A GTP-dependent 'push' is generally required for efficient protein translocation across the mitochondrial inner membrane into the matrix

Journal of Biological Chemistry

Volumn 273, Issue 33, 1998, Pages 20941-20950

  Sepuri, Naresh Babu V ^a   Gordon, Donna M ^a   Pain, Debkumar ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL COMPARTMENTALIZATION; CELL ORGANELLE; GENE TARGETING; GENE TRANSLOCATION; MEMBRANE BINDING; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; FUNGAL PROTEINS; GUANOSINE TRIPHOSPHATE; INTRACELLULAR MEMBRANES; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; PROTEIN DENATURATION; SACCHAROMYCES CEREVISIAE; UREA;

EID: 0032516912     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.33.20941     Document Type: Article

References (51)

1. Schleyer, M., and Neupert, W. (1985) Cell 43, 339-350
2. Eilers, M., Oppliger, W., and Schatz, G. (1987) EMBO J. 6, 1073-1077
3. Martin, J., Mahlke, K., and Pfanner, N. (1991) J. Biol. Chem. 266, 18051-18057
4. Glick, B., Wachter, C., and Schatz, G. (1991) Trends Cell Biol. 1, 99-103
5. Pfanner, N., Rassow, J., van der Klei, I. J., and Neupert, W. (1992) Cell 68, 999-1002
6. Schülke, N., Sepuri, N. B. V., and Pain, D. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7314-7319
7. Mihara, K., and Omura, T. (1996) Trends. Cell Biol. 6, 104-108
8. Neupert, W. (1997) Annu. Rev. Biochem. 66, 863-917
9. Eilers, M., Hwang, S., and Schatz, G. (1988) EMBO J. 7, 1139-1145
10. Ostermann, J., Horwich, A. L., Neupert, W., and Hartl, F.-U. (1989) Nature 341, 125-130
11. Becker, K., Guiard, B., Rassow, J., Söllner, T., and Pfanner, N. (1992) J. Biol. Chem. 267, 5637-5643
12. Koll, H., Guiard, B., Rassow, J., Ostermann, J., Horwich, A. L., Neupert, W., and Hartl, F.-U. (1992) Cell 68, 1163-1175
13. Schneider, H.-C., Berthold, J., Bauer, M. F., Dietmeier, K., Guiard, B., Brunner, M., and Neupert, W. (1994) Nature 371, 768-774
14. Neupert, W., Hartl, F.-U., Craig, E. A., and Pfanner, N. (1990) Cell 63, 447-450
15. Glick, B. S. (1995) Cell 80, 11-14
16. Horst, M., Oppliger, W., Feifel, B., Schatz, G., and Glick, B. S. (1996) Protein Sci. 5, 759-767
17. Pfanner, N., and Neupert, W. (1986) FEBS Lett. 209, 152-156
18. Chen, W.-J., and Douglas, M. G. (1987) Cell 49, 651-658
19. Pfanner, N., Tropschug, M., and Neupert, W. (1987) Cell 49, 815-823
20. Hwang, S. T., and Schatz, G. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8432-8436
21. Wachter, C., Schatz, G., and Glick, B. S. (1994) Mol. Biol. Cell 5, 465-474
22. Sepuri, N. B. V., Schülke, N., and Pain, D. (1998) J. Biol. Chem. 273, 1420-1424
23. Ohba, M., and Schatz, G. (1987) EMBO J. 6, 2117-2122
24. Hwang, S., Jascur, T., Vestweber, D., Pon, L., and Schatz, G. (1989) J. Cell Biol. 109, 487-493
25. Murakami, H., Pain, D., and Blobel, G. (1988) J. Cell Biol. 107, 2051-2057
26. Craig, E. A., Kramer, J., Shilling, J., Werner-Washburne, M., Holmes, S., Kosic-Smithers, J., and Nicolet, C. M. (1989) Mol. Cell. Biol. 9, 3000-3008
27. Tokatlidis, K., Junne, T., Moes, S., Schatz, G., Glick, B. S., and Kronidou, N. (1996) Nature 384, 585-588
28. Schülke, N., Blobel, G., and Pain, D. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8011-8015
29. Murakami, H., Blobel, G., and Pain, D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3358-3362
30. Pain, D., Murakami, H., and Blobel, G. (1990) Nature 347, 444-449
31. Majima, E., Koike, H., Hong, Y.-M., Shinohara, Y., and Terada, H. (1993) J. Biol. Chem. 268, 22181-22187
32. Eilers, M., and Schatz, G. (1986) Nature 322, 228-232
33. Rassow, J., Hartl, F.-U., Guiard, B., Pfanner, N., and Neupert, W. (1990) FEBS Lett. 275, 190-194
34. Pfanner, N., Rassow, J., Guiard, B., Söllner, T., Hartl, F.-U., and Neupert, W. (1990) J. Biol. Chem. 265, 16324-16329
35. Tzagoloff, A. (1982) Mitochondria. Cellular Organelles Series (Siekevitz, P., Ed.), Plenum Press, New York
36. Stuart, R. A., Gruhler, A., van der Klei, I., Guiard, B., Koll, H., and Neupert, W. (1994) Eur. J. Biochem. 220, 9-18
37. Komiya, T., Sakaguchi, M., and Mihara, K. (1996) EMBO J. 15, 399-407
38. Matouschek, A., Azem, A., Ratliff, K., Glick, B. S., Schmid, K., and Schatz, G. (1997) EMBO J. 16, 6727-6736
39. Fukuchi, T., Nikawa, J., Kimura, N., and Watanabe, K. (1993) Gene (Amst.) 129, 141-146
40. Millman, J. S., and Andrews, D. W. (1997) Cell 89, 673-676
41. Olsen, L. J., and Keegstra, K. (1992) J. Biol. Chem. 267, 433-439
42. Soling, H.-D. (1982) Metabolic Compartmentation (Sies, H., ed) pp. 123-146, Academic Press, New York
43. Ziegler, M., Dubiel, W., Pimenov, A. M., Tikhonov, Y. V., Toguzov, R. T., Henke, W., and Gerber, G. (1989) FEBS Lett. 248, 182-184
44. Gasser, S. M., Daum, G., and Schatz, G. (1982) J. Biol. Chem. 257, 13034-13041
45. Majima, E., Yamaguchi, N., Chuman, H., Shinohara, Y., Ishida, M., Goto. S., and Terada, H. (1998) Biochemistry 37, 424-432
46. Wickner, W. T. (1994) Science 266, 1197-1198
47. Schekman, R. (1994) Cell 78, 911-913
48. Rapoport, T. A., Jungnickel, B., and Kutay, U. (1996) Annu. Rev. Biochem. 65, 271-303
49. Schnell, D. J. (1995) Cell 83, 521-524
50. Scott, S. V., and Theg, S. M. (1996) J. Cell Biol. 132, 63-75
51. Pain, D., and Blobel, G. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 3288-3292