Probing catalytic hinge bending motions in thermolysin-like proteases by Glycine → Alanine mutations

Biochemistry

Volumn 37, Issue 15, 1998, Pages 5305-5311

  Veltman, Oene R ^a   Eijsink, Vincent G H ^b   Vriend, Gert ^c   De Kreij, Arno ^a   Venema, Gerard ^a   Van Den Burg, Bertus ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BACTERIAL ENZYME; GLYCINE; MEMBRANE METALLOENDOPEPTIDASE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ENZYME STRUCTURE; GENE MUTATION; GEOBACILLUS STEAROTHERMOPHILUS; NONHUMAN; PRIORITY JOURNAL;

ALANINE; AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BACTERIAL PROTEINS; BINDING SITES; DNA MUTATIONAL ANALYSIS; ENZYME STABILITY; GLYCINE; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTION; MUTAGENESIS, SITE-DIRECTED; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS); FELIS CATUS; GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0032515911     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972374j     Document Type: Article

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