Design, synthesis, and evaluation of the multidrug resistance-reversing activity of D-glucose mimetics of hapalosin

Journal of Medicinal Chemistry

Volumn 41, Issue 6, 1998, Pages 981-987

  Dinh, Tam Q ^a,b   Smith, Charles D ^a   Du, Xiaohui ^b   Armstrong, Robert W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOPROTEIN P; HAPALOSIN; MULTIDRUG RESISTANCE PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; DRUG TRANSPORT; HUMAN; HUMAN CELL; MOLECULAR MODEL; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ATP-BINDING CASSETTE TRANSPORTERS; CELL SURVIVAL; DEPSIPEPTIDES; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GLUCOSE; HUMANS; LACTAMS; LACTONES; MOLECULAR MIMICRY; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; TUMOR CELLS, CULTURED;

EID: 0032510391     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970709p     Document Type: Article

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