메뉴 건너뛰기




Volumn 421, Issue 1, 1998, Pages 109-116

Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine

Author keywords

5 Azacytidine; DNA damage; Topoisomerase inhibitor

Indexed keywords

AMSACRINE; AZACITIDINE; CAMPTOTHECIN; DNA TOPOISOMERASE INHIBITOR;

EID: 0032511823     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00162-6     Document Type: Article
Times cited : (7)

References (43)
  • 1
    • 0017082530 scopus 로고
    • 5-Azacytidine: A new anticancer drug with efectiveness in acute myelogenous leukaemia
    • [1] D. Von Hoff, M. Slavik, F. Muggia, 5-Azacytidine: a new anticancer drug with efectiveness in acute myelogenous leukaemia, Annu. Int. Med. 85 (1976) 237-245.
    • (1976) Annu. Int. Med. , vol.85 , pp. 237-245
    • Von Hoff, D.1    Slavik, M.2    Muggia, F.3
  • 2
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • [2] P.A. Jones, S.M. Taylor, Cellular differentiation, cytidine analogs and DNA methylation, Cell 20 (1980) 85-93.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 3
    • 0022545498 scopus 로고
    • DNA methylation affects the formation of active chromatin
    • [3] I. Keshet, J. Lieman-Hurwitz, H. Cedar, DNA methylation affects the formation of active chromatin, Cell 44 (1986) 535-543.
    • (1986) Cell , vol.44 , pp. 535-543
    • Keshet, I.1    Lieman-Hurwitz, J.2    Cedar, H.3
  • 4
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • [4] A. Bird, The essentials of DNA methylation, Cell 70 (1992) 5-8.
    • (1992) Cell , vol.70 , pp. 5-8
    • Bird, A.1
  • 5
    • 0021234241 scopus 로고
    • Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocytes and fibroblast cultures
    • [5] D.A. Shafer, J.H. Priest, Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocytes and fibroblast cultures, Am. J. Hum. Genet. 36 (1984) 534-545.
    • (1984) Am. J. Hum. Genet. , vol.36 , pp. 534-545
    • Shafer, D.A.1    Priest, J.H.2
  • 6
    • 0022351169 scopus 로고
    • DNA hypomethylation causes an increase in Dnase-I sensitivity and an advance in the time of replication of the entire inactive X chromosome
    • [6] E. Jablonka, R. Goitein, M. Marcus, H.C. Cedar, DNA hypomethylation causes an increase in Dnase-I sensitivity and an advance in the time of replication of the entire inactive X chromosome, Chromosoma 93 (1985) 152-156.
    • (1985) Chromosoma , vol.93 , pp. 152-156
    • Jablonka, E.1    Goitein, R.2    Marcus, M.3    Cedar, H.C.4
  • 7
    • 0023093867 scopus 로고
    • 5-aza-C-induced changes in the time of replication of the X chromosomes of Microtus agrestis are followed by non-random reversion to a late pattern of replication
    • [7] E. Jablonka, R. Goitein, K. Speclinas, H. Cedar, M. Marcus, 5-aza-C-induced changes in the time of replication of the X chromosomes of Microtus agrestis are followed by non-random reversion to a late pattern of replication, Chromosoma 95 (1987) 81-88.
    • (1987) Chromosoma , vol.95 , pp. 81-88
    • Jablonka, E.1    Goitein, R.2    Speclinas, K.3    Cedar, H.4    Marcus, M.5
  • 8
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • [8] E. Li, T. Bestor, R. Jaenisch, Targeted mutation of the DNA methyltransferase gene results in embryonic lethality, Cell 69 (1992) 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.2    Jaenisch, R.3
  • 9
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • [9] H. Leonhardt, A. Page, H. Weier, T. Bestor, A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei, Cell 71 (1992) 865-873.
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.2    Weier, H.3    Bestor, T.4
  • 11
    • 0021891888 scopus 로고
    • DNA topoisomerases
    • [11] J.C. Wang, DNA topoisomerases, Annu. Rev. Biochem. 54 (1985) 665-697.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 665-697
    • Wang, J.C.1
  • 12
    • 0025133118 scopus 로고
    • Involvement of nucleic acid synthesis in cell killing mechanism of topoisomerase poisons
    • [12] P. D'Arpa, C. Beardmore, L.F. Liu, Involvement of nucleic acid synthesis in cell killing mechanism of topoisomerase poisons, Cancer Res. 51 (1990) 6919-6924.
    • (1990) Cancer Res. , vol.51 , pp. 6919-6924
    • D'Arpa, P.1    Beardmore, C.2    Liu, L.F.3
  • 13
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumour drugs
    • [13] L.H.C. Liu, DNA topoisomerase poisons as antitumour drugs, Annu. Rev. Biochem. 58 (1989) 351-375.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.H.C.1
  • 14
    • 0025407684 scopus 로고
    • DNA topoisomerase dysfunction: A new goal for antitumor chemotherapy
    • [14] P.J. Smith, DNA topoisomerase dysfunction: a new goal for antitumor chemotherapy, BioEssays 12 (1990) 167-172.
    • (1990) BioEssays , vol.12 , pp. 167-172
    • Smith, P.J.1
  • 15
    • 0025276858 scopus 로고
    • A model for tumor cell killing by topoisomerase poisons
    • [15] H. Zhang, P. D'Arpa, L.F. Liu, A model for tumor cell killing by topoisomerase poisons, Cancer Cells 2 (1990) 23-27.
    • (1990) Cancer Cells , vol.2 , pp. 23-27
    • Zhang, H.1    D'Arpa, P.2    Liu, L.F.3
  • 16
    • 0027260350 scopus 로고
    • Cytogenetic effects of inhibition of topoisomerase I or II activities in the CHO mutant EM9 and its parental line AA8
    • [16] F. Cortés, J. Piñero, F. Paliti, Cytogenetic effects of inhibition of topoisomerase I or II activities in the CHO mutant EM9 and its parental line AA8, Mutat. Res. 288 (1993) 281-289.
    • (1993) Mutat. Res. , vol.288 , pp. 281-289
    • Cortés, F.1    Piñero, J.2    Paliti, F.3
  • 17
    • 0024420685 scopus 로고
    • Arrest of replication forks by drugs-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • [17] Y.-H. Hsiang, M.G. Lihon, L.F. Liu, Arrest of replication forks by drugs-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin, Cancer Res. 49 (1989) 5077-5082.
    • (1989) Cancer Res. , vol.49 , pp. 5077-5082
    • Hsiang, Y.-H.1    Lihon, M.G.2    Liu, L.F.3
  • 18
    • 0024388737 scopus 로고
    • Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells
    • [18] C. Holm, J.M. Covey, D. Kerrigan, Y.C. Pommier, Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells, Cancer Res. 49 (1989) 6365-6368.
    • (1989) Cancer Res. , vol.49 , pp. 6365-6368
    • Holm, C.1    Covey, J.M.2    Kerrigan, D.3    Pommier, Y.C.4
  • 19
    • 0027432215 scopus 로고
    • Importance of replication fork progression for the induction of chromosome damage and SCE by inhibitors of DNA topoisomerases
    • [19] F. Cortés, J. Piñero, T. Ortiz, Importance of replication fork progression for the induction of chromosome damage and SCE by inhibitors of DNA topoisomerases, Mutat. Res. 303 (1993) 71-76.
    • (1993) Mutat. Res. , vol.303 , pp. 71-76
    • Cortés, F.1    Piñero, J.2    Ortiz, T.3
  • 20
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo-and-5-iododeoxyuridine, a new reagent for detection of DNA replication
    • [20] H.G. Graztner, Monoclonal antibody to 5-bromo-and-5-iododeoxyuridine, a new reagent for detection of DNA replication, Science 218 (1982) 474-475.
    • (1982) Science , vol.218 , pp. 474-475
    • Graztner, H.G.1
  • 22
    • 0019867969 scopus 로고
    • Protein-associated deoxyribonucleic acid strand breaks in LIZ 10 cells treated with the deoxy ribonucleic acid intercalating agents 4′-(9-accydinylamino)-methanesulfon-m-anisidide and adriamycin
    • [22] L.A. Zwelling, S. Michaels, L.C. Erickson, R.S. Ungerleider, M. Nichols, K.W. Kohn, Protein-associated deoxyribonucleic acid strand breaks in LIZ 10 cells treated with the deoxy ribonucleic acid intercalating agents 4′-(9-accydinylamino)-methanesulfon-m-anisidide and adriamycin, Biochemistry 20 (1981) 6553-6563.
    • (1981) Biochemistry , vol.20 , pp. 6553-6563
    • Zwelling, L.A.1    Michaels, S.2    Erickson, L.C.3    Ungerleider, R.S.4    Nichols, M.5    Kohn, K.W.6
  • 23
    • 0021884675 scopus 로고
    • In vivo mapping of DNA topoisomerase II-specific cleavage sites in SV40 chromatin
    • [23] L. Yanes, T.C. Rowe, E.M. Nelson, L.F. Liu, In vivo mapping of DNA topoisomerase II-specific cleavage sites in SV40 chromatin, Cell 41 (1985) 127-132.
    • (1985) Cell , vol.41 , pp. 127-132
    • Yanes, L.1    Rowe, T.C.2    Nelson, E.M.3    Liu, L.F.4
  • 24
    • 0022514876 scopus 로고
    • Isolation of intercalator dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II
    • [24] J. Minford, Y. Pommier, J. Filipskis, K.W. Kohn, D. Kerrigan, M. Mattrn, S. Michaels, R. Schwartz, L.A. Zwelling, Isolation of intercalator dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II, Biochemistry 25 (1986) 9-16.
    • (1986) Biochemistry , vol.25 , pp. 9-16
    • Minford, J.1    Pommier, Y.2    Filipskis, J.3    Kohn, K.W.4    Kerrigan, D.5    Mattrn, M.6    Michaels, S.7    Schwartz, R.8    Zwelling, L.A.9
  • 25
    • 0000536643 scopus 로고
    • DNA topoisomerase can be studied in yeast
    • [25] J.L. Nitiss, J.C. Wang, DNA topoisomerase can be studied in yeast, Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 7501-7505.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 7501-7505
    • Nitiss, J.L.1    Wang, J.C.2
  • 26
    • 0027473372 scopus 로고
    • Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drugs-stimulated DNA cleavage in vitro
    • [26] Y.-H. Man, M.J.F. Dustin, Y. Pommier, L.F. Povirk, Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drugs-stimulated DNA cleavage in vitro, J. Mol. Biol. 229 (1993) 52-66.
    • (1993) J. Mol. Biol. , vol.229 , pp. 52-66
    • Man, Y.-H.1    Dustin, M.J.F.2    Pommier, Y.3    Povirk, L.F.4
  • 27
    • 0025980036 scopus 로고
    • Chromosome recombination and defective genome segregation induced in Chinese hamster cells by the topoisomerase II inhibitor VH-26
    • [27] M. Charron, R. Hancock, Chromosome recombination and defective genome segregation induced in Chinese hamster cells by the topoisomerase II inhibitor VH-26, Chromosoma 100 (1991) 97-102.
    • (1991) Chromosoma , vol.100 , pp. 97-102
    • Charron, M.1    Hancock, R.2
  • 28
    • 0024507201 scopus 로고
    • The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II: I. m-AMSA
    • [28] H.C. Anderson, B.A. Kihlman, The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II: I. m-AMSA, Carcinogenesis 10 (1989) 123-130.
    • (1989) Carcinogenesis , vol.10 , pp. 123-130
    • Anderson, H.C.1    Kihlman, B.A.2
  • 29
    • 0024355087 scopus 로고
    • Differential effects of 5-azacytidine and 5-azadeoxycytidine on cytotoxicity, DNA-strand breaking and repair of X-ray-induced DNA damage in Hela cells
    • [29] R.D. Snyder, P.J. Lackmann, Differential effects of 5-azacytidine and 5-azadeoxycytidine on cytotoxicity, DNA-strand breaking and repair of X-ray-induced DNA damage in Hela cells, Mutat. Res. 226 (1989) 185-190.
    • (1989) Mutat. Res. , vol.226 , pp. 185-190
    • Snyder, R.D.1    Lackmann, P.J.2
  • 30
    • 0025006831 scopus 로고
    • DNA repair in radiation sensitive mutants of mammalian cells: Possible involvement of DNA topoisomerases
    • [30] I.D. Hickson, S.L. Davies, S.M. Davies, C.N. Robson, DNA repair in radiation sensitive mutants of mammalian cells: possible involvement of DNA topoisomerases, Int. J. Radiat. Biol. 58 (1990) 561-568.
    • (1990) Int. J. Radiat. Biol. , vol.58 , pp. 561-568
    • Hickson, I.D.1    Davies, S.L.2    Davies, S.M.3    Robson, C.N.4
  • 31
    • 0014852258 scopus 로고
    • Comparison of lethality and chromosome damage induced by X-rays in synchronised chinese hamster cells in vitro
    • [31] W.C. Dewey, S.C. Furman, H.H. Miller, Comparison of lethality and chromosome damage induced by X-rays in synchronised chinese hamster cells in vitro, Radiat. Res. 43 (1970) 561-581.
    • (1970) Radiat. Res. , vol.43 , pp. 561-581
    • Dewey, W.C.1    Furman, S.C.2    Miller, H.H.3
  • 32
    • 0020064209 scopus 로고
    • X-ray induced chromosome damage in live mammalian cells and impaired measurements of its effects on their colony forming ability
    • [32] G.P. Joshi, W.J. Nelson, S.H. Revel, C.A. Shaw, X-ray induced chromosome damage in live mammalian cells and impaired measurements of its effects on their colony forming ability, Int. J. Radiat. Biol. 41 (1982) 161-181.
    • (1982) Int. J. Radiat. Biol. , vol.41 , pp. 161-181
    • Joshi, G.P.1    Nelson, W.J.2    Revel, S.H.3    Shaw, C.A.4
  • 33
    • 0023158059 scopus 로고
    • Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26)
    • [33] M.K. Dansk, J.C. Yalowic, W.T. Beck, Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26), Cancer Res. 47 (1987) 1297-1301.
    • (1987) Cancer Res. , vol.47 , pp. 1297-1301
    • Dansk, M.K.1    Yalowic, J.C.2    Beck, W.T.3
  • 34
    • 0024456572 scopus 로고
    • Characterization of an amsacrine-resistant line of human leukemic cells. Evidence for a drug-resistant form of topoisomerase II
    • [34] L.A. Zwelling, M. Hinds, D. Chan, J. Mayes, K.L. Sie, E. Parker, A. Silberman, A. Radcliffe, M. Beran, M. Blick, Characterization of an amsacrine-resistant line of human leukemic cells. Evidence for a drug-resistant form of topoisomerase II, J. Biol. Chem. 264 (1989) 16411-16420.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16411-16420
    • Zwelling, L.A.1    Hinds, M.2    Chan, D.3    Mayes, J.4    Sie, K.L.5    Parker, E.6    Silberman, A.7    Radcliffe, A.8    Beran, M.9    Blick, M.10
  • 35
    • 0013491598 scopus 로고
    • Decreased nuclear matrix DNA topoisomerase II (topo II) in VM-26 resistant human leukaemia cells
    • [35] D.J. Fernandes, M.K. Dansk, W.Y. Beck, Decreased nuclear matrix DNA topoisomerase II (topo II) in VM-26 resistant human leukaemia cells, Proc. Am. Assoc. Cancer Res. 30 (1989) 502.
    • (1989) Proc. Am. Assoc. Cancer Res. , vol.30 , pp. 502
    • Fernandes, D.J.1    Dansk, M.K.2    Beck, W.Y.3
  • 38
    • 0024318022 scopus 로고
    • Nonreproductive rearrangement of DNA topoisomerase I and II genes: Correlation with resistance to topoisomerase inhibitors
    • [38] K.B. Tan, M.R. Mattern, W.K. Eng, F.L. Eng, McCabe, R.K. Johnson, Nonreproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors, J. Natl. Cancer Inst. 81 (1989) 1732-1735.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 1732-1735
    • Tan, K.B.1    Mattern, M.R.2    Eng, W.K.3    Eng, F.L.4    McCabe5    Johnson, R.K.6
  • 40
    • 0022896243 scopus 로고
    • A specific marker for cell proliferation
    • [40] M.M. Heck, W.C. Earnshaw, A specific marker for cell proliferation, J. Cell Biol. 103 (1986) 2569-2581.
    • (1986) J. Cell Biol. , vol.103 , pp. 2569-2581
    • Heck, M.M.1    Earnshaw, W.C.2
  • 41
    • 0023927993 scopus 로고
    • Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells
    • [41] Y.H. Hsiang, H.Y. Wu, L.F. Liu, Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells, Cancer Res. 48 (1988) 3230-3235.
    • (1988) Cancer Res. , vol.48 , pp. 3230-3235
    • Hsiang, Y.H.1    Wu, H.Y.2    Liu, L.F.3
  • 43
    • 0023942412 scopus 로고
    • Increment of DNA topoisomerases in chemically and virally transformed cells
    • [43] M.D. Crespi, A.G. Mladovan, A. Baldi, Increment of DNA topoisomerases in chemically and virally transformed cells, Exp. Cell. Res. 175 (1988) 206-215.
    • (1988) Exp. Cell. Res. , vol.175 , pp. 206-215
    • Crespi, M.D.1    Mladovan, A.G.2    Baldi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.