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Volumn 63, Issue 23, 1998, Pages 8133-8144

Synthesis of methylene-expanded 2',3'-dideoxyribonucleosides

Author keywords

[No Author keywords available]

Indexed keywords

LEVOGLUCOSENONE 8; NUCLEOSIDE ANALOG; RIBONUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0032514984     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980436l     Document Type: Article
Times cited : (24)

References (50)
  • 26
    • 15444339721 scopus 로고    scopus 로고
    • note
    • (l) Although levoglucosenone is commercially available from Yuki Kogyo Co., Ltd., we conducted all our experiments on "self-made" material, prepared by pyrolysis of acid-treated newspaper or cellulose.
  • 39
    • 0001164165 scopus 로고    scopus 로고
    • Trost, B. M,; Shi, Z. J. Am. Chem. Soc. 1996, 118, 3037. Ukai, T.; Kawazura, H.; Ishii, Y.; Bonnet, J. J.; Ibers, J. A. J. Organomet. Chem. 1974, 65, 253.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 3037
    • Trost, B.M.1    Shi, Z.2
  • 43
  • 48
    • 15444352165 scopus 로고    scopus 로고
    • note
    • Some transfer of the acetate functionality from the 2-to the 3-hydroxyl occurred in this step as well as partial hydrolysis to the diol.
  • 49
    • 15444346523 scopus 로고    scopus 로고
    • note
    • We believe that the less hindered hydroxyl group at C-2 could be selectively protected to allow deoxygenation at C-3 and then an application of the synthesis described for 7a to the resulting azido alcohol would afford the ring-expanded AZT analogue.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.