Heterogeneous expression and activity of endothelial and inducible nitric oxide synthases in end-stage human heart failure: Their relation to lesion site and β-adrenergic receptor therapy

Circulation

Volumn 98, Issue 2, 1998, Pages 132-139

  Fukuchi, Mitsumasa ^a   Hussain, Sabah N A ^a   Giaid, Adel ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

Biopsy; Cells; Immunohistochemistry; RNA

Indexed keywords

NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; FEMALE; HEART FAILURE; HEART MUSCLE CELL; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; MACROPHAGE; MALE; PRIORITY JOURNAL;

EID: 0032516491     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.98.2.132     Document Type: Article

References (32)

1. Hare JM, Colucci WS. Role of nitric oxide in the regulation of myocardial function. Prog Cardiovasc Dis. 1995;38:155-166.
2. Förstermann U, Closs EI, Pollock JS, Nakane M, Schwarz P, Gath I, Kleinen H. Nitric oxide synthase enzymes: characterization, purification, molecular cloning, and functions. Hypertension. 1994;23:1121-1131.
3. Kelly RA, Balligand J-L, Smith TW. Nitric oxide and cardiac function. Circ Res. 1996;79:363-380.
4. Brady AJB, Poole-Wilson PA, Harding SE, Warren JB. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol. 1992;263(Heart Circ Physiol 32):H1963-H1966.
5. Wildhirt SM, Dudek RR, Suzuki H, Pinto V, Narayan KS, Bing RJ. Immunohistochemistry in the identification of nitric oxide synthase isoenzymes in myocardial infarction. Cardiovasc Res. 1995;29:526-531.
6. Ishiyama S, Hiroe M, Nishikawa T, Abe S, Shimojo T, Ito H, Ozasa S, Yamakawa K, Matsuzaki M, Mohammed MU, Nakazawa H, Kasajima T, Marumo F. Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats. Circulation. 1997;95:489-496.
7. Yang X, Chowdhury N, Cai B, Brett J, Marboe C, Sciacca RR, Michler RE, Cannon PJ. Induction of myocardial nitric oxide synthase by cardiac allograft rejection. J Clin Invest. 1994;94:714-721.
8. Worrall NK, Pyo RT, Botney MD, Misko TP, Sullivan PM, Alexander DG, Lazenby WD, Ferguson TB. Inflammatory cell-derived NO modulates cardiac allograft contractile and electrophysiological function. Am J Physiol. 1997;273(Heart Circ Physiol 42):H28-H37.
9. de Beider AJ, Radomski MW, Why HJ, Richardson PJ, Martin JF. Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischemic or valvular heart disease. Br Heart J. 1995;74:426-430.
10. Habib FM, Springall DR, Davies GJ, Oakley CM, Yacoub MH, Polak JM. Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet. 1996;347:1151-1155.
11. Haywood GA, Tsao PS, von der Leyen HE, Mann MJ, Keeling PJ, Trindate PT, Lewis NP, Byrne CD, Rickenbacher PR, Bishopric NH, Cooke JP, McKenna WJ, Fowler MB. Expression of inducible nitricoxide synthase in human heart failure. Circulation. 1996;93:1087-1094.
12. Thoenes M, Förstermann U, Tracey WR, Bleese NM, Nüssler AK, Scholz H, Stein B. Expression of inducible nitric oxide synthase in failing and non-failing human heart. J Mol Cell Cardiol. 1996;28:165-169.
13. Yamamoto S, Tsutsui H, Tagawa H, Saito K, Takahashi M, Tada H, Yamamoto M, Katoh M, Egashira K, Takeshita A. Role of myocyte nitric oxide in β-adrenergic hyporesponsiveness in heart failure. Circulation. 1997;95:1111-1114.
14. Belhassen L, Kelly RA, Smith TW, Balligand J-L. Nitric oxide synthase (NOS3) and contractile responsiveness to adrenergic and cholinergic agonists in the heart: regulation of NOS3 transcription in vitro and in vivo by cyclic adenosine monophosphate in rat cardiac myocytes. J Clin Invest. 1996;97:1908-1915.
15. Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med. 1995;333:214-221.
16. Hussain SNA, Giaid A, Dawiri QEI, Sakkal D, Hattori R, Guo Y. Expression of nitric oxide synthase and GTP cyclohydrolase I in the ventilatory and limb muscles during endotoxemia. Am J Respir Cell Mol Biol. 1997;17:173-180.
17. Balligand J-L, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA. 1993;90:347-351.
18. Balligand J-L, Ungureanu-Longrois D, Simmons WW, Pimental D, Malinski TA, Kapturczak M, Taha Z, Lowenstein CJ, Davidoff AJ, Kelly RA, Smith TW, Michel T. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. J Biol Chem. 1994;269: 27580-27588.
19. Beau SL, Tolley TK, Saffitz JE. Heterogeneous transmural distribution of β-adrenergic receptor subtypes in failing human hearts. Circulation. 1993;88:2501-2509.
20. Danielsen W, v. der Leyen H, Meyer W, Neumann J, Schmitz W, Scholz H, Starbatty J, Stein B, Döring V, Kalmár P. Basal and isoprenaline-stimulated cAMP content in failing versus nonfailing human cardiac preparations. J Cardiovasc Phannacol. 1989;14:171-173.
21. Böhm M, Reiger B, Schwinger RHG, Erdmann E. cAMP concentrations. cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium. Cardiovasc Res. 1994;28:1713-1719.
22. 2-adrenergic stimulation. Circulation. 1995;92:1612-1618.
23. 1-receptor down-regulation in heart failure. Circ Res. 1986;59:297-309.
24. Baker JE, Holman P, Kalyanaraman B, Pritchard KA. Chronic myocardial hypoxia increases eNOS expression to produce elevated levels of nitric oxide for cardioprotection. Circulation. 1996;94(suppl I):I-468. Abstract.
25. Ikeda U, Yamamoto K, Kanbe T, Kawahara Y, Shimada K. Adrenomedullin augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes. Circulation. 1996;94(suppl I):I-700. Abstract.
26. Matsumori A, Yamada T, Suzuki H, Matoba Y, Sasayama S. Increased circulating cytokines in patients with myocarditis and cardiomyopathy. Br Heart J. 1994;72:561-566.
27. Torre-Amione G, Kapadia S, Lee J, Durand J-B, Bies RD, Young JB, Mann DL. Tumor necrosis factor-α and tumor necrosis factor receptors in the failing human heart. Circulation. 1996;93:704-711.
28. Hokimoto S, Yasue H, Fujimoto K, Sakata R, Miyamoto E. Increased angiotensin converting enzyme activity in left ventricular aneurysm of patients after myocardial infarction. Cardiovasc Res. 1995;29:664-669.
29. Jougasaki M, Rodeheffer RJ, Redfield MM, Yamamoto K, Wei C-M, McKinley LJ, Burnett JC Jr. Cardiac secretion of adrenomedullin in human heart failure. J Clin Invest. 1996;97:2370-2376.
30. Pinsky DJ, Cai B, Yang X, Rodriguez C, Sciacca RR, Cannon PJ. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor. J Clin Invest. 1995;95:677-685.
31. Szabó C, Day BJ, Salzman AL. Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Lett. 1996;381:82-86.
32. Ishida H, Ichimori K, Hirota Y, Fukahori M, Nakazawa H. Peroxynitrite-induced cardiac myocyte injury. Free Radic Biol Med. 1996;20:343-350.