Treatment of isolated systolic hypertension in the elderly: Further evidence from the Systolic Hypertension in Europe (Syst-Eur) trial

American Journal of Cardiology

Volumn 82, Issue 9 SUPPL. 1, 1998, Pages 20-22

  Staessen, Jan A ^a,b   Thijs, Lutgarde ^a   Gasowski, Jerzy ^a   Cells, Hilde ^a   Fagard, Robert H ^a  

^a KU LEUVEN DEPARTMENT OF REHABILITATION SCIENCES   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ANTAGONIST; DIHYDROPYRIDINE; ENALAPRIL PLUS HYDROCHLOROTHIAZIDE; NITRENDIPINE; PLACEBO;

ADULT; AGED; AGING; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; DOUBLE BLIND PROCEDURE; EUROPE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; STROKE; SYSTOLIC BLOOD PRESSURE; SYSTOLIC HYPERTENSION;

ADULT; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNEL BLOCKERS; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; DIABETES COMPLICATIONS; EUROPE; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; SYSTOLE; TREATMENT OUTCOME;

EID: 0032511970     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(98)00752-8     Document Type: Article

References (7)

1. Staessen J, Amery A, Fagard R. Isolated systolic hypertension in the elderly. J Hypertens 1990;8:393-405.
2. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991;265: 3255-3264.
3. Amery A, Birkenhager W, Bulpitt CJ, Clement D, De Leeuw P, Dollery CT, Fagard R, Fletcher A, Forette F, Leonetti G, et al. Syst-Eur. A multicentre trial on the treatment of isolated systolic hypertension in the elderly: objectives, protocol and organization. Aging Clin Exp Res 1991;3:287-302.
4. Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Birkenhager WH, Bulpitt CJ, de Leeuw PW, Dollery CT, Fletcher AE, Forette F, Leonetti G, Nachev C, O'Brien ET, Rosenfeld J, Rodicio JL, Tuomilehto J, Zanchetti A. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997;350:757-764 (correction in Lancet 1997;350:1636).
5. Staessen JA, Fagard R, Thijs L, Celis H, Birkenhager WH, Bulpitt CJ, de Leeuw PW, Fletcher AE, Babarskiene MR, Forette F, Kocemba J, Laks T, Leonetti G, Nachev C, Petrie JC, Tuomilehto J, Vanhanen H, Webster J, Yodfat Y, Zanchetti A. Subgroup and per-protocol analysis of the randomized European Trial on Isolated Systolic Hypertension in the Elderly. Arch Intern Med 1998; 158:1681-1691.
6. Tuomilento J, Rastenyte D, Birkenhäger WH, Staessen JA, Thijs L, Antikainen R, Bulpitt CJ, Fagard R, Fletcher A, Forette F, Palatini P, Sarti C, for the Systolic Hypertension in Europe (SystiEur) Trial Investigators. Cardiovascular prognosis in older diabetic and nondiabetic patients treated or untreated for isolated systolic hypertension. Submitted for publication.
7. Staessen JA, Thijs L, Fagard RH, Birkenhäger WH, Arabidze G, Babeanu S, Gil-Extremera B, Bulpitt CJ, Davidson C, de Leeuw PW, Efstratopoulos AD, Fletcher AE, Fogari R, Jääskivi M, Kawecka-Jaszcz K, Nachev C, Petrie JC, Seux M-L, Tuomilehto J, Webster J, Yodfat Y, for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Calcium channel blockade and cardiovascular prognosis in the European trial on isolated systolic hypertension. Hypertension 1998;32:410-416.