A carbohydrate approach to 4-hydroxy-2-cyclopentenone moiety of antitumor prostanoid punaglandin IV via alkylation of ester uronate

Tetrahedron Letters

Volumn 39, Issue 24, 1998, Pages 4247-4250

  Kuhn, Cyrille ^a,b   Florent, Jean Claude ^a  

^a INSTITUT CURIE   (France)

^b Research Institut of Jouveinal/Parke Davis   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PUNAGLANDIN IV; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHIRALITY; DRUG CONFORMATION; DRUG SYNTHESIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 0032508027     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00694-7     Document Type: Article

References (21)

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14. +.
15. 11. Prepared from 2,3-dichloroprop-1-ene (NaI, in acetone at reflux).
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19. +. Anal. Calcd. (%) C 62.83, H 6.72. Found (%) C 62.74, H 6.72.
20. 15. Kim, K.M.; Chung, K.H.; Kim, J.H.; Ryu, E. Synthesis 1993, 283-284.
21. 12, unit cell dimensions (Å) a = 9.602(7), b = 9.610(6), c = 7.3420(10).