-
1
-
-
0030250145
-
Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease
-
Barton A.J., Crook B.W., Karran E.H.et al. Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease. Neurodegeneration. 5:1996;213-218.
-
(1996)
Neurodegeneration
, vol.5
, pp. 213-218
-
-
Barton, A.J.1
Crook, B.W.2
Karran, E.H.3
-
2
-
-
0030638153
-
Developmental regulation of presenilin mRNA expression parallels notch expression
-
Berezovska O., Xia M.Q., Page K.et al. Developmental regulation of presenilin mRNA expression parallels notch expression. J Neuropathol Exp Neurol. 56:1997;40-44.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 40-44
-
-
Berezovska, O.1
Xia, M.Q.2
Page, K.3
-
3
-
-
0031006343
-
Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease
-
Busciglio J., Hartmann H., Lorenzo A.et al. Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease. J Neurosci. 17:1997;5101-5107.
-
(1997)
J Neurosci
, vol.17
, pp. 5101-5107
-
-
Busciglio, J.1
Hartmann, H.2
Lorenzo, A.3
-
4
-
-
0030581697
-
Molecular cloning, sequencing, and brain expression of the presenilin 1 gene in microcebus murinus
-
Calenda A., Mestrefrances N., Czech C.et al. Molecular cloning, sequencing, and brain expression of the presenilin 1 gene in microcebus murinus. Biochem Biophys Res Commun. 228:1996;430-439.
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 430-439
-
-
Calenda, A.1
Mestrefrances, N.2
Czech, C.3
-
5
-
-
0029982341
-
Widespread neuronal expression of the presenilin-1 early-onset Alzheimer's disease gene in the murine brain
-
Cribbs D.H., Chen L.S., Bende S.M.et al. Widespread neuronal expression of the presenilin-1 early-onset Alzheimer's disease gene in the murine brain. Am J Pathol. 148:1996;1797-1806.
-
(1996)
Am J Pathol
, vol.148
, pp. 1797-1806
-
-
Cribbs, D.H.1
Chen, L.S.2
Bende, S.M.3
-
6
-
-
0030293854
-
Protein topology of presenilin 1
-
Doan A., Thinakaran G., Borchelt D.R.et al. Protein topology of presenilin 1. Neuron. 17:1996;1023-1030.
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.R.3
-
7
-
-
10144234151
-
Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains
-
Elder G.A., Tezapsidis N., Carter J.et al. Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains. J Neurosci Res. 45:1996;308-320.
-
(1996)
J Neurosci Res
, vol.45
, pp. 308-320
-
-
Elder, G.A.1
Tezapsidis, N.2
Carter, J.3
-
8
-
-
0031017150
-
Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease
-
Giannakopoulos P., Bouras C., Kovari E.et al. Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease. Am J Pathol. 150:1997;429-436.
-
(1997)
Am J Pathol
, vol.150
, pp. 429-436
-
-
Giannakopoulos, P.1
Bouras, C.2
Kovari, E.3
-
9
-
-
15144345926
-
A novel presenilin 1 mutation: Increased beta-amyloid and neurofibrillary changes
-
Gomez-Isla T., Wasco W., Pettingell W.P.et al. A novel presenilin 1 mutation: Increased beta-amyloid and neurofibrillary changes. Ann Neurol. 41:1997;809-813.
-
(1997)
Ann Neurol
, vol.41
, pp. 809-813
-
-
Gomez-Isla, T.1
Wasco, W.2
Pettingell, W.P.3
-
10
-
-
0026501888
-
Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau
-
Greenberg S.G., Davies P., Scheim J.D.et al. Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. J Biol Chem. 267:1992;564-569.
-
(1992)
J Biol Chem
, vol.267
, pp. 564-569
-
-
Greenberg, S.G.1
Davies, P.2
Scheim, J.D.3
-
11
-
-
0029779589
-
Presenile because of presenilin: The presenilin genes and early onset Alzheimer's disease
-
Haass C. Presenile because of presenilin: the presenilin genes and early onset Alzheimer's disease. Curr Opin Neurol. 9:1996;254-259.
-
(1996)
Curr Opin Neurol
, vol.9
, pp. 254-259
-
-
Haass, C.1
-
12
-
-
0029805863
-
Characterization and expression of presenilin 1 in mouse brain
-
Huynh D.P., Ho V.V., Pulst S.M. Characterization and expression of presenilin 1 in mouse brain. Neuroreport. 7:1996;2423-2428.
-
(1996)
Neuroreport
, vol.7
, pp. 2423-2428
-
-
Huynh, D.P.1
Ho, V.V.2
Pulst, S.M.3
-
13
-
-
0026501562
-
Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease
-
Hyman B.T., Tanzi R.E., Marzloff B.A.et al. Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease. J Neuropathol Exp Neurol. 51:1992;76-83.
-
(1992)
J Neuropathol Exp Neurol
, vol.51
, pp. 76-83
-
-
Hyman, B.T.1
Tanzi, R.E.2
Marzloff, B.A.3
-
14
-
-
0030574051
-
Quantification of presenilin-1 mRNA in Alzheimer's disease brains
-
Johnston J.A., Froelich S., Lannfelt L.et al. Quantification of presenilin-1 mRNA in Alzheimer's disease brains. FEBS Lett. 394:1996;279-284.
-
(1996)
FEBS Lett
, vol.394
, pp. 279-284
-
-
Johnston, J.A.1
Froelich, S.2
Lannfelt, L.3
-
15
-
-
0022414054
-
Diagnosis of Alzheimer's disease
-
Khachaturian Z. Diagnosis of Alzheimer's disease. Arch Neurol. 52:1985;1097-1105.
-
(1985)
Arch Neurol
, vol.52
, pp. 1097-1105
-
-
Khachaturian, Z.1
-
16
-
-
0030868903
-
Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease
-
Kim T.-W., Pettingell W., Jung Y.-K.et al. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science. 277:1997;373-376.
-
(1997)
Science
, vol.277
, pp. 373-376
-
-
Kim, T.-W.1
Pettingell, W.2
Jung, Y.-K.3
-
17
-
-
0030890399
-
Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells
-
Kim T.W., Pettingell W.H., Hallmark O.G.et al. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells. J Biol Chem. 272:1997;11006-11010.
-
(1997)
J Biol Chem
, vol.272
, pp. 11006-11010
-
-
Kim, T.W.1
Pettingell, W.H.2
Hallmark, O.G.3
-
18
-
-
0028276801
-
Evidence that production and release of amyloid beta- protein involves the endocytic pathway
-
Koo E.H., Squazzo S.L. Evidence that production and release of amyloid beta- protein involves the endocytic pathway. J Biol Chem. 269:1994;17386-17389.
-
(1994)
J Biol Chem
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
19
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
Kovacs D.M., Fausett H.J., Page K.J.et al. Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med. 2:1996;224-229.
-
(1996)
Nature Med
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
-
20
-
-
0031017795
-
Light and electron microscopic localization of presenilin-1 in primate brain
-
Lah J.J., Heilman C.J., Nash N.R.et al. Light and electron microscopic localization of presenilin-1 in primate brain. J Neurosci. 17:1997;1971-1980.
-
(1997)
J Neurosci
, vol.17
, pp. 1971-1980
-
-
Lah, J.J.1
Heilman, C.J.2
Nash, N.R.3
-
21
-
-
0003448569
-
-
Cold Spring Harbor Laboratory Press, New York Ch. 13
-
Lane E, Harlow D. Antibodies, a laboratory manual, Cold Spring Harbor Laboratory Press, New York, 1988, Ch. 13.
-
(1988)
Antibodies, a Laboratory Manual
-
-
Lane, E.1
Harlow, D.2
-
22
-
-
10544229795
-
Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues
-
Lee M.K., Slunt H.H., Martin L.J.et al. Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. J Neurosci. 16:1996;7513-7525.
-
(1996)
J Neurosci
, vol.16
, pp. 7513-7525
-
-
Lee, M.K.1
Slunt, H.H.2
Martin, L.J.3
-
23
-
-
0030922146
-
Evidence for a six-transmembrane domain structure of presenilin 1
-
Lehmann S., Chiesa R., Harris D.A. Evidence for a six-transmembrane domain structure of presenilin 1. J Biol Chem. 272:1997;12047-12051.
-
(1997)
J Biol Chem
, vol.272
, pp. 12047-12051
-
-
Lehmann, S.1
Chiesa, R.2
Harris, D.A.3
-
24
-
-
16044365171
-
The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology
-
Lemere C.A., Lopera F., Kosik K.S.et al. The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology. Nature Med. 2:1996;1146-1150.
-
(1996)
Nature Med
, vol.2
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
-
25
-
-
15444350008
-
Presenilin-1 protein expression in familial and sporadic Alzheimer's disease
-
Levey A.I., Heilman C.J., Lah J.J.et al. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease. Ann Neurol. 41:1997;742-753.
-
(1997)
Ann Neurol
, vol.41
, pp. 742-753
-
-
Levey, A.I.1
Heilman, C.J.2
Lah, J.J.3
-
26
-
-
0030761059
-
Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation
-
Li J., Xu M., Zhou H.et al. Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation. Cell. 90:1997;917-927.
-
(1997)
Cell
, vol.90
, pp. 917-927
-
-
Li, J.1
Xu, M.2
Zhou, H.3
-
27
-
-
0029984314
-
Immunohistochemical analysis of presenilin-1 expression in the mouse brain
-
Moussaoui S., Czech C., Pradier L.et al. Immunohistochemical analysis of presenilin-1 expression in the mouse brain. FEBS Lett. 383:1996;219-222.
-
(1996)
FEBS Lett
, vol.383
, pp. 219-222
-
-
Moussaoui, S.1
Czech, C.2
Pradier, L.3
-
28
-
-
10544239098
-
Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease
-
Murphy G.M. Jr., Forno L.S., Ellis W.G.et al. Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease. Am J Pathol. 149:1996;1839-1846.
-
(1996)
Am J Pathol
, vol.149
, pp. 1839-1846
-
-
Murphy G.M., Jr.1
Forno, L.S.2
Ellis, W.G.3
-
29
-
-
0030246887
-
Presenilin 1 mRNA expression in hippocampi of sporadic Alzheimer's disease patients
-
Nishiyama K., Murayama S., Suzuki T.et al. Presenilin 1 mRNA expression in hippocampi of sporadic Alzheimer's disease patients. Neurosci Res. 26:1996;75-78.
-
(1996)
Neurosci Res
, vol.26
, pp. 75-78
-
-
Nishiyama, K.1
Murayama, S.2
Suzuki, T.3
-
30
-
-
0030459831
-
In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain
-
Page K., Hollister R., Tanzi R.E.et al. In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain. Proc Natl Acad Sci USA. 93:1996;14020-14024.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14020-14024
-
-
Page, K.1
Hollister, R.2
Tanzi, R.E.3
-
31
-
-
0030889220
-
Presenilin proteins undergo heterogeneous endoproteolysis between Thr(291) and Ala(299) and occur as stable N- And C-terminal fragments in normal and Alzheimer brain tissue
-
Podlisny M.B., Citron M., Amarante P.et al. Presenilin proteins undergo heterogeneous endoproteolysis between Thr(291) and Ala(299) and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue. Neurobiol Dis. 3:1997;325-337.
-
(1997)
Neurobiol Dis
, vol.3
, pp. 325-337
-
-
Podlisny, M.B.1
Citron, M.2
Amarante, P.3
-
32
-
-
0029802404
-
Localization of presenilin-1 mRNA in rat brain
-
Quarteronet D., Pradier L., Czech C.et al. Localization of presenilin-1 mRNA in rat brain. Neuroreport. 7:1996;2587-2591.
-
(1996)
Neuroreport
, vol.7
, pp. 2587-2591
-
-
Quarteronet, D.1
Pradier, L.2
Czech, C.3
-
33
-
-
0030048505
-
Identification and characterization of presenilin I-467, I-463 and I-374
-
Sahara N., Yahagi Y., Takagi H.et al. Identification and characterization of presenilin I-467, I-463 and I-374. FEBS Lett. 381:1996;7-11.
-
(1996)
FEBS Lett
, vol.381
, pp. 7-11
-
-
Sahara, N.1
Yahagi, Y.2
Takagi, H.3
-
34
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R., Rogaev E.I., Liang Y.et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
35
-
-
0029670218
-
Regional and cellular presenilin 1 gene expression in human and rat tissues
-
Suzuki T., Nishiyama K., Murayama S.et al. Regional and cellular presenilin 1 gene expression in human and rat tissues. Biochem Biophys Res Commun. 219:1996;708-713.
-
(1996)
Biochem Biophys Res Commun
, vol.219
, pp. 708-713
-
-
Suzuki, T.1
Nishiyama, K.2
Murayama, S.3
-
36
-
-
0031044834
-
Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains
-
Takami K., Terai K., Matsuo A.et al. Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains. Brain Res. 748:1997;122-130.
-
(1997)
Brain Res
, vol.748
, pp. 122-130
-
-
Takami, K.1
Terai, K.2
Matsuo, A.3
-
37
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
Thinakaran G., Borchelt D.R., Lee M.K.et al. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron. 17:1996;181-190.
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
-
38
-
-
0029843172
-
Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: Double-labeling immunohistochemical study
-
Uchihara T., el Hachimi H.K., Duyckaerts C.et al. Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labeling immunohistochemical study. Acta Neuropathol. 92:1996;325-330.
-
(1996)
Acta Neuropathol
, vol.92
, pp. 325-330
-
-
Uchihara, T.1
El Hachimi, H.K.2
Duyckaerts, C.3
-
39
-
-
8044231311
-
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum
-
Walter J., Capell A., Grunberg J.et al. The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum. Mol Med. 2:1996;673-691.
-
(1996)
Mol Med
, vol.2
, pp. 673-691
-
-
Walter, J.1
Capell, A.2
Grunberg, J.3
-
40
-
-
0031024228
-
Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques
-
Weber L.L., Leissring M.A., Yang A.J.et al. Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques. Exp Neurol. 143:1997;37-44.
-
(1997)
Exp Neurol
, vol.143
, pp. 37-44
-
-
Weber, L.L.1
Leissring, M.A.2
Yang, A.J.3
-
41
-
-
0028822488
-
S182 protein in Alzheimer's disease neuritic plaques
-
Wisniewski T., Palha J.A., Ghiso J.et al. S182 protein in Alzheimer's disease neuritic plaques. Lancet. 346:1995;1366.
-
(1995)
Lancet
, vol.346
, pp. 1366
-
-
Wisniewski, T.1
Palha, J.A.2
Ghiso, J.3
-
42
-
-
0030951449
-
Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease
-
Xia M.Q., Qin S.X., McNamara M.et al. Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease. Am J Pathol. 150:1997;1267-1274.
-
(1997)
Am J Pathol
, vol.150
, pp. 1267-1274
-
-
Xia, M.Q.1
Qin, S.X.2
McNamara, M.3
-
43
-
-
16944365745
-
Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins
-
Xia W., Zhang J., Kholodenko D.et al. Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins. J Biol Chem. 272:1997;7977-7982.
-
(1997)
J Biol Chem
, vol.272
, pp. 7977-7982
-
-
Xia, W.1
Zhang, J.2
Kholodenko, D.3
|