GTP cyclohydrolase I inhibition by the prototypic inhibitor 2,4- diamino-6-hydroxypyrimidine: Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein

Journal of Biological Chemistry

Volumn 273, Issue 33, 1998, Pages 21091-21098

  Xie, Linjun ^a   Smith, Joseph A ^a   Gross, Steven S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; TETRAHYDROBIOPTERIN;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; ENZYME INDUCTION; ENZYME INHIBITORS; GTP CYCLOHYDROLASE; HYPOXANTHINES; MUSCLE, SMOOTH, VASCULAR; PHENYLALANINE; POLYMERASE CHAIN REACTION; PROTEINS; RATS; RNA, MESSENGER;

EID: 0032516897     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.33.21091     Document Type: Article

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