Homocysteine-dependent alterations in mitochondrial gene expression, function and structure: Homocysteine and H2O2 act synergistically to enhance mitochondrial damage

Journal of Biological Chemistry

Volumn 273, Issue 46, 1998, Pages 30808-30817

  Austin, R C ^a   Sood, S K ^a   Dorward, A M ^a   Singh, G ^a   Shaughnessy, S G ^a   Pamidi, S ^a   Outinen, P A ^a   Weitz, J I ^a  

^a HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COMPLEMENTARY DNA; COPPER ION; CYTOCHROME C OXIDASE; GLUTATHIONE; HOMOCYSTEINE; HYDROGEN PEROXIDE; MESSENGER RNA;

AORTA; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE STRUCTURE; HUMAN; HUMAN CELL; HYPERHOMOCYSTEINEMIA; LIVER CELL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; PRIORITY JOURNAL; RESPIRATORY CHAIN;

ANIMALS; BLOTTING, NORTHERN; CELL LINE; CELL SURVIVAL; CHAPERONIN 60; COPPER; DNA, MITOCHONDRIAL; DRUG SYNERGISM; FREE RADICALS; GENE EXPRESSION; HOMOCYSTEINE; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; OXYGEN CONSUMPTION; RATS; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032515179     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.46.30808     Document Type: Article

References (40)