and blood flow. Gastroenterology. 104:1993;896-902.
40. Patel A., Toyama M., Nguyen T., Cohen G., Ignarro L., Reber H., Ashley S. Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats. Gastroenterology. 108:1995;1215-1220.
41. MacLean M. R., Randall M. D., Hiley C. R. Effects of moderate hypoxia, hypercapnia and acidosis on haemodynamic changes induced by endothelin-1 in the pithed rat. Br. J. Pharmacol. 98:1989;1055-1065.
42. Hof R., Hof A., Takiguchi Y. Massive regional differences in the vascular effects of endothelin. J. Hypertens. 7:1989;274-275.
43. Takaori K., Inoue K., Kogire M., Higashide S., Tun T., Aung T., Doi R., Fujii N., Tobe T. Effects of endothelin on the microcirculation of the pancreas. Life Sci. 51:1992;615-622.
44. Lehoux S., Plante G. E., Sirois M. G., Sirois P., D'Orleans-Juste P. Phosphoramidon blocks big-endothelin-1 but not endothelin-1 enhancement of vascular permeability in the rat. Br. J. Pharmacol. 107:1992;996-1000.
45. Kivisaari L. Microvasculature of the human pancreas. A microangiographic study. Scand. J. Gastroenterol. 14:1979;683-687.
46. Nordback I., Lauslahti K. Clinical pathology of acute necrotising pancreatitis. J. Clin. Pathol. 39:1986;68-74.
47. Pitkaranta P., Kivisaari L., Nordling S., Nuutinen P., Schroder T. Vascular changes of pancreatic ducts and vessels in acute necrotizing and in chronic pancreatitis in humans. Int. J. Pancreatol. 8:1991;13-22.
48. Knape W. Untersuchungen (iber Pankreashamorrhagie, Pankreas- und Fettgewebsnekrose. Virchow Arch. Pathol. Anat. 207:1912;277-320.
49. Popper H., Nechels H., Russel K. Transition of pancreatic edema into pancreatic necrosis. Surg. Gynecol. Obstet. 99:1948;83-90.
50. Papp M., Makara G., Hajtman B., Csaki L. A quantitative study of pancreatic blood flow in experimental pancreatitis. Gastroenterology. 51:1966;524-528.
51. Opie E. The etiology of acute hemorrhagic pancreatitis. John Hopkins Hosp. Bull. 12:1901;182-191.
52. Donaldson L., Williams R., Schenk W. Experimental pancreatitis: Effect of plasma and dextran on pancreatic blood flow. Surgery. 84:1978;313-320.
53. Thal A. Studies on pancreatitis. IV. The pathogenesis of bile pancreatitis. Surg. Forum. 5:1954;391-394.
54. Goodhead B. Vascular factors in the pathogenesis of acute haemorrhagic pancreatitis. Ann. R. Coll. Surg. Engl. 45:1969;80-86.
55. Studley J., Mathie R., Gibbons M., Blumgart L. Blood flow and perfusion in acute haemorrhagic pancreatitis in the dog. Gut. 27:1986;958-963.
56. Heinkel K. Die Ratte als Versuchstier in der experimentellen Pankreasdiagnostik. II. Mittelung. Die Erzeugung einer akuten hamorrhagischen Pankreatitis durch Injection von Gallensaure in den Ductus pancreaticus. Klin. Wochenschr. 31:1953;815-821.
57. Aho H., Koskensalo S.-L., Nevalainen T. Experimental pancreatitis in the rat. Scand. J. Gastroenterol. 15:1980;411-416.
58. Donahue P., Akimoto H., Ferguson J., Nyhus L. Vasoactive drugs in acute pancreatitis. Arch. Surg. 119:1984;477-480.
59. Kusterer K., Enghofer M., Zendier S., Bloche C., Usadel K. Microcirculatory changes in sodium taurocholate induced pancreatitis in rats. Am. J. Physiol. 260:1991;346-351.
60. Knoefel W. T., Kollias N., Warshaw A. L., Waldner H., Nishioka N. S., Rattner D. W. Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat. Surgery. 116:1994;904-913.
61. Lewis M., Kusske A., Todd K., Toyama M., Rongione A., Reber H., Ashley S. Improvement of experimental acute pancreatitis by an endothelin ETa/ETb receptor antagonist. Gastroenterology. 110:1996;A411.
62. McEntee G., Leahy A., Cottell D., Dervan P., Fitzpatrick J. Three dimensional morphological study of the pancreatic microvasculature in caerulein-induced experimental pancreatitis. Br. J. Surg. 76:1989;853-855.
63. Berry A., Millar A., Taylor T. Pancreatic blood flow in experimental acute pancreatitis. Dig. Dis. Sci. 27:1982;444-448.
64. Lehtola A., Kivilaakso E., Puolakkainen P., Karonen S.-L., Lempinen M., Schroder T. Effects of Dextran 70 versus crystalloids in the microcirculation of porcine hemorrhagic pancreatitis. Surg. Gynecol. Obstet. 162:1986;556-561.
65. Lampel M., Kern H. Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. Virchow's Arch. A Pathol. Anat. Histol. 373:1977;97-117.
66. Lewis M., Kusske A., Todd K., Toyama M., Ashley S., Reber H. An endothelin ETa/ETb receptor antagonist improves the severity of experimental pancreatitis in rats. Surg. Forum. 47:1996;135-137.
67. Konturek S., Dembinski A., Konturek P., Warzecha Z., Jaworek J., Gustaw P., Tomaszewska R., Stachura J. Role of platelet activating factor in pathogenesis of acute pancreatitis in rats. Gut. 33:1992;1268-1274.
68. Becker H., Vinten J. J., Buckberg G. D., Bugyi H. I. Correlation of pancreatic blood flow and high-energy phosphates during experimental pancreatitis. Eur. Surg. Res. 14:1982;203-210.
69. Studley J., Wu S. Evaluation of the effects and mode of action of steroids in experimental pancreatitis in dogs. Am. J. Surg. 143:1982;761-764.
70. Donaldson L., Shenk W. Experimental acute pancreatitis: The changes in pancreatic oxygen consumption and the effect of dextran 40. Ann. Surg. 190:1979;728-735.
71. Papp M., Ungvari G., Nometh P., Munkicsi L., Zubek L. The effect of bile-induced pancreatitis on the intrapancreatic vascular pattern in dogs. Scand. J. Gastroenterol. 4:1969;681-689.
72. Wulff K., Sjostrom B. Influence of acute pancreatitis on central hemodynamic, regional blood flow distribution and arteriovenous shunting in the dog. Eur. Surg. Res. 6:1974;354-363.
73. Gabrys-Pomykala B., Holiau O., Mackenzie M., Nyhus L., Bombeck C. Adenyl cyclase and cyclic AMP in acute experimental pancreatitis. Am. J. Surg. 133:1977;156-161.
74. Nordback L. H., Clemens J. A., Chacko V. P., Olson J. L., Cameron J. L. Changes in high-energy phosphate metabolism and cell morphology in four models of acute experimental pancreatitis. Ann. Surg. 213:1991;341-349.
75. Schiller W., Anderson M. Microcirculation of the normal and inflammed canine pancreas. Ann. Surg. 181:1975;466-470.
76. Schroder T., Kivisaari L., Standertskjold-Nordenstam C.-G., Somer K., Lehtola A., Puolakkainen P., Karonen S.-L., Kivilaakso E., Lempinen M. Pancreatic blood flow and contrast enhancement in computed tomography during experimental pancreatitis. Eur. Surg. Res. 17:1985;286-291.
77. Machens H., Senninger N., Runkel N., Frank G., von Kummer R., Herfarth C. Use of the hydrogen clearance technique for measurements of pancreatic blood flow. J. Surg. Res. 55:1993;122-130.
78. Boijsen E., Tylen U. Vascular changes in chronic pancreatitis. Acta Radiol. Diagn. 12:1972;34-48.
79. Karanjia N. D., Singh S. M., Widdison A. L., Lutrin F. J., Reber H. A. Pancreatic ductal and interstitial pressures in cats with chronic pancreatitis. Dig. Dis. Sci. 37:1992;268-273.
80. Reber H. A., Karanjia N. D., Alvarez C., Widdison A. L., Leung F. W., Ashley S. W., Lutrin F. J. Pancreatic blood flow in cats with chronic pancreatitis. Gastroenterology. 103:1992;652-659.
81. Lewis M., Lo S., Reber P., Patel A., Toyama M., Kusske A., Reber H., Ashley S. Endoscopic measurement of pancreatic blood flow: Alterations in patients with chronic pancreatitis. Gastroenterology. 110:1996;A411.
82. Ishida H., Makino T., Kobayashi M., Tsuneoka K. Laparoscopic measurement of pancreatic blood flow. Endoscopy. 15:1983;107-110.
83. Kubo S., Yamamoto K., Magata Y., Iwasaki Y., Tamaki N., Yonekura Y., Konishi J. Assessment of pancreatic blood flow with positron emission tomography and oxygen-15 water. Ann. Nucl. Med. 5:1991;133-138.
84. Toyama M. T., Patel A. G., Kusske A., Bongard F. S., Ashley S. W., Reber H. A. Pancreatic tissue oxygenation in chronic pancreatitis. Pancreas. 9:1994;805.
85. Patel A. G., Toyama M. T., Alvarez C., Nguyen T. N., Reber P. U., Ashley S. W., Reber H. A. Pancreatic interstitial pH in human and feline chronic pancreatitis. Gastroenterology. 109:1995;1639-1645.
86. Yang H. Y., Liao J. F., Shum A. Y., Chen C. F. Regional differences of effects of ethanol on canine blood vessels. Artery. 14:1987;154-164.
87. Piano M., Holm K., Melchior C., Ferguson J. Alterations in splanchnic blood flow after low and high doses of ethanol. Alcohol Clin. Exp. Res. 15:1991;106-111.
88. Widdison A. L., Alvarez C., Schwarz M., Reber H. A. The influence of ethanol on pancreatic blood flow in cats with chronic pancreatitis. Surgery. 112:1992;202-208.
89. Toyama M. T., Patel A. G., Nguyen T., Ashley S. W., Reber H. A. Effect of ethanol on pancreatic interstitial pH and blood flow in cats with chronic pancreatitis. Ann. Surg. 225:1997;223-228.
90. Lewis M., Reber P., Kusske A., Toyama M., Reber H., Ashley S. Intragastric ethanol causes pancreatic endothelin release in the cat. Gastroenterology. 110:1996;A411.