Increased QT dispersion and other repolarization abnormalities as a possible cause of electrical instability in isolated aortic stenosis

International Journal of Cardiology

Volumn 64, Issue 1, 1998, Pages 57-62

  Ducceschi, V ^a   Sarubbi, B ^a   D'Andrea, A ^a   Liccardo, B ^a   Briglia, N ^a   Carozza, A ^a   Marmo, J ^a   Santangelo, L ^a   Iacono, A ^a   Cotrufo, M ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Aortic stenosis; Pressure gradients; QT dispersion; Repolarization

Indexed keywords

ADULT; AGED; AORTA DISEASE; AORTA STENOSIS; ARRHYTHMOGENESIS; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; DOPPLER ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HEART ARRHYTHMIA; HEART REPOLARIZATION; HUMAN; MALE; PRESSURE GRADIENT; PRIORITY JOURNAL; QT INTERVAL;

ADULT; AGED; AORTIC VALVE STENOSIS; ECHOCARDIOGRAPHY, DOPPLER; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; PROGNOSIS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX;

EID: 0032513190     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(97)00334-3     Document Type: Article

References (36)

1. Keane J.F., Driscoll D.J., Gersony W.M., Hayes C.J., Kidd L., O'Fallon M., Pieroni D.R., Wolfe R.R., Weidman W.H. Second Natural History Study of Congenital Heart Defects. Results of treatment of patients with aortic valvar stenosis. Circulation. 87(Suppl. I):1993;16-27.
2. Wolfe R.R., Driscoll D.J., Gersony W.M., Hayes C.J., Keane J.F., Kidd L., O'Fallon M., Pieroni D.R., Weidman W.H. Arrhythmias in patients with valvar aortic stenosis, valvar pulmonary stenosis and ventricular septal defect. Result of 24-hour ECG monitoring. Circulation. 87(Suppl 1):1993;89-101.
3. Selzer, S., Lombard, J.T., Clinical findings in adult aortic stenosis - then and now. Eur. Heart J. 1988; Suppl. E: 53-5.
4. Klein R. Ventricular arrhythmias in aortic valve disease. Analysis of 102 patients. Am. J. Cardiol. 53:1984;1079-1083.
5. De Finis A., Di Napoli P., Gaeta M.A., Gaeta F., Gallina S., Gallina A., Calafiore A.M., Trevi G., Barsotti A. Caratteristiche ed evoluzione clinica della stenosi aortica degenerativa senile. Cardiologia. 40:1995;101-107.
6. Sorgato A., Faggiano P., Simoncell U., Rusconi C. Prevalence of late potentials in adult aortic stenosis. Int. J. Cardiol. 53:1996;55-59.
7. Day C.P., McComb J.M., Campbell R.W.F. QT dispersion: an indication of arrhythmia risk in patients with long QT intervals. Br. Heart J. 63:1990;342-344.
8. Day C.P., McComb J.M., Matthews J., Campbell R.F. Reduction in QT dispersion by sotalol following myocardial infarction. Eur. Heart J. 12:1991;423-427.
9. Pye M.P., Quinn A.C., Cobbe S.M. QT interval dispersion: a non-invasive marker of susceptibility to arrhythmia in patients with sustained ventricular arrhythmias? Br. Heart J. 71:1994;511-514.
10. Higham P.D., Campbell R.W.F. QT dispersion. Br. Heart J. 71:1994;508-510.
11. Zareba V., Moss A.J., le Cessie S. Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary artery disease. Am. J. Cardiol. 74:1994;550-553.
12. Zabel M., Portnoy S., Franza M.R. Electrocardiographic indexes of dispersion of ventricular repolarization: an isolated heart validation study. J. Am. Coll. Cardiol. 25:1995;746-752.
13. Perkiomaki J.S., Koistinen M.J., Yli-Mayry S., Huikuri H.V. Dispersion of QT interval in patients with and without susceptibility to ventricular tachyarrhythmias after previous myocardial infarction. J. Am. Coll. Cardiol. 26:1995;174-179.
14. Sarubbi B., Ducceschi V., Briglia N., Esposito R., Mayer M.S., Scialdone A., Santangelo L., Iacono A. Sotalolo, propafenone e flecainide: analisi comparata multiparametrica della ripolarizzazione ventricolare in soggetti esenti da cardiopatie organiche. Cardiologia. 41:1996;645-651.
15. Bogun F., Chan K.K., Harvey M., Goyal R., Castellani M., Niebauer M., Daoud E., Man K.C., Strickberger S.A., Morady F. QT dispersion in nonsustained ventricular tachycardia and coronary artery disease. Am. J. Cardiol. 77:1996;256-259.
16. Sarubbi B., Esposito V., Ducceschi V., Meoli B., Grella E., Santangelo L., Iacono A., Caputi M. Effect of blood gas derangement on QTc dispersion in severe chronic obstructive pulmonary disease: evidence of an electropathy? Int. J. Cardiol. 58:1997;287-292.
17. Okishige K., Yamashita K., Yoshinaga H., Azegami K., Satoh T., Goseki Y., Fujii S., Ohira H., Satake S. Electrophysiologic effects of ischemic preconditioning on QT dispersion during coronary angioplasty. J. Am. Coll. Cardiol. 28:1996;70-73.
18. Ducceschi V., Sanzbbi B., Giasi A., Russo B., Lucca P., Santangelo L., Giasi M., Iacono A. Correlation between late potentials duration and QTc dispersion: is there a causal relationship? Int. J. Cardiol. 53:1996;285-290.
19. Yuan S., Blomstrom-Lunqvist C., Pehrson S., Pripp C.M., Wohlfart B., Olsson S.B. Dispersion of repolarization following double and triple programmed stimulation. Eur. Heart J. 17:1996;1080-1091.
20. Nishimura R.A., Pieroni D.R., Bierrnan F.Z., Colan S.D., Kaufman S., Sanders S.P., Seward J.B., Tajik A.J., Wiggins J.W., Zahka K.G. Second Natural History Study of Congenital Heart Defects. Aortic stenosis: echocardiography. Circulation. 87(Suppl. I):1993;66-72.
21. Skjaerpe T., Hegrenaes L., Hatle L. Noninvasive estimation of valve area in patients with aortic stenosi by Doppler ultrasound and two-dimensional echocardiography. Circulation. 73:1986;452-459.
22. Rapaport, E., Rackley, C.E., Cahn, L.H. Aortic valve disease. In: Hurst's The Heart. 8th edition. Schlant, R.C. and Alexander, R.W. (Eds.) McGraw-Hill, New York, 1994:1457-81.
23. Schlant, R.C., Sonnenblick, E.H. Pathophysiology of heart failure. In: Hurst's The Heart. 8th edition. Schlant, R.C. and Alexander, R.W. (Eds.) McGraw-Hill, New York, 1994:515-55.
24. Hart G. Cellular electrophysiology in: cardiac hypertrophy and failure. Cardiovasc. Res. 28:1994;933-946.
25. Cameran J.S., Myerburg R.J., Wong S.S. Electrophysiological consequences of chronic experimentally induced left ventricular pressure overload. J. Am. Coll. Cardiol. 2:1983;481-487.
26. Capasso J.M., Malhotra A., Scheuer J., Sonnenblick E.H. Myacardial biochemical, contractile and electrical performance after imposition of hypertension in young and old rats. Circ. Res. 58:1986;445-460.
27. Schouten V.J.A., Vliegen H.W., van der Laarse A., Huysmans H.A. Altered calcium handling at normal contractility in hypertrophied rat heart. J. Mol. Cell Cardiol. 22:1990;987-998.
28. Pye M.P., Cobbe S.M. Mechanisms of ventricular arrhythmias in cardiac failure and hypertrophy. Cardiovasc. Res. 26:1992;740-750.
29. Barr C.B., Naas A., Freeman M., Lang C.C., Struthers A. QT dispersion and sudden unexpected death in chronic heart failure. Lancet. 343:1994;327-329.
30. Fu G.S., Meissner A., Simon R. Repolarization dispersion and sudden cardiac death in patients with impaired left ventricular function. Eur. Heart J. 18:1997;281-289.
31. Balanescu S., Galinier M., Fourcadt J., Dorobantu M., Albenque J.P., Massabuau P., Fauvel J.M., Bounhoure J.P. Correlation entre la dispersion de l' intervalle QT et les arythmies ventriculaires dans l' hypertension arterielle. Arch. Mal. Coeur. 89:1996;987-990.
32. Morganroth J. Relations of QTc prolongation on the electrocardiogram to torsades de pointes. Definitions and mechanisms. Am. J. Cardiol. 72:1993;10B-13B.
33. Zipes D.P. The long QT syndrome: a Rosetta stone for sympathetic related ventricular tachyarrhythmias. Circulation. 84:1991;1414-1419.
34. Jackman V.M., Szabo B., Friday K.J., Margolis P.D., Moulton K., Wang X., Patterson E., Lazzara R. Ventricular tachyarrhythmias related to early after depolarizations and triggered firing: relationship to QT interval prolongation and potential therapeutic role for calcium channel blocking agents. J. Cardiovasc. Electrophysiol. 1:1990;170-195.
35. Hii J.T.Y., Wyse G., Gillis A.M., Duff H.J., Solylo M.A., Mitchell L.B. Precordial QT interval dispersion as a marker of torsades de pointes: disparate effects of class IA antiarrhythmic drugs and amiodarone. Circulation. 86:1992;1376-1382.
36. Author, please supply.