pZ402, an improved SV40-based shuttle vector containing a T-antigen mutant unable to interact with wild-type p53

Gene

Volumn 211, Issue 2, 1998, Pages 229-234

  Kraus, Eliyahu ^a   Strong, Louise C ^a   Tainsky, Michael A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

DNA replication; Genomic instability

Indexed keywords

MUTANT PROTEIN; PROTEIN P53; T LYMPHOCYTE ANTIGEN;

ARTICLE; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; DNA TRANSFECTION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SHUTTLE VECTOR; SIMIAN VIRUS 40; TRANSCRIPTION INITIATION;

AMINO ACID SUBSTITUTION; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL LINE; CLONING, MOLECULAR; DNA REPLICATION; GENES, VIRAL; GENETIC VECTORS; HUMANS; POINT MUTATION; PROTEIN BINDING; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0032510722     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00121-8     Document Type: Article

References (33)

1. Amin N.S., Holm C. In vivo analysis reveals that the interdomain region of the yeast proliferating cell nuclear antigen is important for DNA replication and DNA repair. Genetics. 144:1996;479-493.
2. Bargonetti J., Friedman P.N., Kern S.E., Vogelstein B., Prives C. Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell. 65:1991;1083-1091.
3. Bischoff F.Z., Yim S.O., Pathak S., Grant G., Siciliano M.J., Giovanella B.C., Strong L.C., Tainsky M.A. Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization. Cancer Res. 50:1990;7979-7984.
4. Brush G.S., Kelly T.J., Stillman B. Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system. Meth. Enzymol. 262:1995;522-548.
5. Bushlop S., Gibson M.K., Wang X.W., Wagner P., Sturzbecher H.W., Harris C.C. Interaction of p53 with the human Rad 51 protein. Nucleic Acids Res. 25:1997;3868-3874.
6. Doerksen L.F., Bhattacharya A., Kannan P., Pratt D., Tainsky M.A. Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter. Nucleic Acids Res. 24:1996;2849-2856.
7. Drobetsky E.A., Grosovsky A.J., Glickman B.W. Perspectives on the use of an endogenous gene target in studies of mutational specificity. Mutat. Res. 220:1989;235-240.
8. Drobetsky E.A., Grosovsky A.J., Skandalis A., Glickman B.W. Perspectives on UV light mutagenesis: investigation of the CHO aprt gene carried on a retroviral shuttle vector. Somatic Cell Mol. Genet. 15:1989;401-409.
9. Dutta A., Ruppert J.M., Aster J.C., Winchester E. Inhibition of DNA replication factor RPA by p53 [see comments]. Nature. 365:1993;79-82.
10. El-deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell. 75:1993;817-825.
11. Harris C.C. p53: at the crossroads of molecular carcinogenesis and risk assessment. Science. 262:1993;1980-1981.
12. Hollstein M., Sidransky D., Vogelstein B., Harris C.C. p53 mutations in human cancers. Science. 253:1991;49-53.
13. Karasuyama H., Tohyama N., Tada T. Autocrine growth and tumorigenicity of interleuin 2 dependent helper T cells transfected with IL-2 gene. J. Exp. Med. 169:1989;13-25.
14. Kraemer K.H., Seidman M.M. Use of supF, an Escherichia coli tyrosine suppressor tRNA gene, as a mutagenic target in shuttle-vector plasmids. Mutat. Res. 220:1989;61-72.
15. Lee S.H., Kim D.K. The role of the 34-kDa subunit of human replication protein A in simian virus 40 DNA replication in vitro. J. Biol. Chem. 270:1995;12801-12807.
16. Li R., Botchan M.R. The acidic transcriptional activation domains of VP16 and p53 bind t he cellular replication protein A and stimulate in vitro BPV-1 DNA replication. Cell. 73:1993;1207-1221.
17. Lieter L.M., Chen J., Marathe T., Tanaka M., Dutta A. Loss of transactivation and transrepression function, and not RPA binding, alters growth suppression by p53. Oncogene. 12:1996;2661-2668.
18. Lin J., Simmons D.T. The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40. J. Virol. 65:1991;6447-6453.
19. Lin J., Simmons D.T. Stable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53. J. Virol. 64:1991;2066-2072.
20. Liu P.K., Kraus E., Wu T.A., Strong L.C., Tainsky M.A. Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations. Oncogene. 12:1996;2267-2278.
21. Malkin D., Li F.P., Strong L.C., Fraumeni J.F., Nelson C.E., Kim D.H., Kassel J., Gryka M.A., Bischoff F.Z., Tainsky M.A. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science. 250:1990;1233-1238.
22. Melendy T., Stillman B. An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication. J. Biol. Chem. 268:1993;3389-3395.
23. Morris G.F., Bischoff J.R., Mathews M.B. Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53. Proc. Natl. Acad. Sci. USA. 93:1996;895-899.
24. Sanchez Y., Elledge S.J. Stopped for repairs. Bioessays. 17:1995;545-548.
25. Seidman M.M., Dixon K., Razzaque A., Zagursky R.J., Berman M.L. A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells. Gene. 38:1985;233-237.
26. Shivakumar C.V., Brown D.R., Deb S., Deb S.P. Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter. Mol. Cell. Biol. 15:1995;6785-6793.
27. Shivji M.K., Grey S.J., Strausfeld U.P., Wood R.D., Blow J.J. Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair. Curr. Biol. 4:1994;1062-1068.
28. Smith M.L., Chen I.T., Zhan Q., Bae I., Chen C.Y., Gilmer T.M., Kastan M.B., PM O.C., Fornace A.J. Jr. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen [see comments]. Science. 266:1994;1376-1380.
29. Waga S., Bauer G., Stillman B. Reconstitution of complete SV40 DNA replication with purified replication factors. J. Biol. Chem. 269:1994;10923-10934.
30. Waga S., Hannon G.J., Beach D., Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA [see comments]. Nature. 369:1994;574-578.
31. Yin Y., Tainsky M.A., Bischoff F.Z., Strong L.C., Wahl G.M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell. 70:1992;937-948.
32. Yonish-Rouach E., Grunwald D., Wilder S., Kimchi A., May E., Lawrence J.J., May P., Oren M. p53-mediated cell death: relationship to cell cycle control. Mol. Cell. Biol. 13:1993;1415-1423.
33. Zhan Q., Carrier F., Fornace A.J. Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol. 13:1993;4242-4250.