Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine (PMEA)

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1402, Issue 1, 1998, Pages 29-38

  Balzarini, J ^a   Hatse, S ^a   Naesens, L ^a   De Clercq, E ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Cytostatic activity; PMEA; Resistance; Uptake

Indexed keywords

2,6 DIAMINO 9 (2 PHOSPHONOMETHOXYETHYL)PURINE; 9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)ADENINE; 9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)GUANINE; ACYCLIC NUCLEOSIDE; ADEFOVIR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CELL SELECTION; CELL SPECIFICITY; CONTROLLED STUDY; DRUG METABOLISM; DRUG RESISTANCE; LEUKEMIA L 1210; MUTANT; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; TECHNIQUE;

ADENINE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BIOTRANSFORMATION; CELL SURVIVAL; CYCLIC AMP; DRUG RESISTANCE, NEOPLASM; GUANINE; KINETICS; LEUKEMIA L1210; MICE; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; PURINE NUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE;

EID: 0032510432     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(97)00143-2     Document Type: Article

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