Generation of allylic titanocene derivatives from vinyl halides and a Cp2TiCl2-Me3Al reagent system

Tetrahedron Letters

Volumn 39, Issue 7, 1998, Pages 583-586

  Hanzawa, Yuji ^a   Kowase, Noboru ^a   Taguchi, Takeo ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HALIDE; ORGANOMETALLIC COMPOUND; REAGENT; TITANOCENE; VINYL DERIVATIVE;

ARTICLE; SYNTHESIS;

EID: 0032509942     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10612-8     Document Type: Article

References (30)

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8. 3-allyltitanocene;
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16. 3Al (1 : 4) which was used without premixing failed to generate allylic titanocene.
17. 7. Reaction did not take place without using THF. Use of DMAP instead of THF did not give satisfactory results.
18. 13C), IR, MS and combusion analysis.
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20. 10. (equation presented)
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25. 2 reagent system depending on the reaction conditions in carbometalation reactions of acetylenes has also been reported. Negishi, E.; Kondakov, D. Y.; van Horn, D. E. Organometallics 1997, 16, 951. Thus, we cannot definitely rule out the possibility that another reaction mechanism leading to allylic titanocene 2 might take part in some extent in our cases.
26. 2 reagent system depending on the reaction conditions in carbometalation reactions of acetylenes has also been reported. Negishi, E.; Kondakov, D. Y.; van Horn, D. E. Organometallics 1997, 16, 951. Thus, we cannot definitely rule out the possibility that another reaction mechanism leading to allylic titanocene 2 might take part in some extent in our cases.
27. 2.
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30. 2) was isolated in a lower yield (20 %) through the reaction with aldehyde. We appreciate one of the referees for the kind suggestion to test about this reaction.