Integration of filgrastim into chemoradiation for limited small cell lung cancer: A Phase I study

International Journal of Radiation Oncology Biology Physics

Volumn 40, Issue 2, 1998, Pages 331-336

  Glisson, Bonnie ^a   Komaki, Ritsuko ^a   Lee, Jin Soo ^a   Shin, Dong M ^a   Fossella, Frank ^a   Murphy, William K ^a   Kurie, Jonathan ^a   Perez Soler, Roman ^a   Schea, Randi ^a   Vadhan Raj, Saroj ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Chemoradiation; Cisplatin; Hematopoietic growth factors; Ifosfamide; Oral etoposide; Small cell lung cancer

Indexed keywords

CISPLATIN; ETOPOSIDE; IFOSFAMIDE; MESNA; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DRUG RESPONSE; ESOPHAGITIS; FEMALE; HEMATURIA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG FIBROSIS; LUNG SMALL CELL CANCER; MALE; MAXIMUM PERMISSIBLE DOSE; NAUSEA; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL; PNEUMONIA; PRIORITY JOURNAL; THROMBOCYTOPENIA; TREATMENT OUTCOME; VOMITING;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SMALL CELL; CISPLATIN; COHORT STUDIES; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; ETOPOSIDE; FEMALE; FEVER; FILGRASTIM; HUMANS; IFOSFAMIDE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEUTROPENIA; THROMBOCYTOPENIA;

EID: 0032518464     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00709-8     Document Type: Article

References (33)

1. 1. Bunn, P. A.; Lichter, A. S.; Makuch, R. W.; et al. Chemotherapy alone or chemotherapy with chest radiation therapy in limited stage small cell lung cancer. Ann. Intern. Med, 106: 655-662; 1987.
2. 2. Bunn, P. A.; Crowley, J.; Kelly, K.; et al. Chemoradiotherapy with or without granulocyte-macrophage colony-stimulating factor in the treatment of limited stage small cell lung cancer: A prospective phase III randomized study of the Southwest Oncology Group. J. Clin. Oncol. 13:1632-1641; 1995.
3. 3. Carlson, R. W.; Sikic, B. I.; Gandara, D. R.; et al. Late consolidative radiation therapy in the treatment of limited stage small cell lung cancer. Cancer 68:948-958; 1991.
4. 4. Crawford, J.; Ozer, H.; Stoller, R.; et al. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N. Engl. J. Med. 325:164-170; 1991.
5. 5. Einhorn, L. H.; Pennington, K.; McClean, J. Phase II trial of daily oral VP-16 in refractory small cell lung cancer: A Hoosier Oncology Group study. Semin. Oncol. 7:32-35; 1990.
6. 6. Fushiki, M.; Abe, M. Randomized double-blinded controlled study of rhG-CSF in patients with neutropenia induced by radiation therapy (Abstr). Proc. Am. Soc. Clin. Oncol. 11:410; 1992.
7. 7. Glisson, B.; Lee, J. S.; Palmer, J.; et al. Cisplatin, ifosfamide, and prolonged oral etoposide in extensive small cell lung cancer. Cancer (in press).
8. 8. Goodman, E. G.; Crowley, J.; Livingston, R. B.; et al. Treatment of limited small-cell lung cancer with concurrent etoposide/cisplatin and radiotherapy followed by intensification with high-dose cyclophosphamide: A Southwest Oncology Group study. J. Clin. Oncol. 9:453-457; 1991.
9. 9. Johnson, B. E.; Grayson, J.; Woods, E.; et al. Limited stage small cell lung cancer treated with concurrent etoposide/cisplatin plus bid chest radiotherapy (Abstr). Proc. Am. Soc. Clin. Oncol. 8:228; 1989.
10. 10. Johnson, D. H.; Greco, F. A.; Strupp, J.; et al. Prolonged administration of oral etoposide in patients with relapsed or refractory small cell lung cancer: A phase II trial. J. Clin. Oncol. 8:1613-1617.11; 1990.
11. 11. Johnson, D. H.; Bass, D.; Einhorn, L. H.; et al. Combination chemotherapy with or without thoracic radiotherapy in limited-stage small-cell lung cancer. A randomized trial of the Southeastern Cancer Study Group. J. Clin. Oncol. 11:1223-1229; 1993.
12. 12. Johnson, D. H.; Ki, K.; Turrisi, A. T.; et al. Cisplatin and etoposide plus concurrent thoracic radiotherapy administered once versus twice daily for limited stage small cell lung cancer. Preliminary results of an Intergroup Trial (Abstr). Proc. Am. Soc. Clin. Oncol. 13:333; 1994.
13. 13. Kaplan, E. L.; Meier, P. Non-parametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:457-481; 1958.
14. 14. Knox, S. J.; Fowler, S.; Marquez, C; et al. Effect of filgrastim (G-CSF) in Hodgkin's disease patients treated with radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 28:445-450; 1994.
15. 15. Lieschke, G. J.; Burgess, A. W. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. N. Engl. J. Med. 327:99-106; 1992.
16. 16. Loehrer, P. J.; Rynard, S.; Ansari, R.; et al. Etoposide, ifosfamide, and cisplatin in extensive small cell lung cancer. Cancer 69:669-673; 1992.
17. 17. Loehrer, P. J.; Ansari, R.; Gonin, R.; et al. Cisplatin plus etoposide with and without ifosfamide in extensive samll-cell lung cancer: A Hoosier Oncology Group study. J. Clin. Oncol. 13:2594-2599; 1995.
18. 18. MacManus, M. P.; Clarke, J.; McCormick, D.; et al. Use of recombinant granulocyte-colony stimulating factor to treat neutropenia occurring during craniospinal irradiation. Int. J. Radiat. Oncol. Biol. Phys. 26:845-850; 1993.
19. 19. Marks, L. B.; Friedman, H. S.; Kurtzberg, J.; et al. Reversal of radiation-induced neutropenia by granulocyte colony stimulating factor. Med. Pediatr. Oncol. 20:240-242; 1992.
20. 20. McCracken, J. D.; Janaki, L. M.; Crowley, J. J.; et al. Concurrent chemotherapy/radiotherapy for limited small-cell lung carcinoma: A Southwest Oncology Group study. J. Clin, Oncol. 8:892-898; 1990.
21. 21. Meropol, N. J.; Miller, L. L.; Korn, E. L.; et al. Severe myelosuppression resulting from concurrent administration of granulocyte colony-stimulating factor and cytotoxic chemotherapy. J. Natl. Cancer. Inst. 84:1201-1203; 1992.
22. 22. Miller, A. A.; Herndon, J. E.; Hollis, D. R.; et al. Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: A randomized phase III study of the Cancer and Leukemia Group B. J. Clin. Oncol. 13:1871-1879; 1995.
23. 23. Miller, A. B.; Hoogstraten, B.; Staquet, M. Reporting results of cancer treatment. Cancer 47:207-214; 1981.
24. 24. Momin, F.; Kraut, M.; Lattin, P.; et al. Thrombocytopenia in patients receiving chemotherapy and G-CSF for locally advanced non-small cell lung cancer (Abstr). Proc. Am. Soc. Clin. Oncol. 11:294; 1992.
25. 25. Murphy, P. B.; Hainsworth, J. D.; Greco, F. A.; et al. A phase II trial of cisplatin and prolonged administration of oral etoposide in extensive-stage small cell lung cancer. Cancer 69: 370-375; 1992.
26. 26. Murray, N.; Coy, P.; Pater, J. L.; et al. Importance of timing for thoracic irradiation in combined modality treatment of limited-stage small-cell lung cancer. J. Clin. Oncol. 11:336-344; 1993.
27. 27. Pignon, J. P.; Arrigada, R.; Ihde, D. C.; et al. A meta-analysis of thoracic radiotherapy for small cell lung cancer. N. Engl. J. Med. 327:1618-1624; 1992.
28. 28. Rowinsky, E.; Sartorious, S.; Grochow, L.; et al. Phase I and pharmacologic study of topotecan, an inhibitor of topoisomerase I, with granulocyte colony-stimulating factor: Toxicologic differences between concurrent and post-treatment G-CSF administration (Abstr.). Proc. Am. Soc. Clin. Oncol. 11:116; 1992.
29. 29. Schmidberger, H.; Hess, C. F.; Hoffmann, W.; et al. Granulocyte colony-stimulating factor treatment of leucopenia during fractioned radiotherapy. Eur. J. Cancer 29A:1927-1931; 1993.
30. 30. Turrisi, A. T.; Glover, D. J.; Mason, B. A. A preliminary report: Concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for limited small cell lung cancer. Int. J. Radiat. Biol. Phys. 15:183-187; 1988.
31. 31. Yokes, E. E.; Panje, W. R.; Schilsky, R. L.; et al. Hydroxyurea, 5-fluorouracil, and concomitant radiotherapy in poor prognosis head and neck cancer: A phase I-II study. J. Clin. Oncol. 7:761-768; 1989.
32. 32. Warde, P.; Payne, D. Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysis. J. Clin. Oncol. 10:890-895; 1992.
33. 33. Wolff, A. C.; Ettinger, D. S.; Neuberg, D.; et al. Phase II study of ifosfamide, carboplatin, and oral etoposide chemotherapy for extensive-disease small-cell lung cancer: An Eastern Cooperative Oncology Group pilot study. J. Clin. Oncol. 13: 1615-1622; 1995.