Transglutaminase activity in serum and cerebrospinal fluid in sporadic amyotrophic lateral sclerosis: A possible use as an indicator of extent of the motor neuron loss

Journal of the Neurological Sciences

Volumn 158, Issue 1, 1998, Pages 53-57

  Fujita, Kimikazu ^a   Honda, Masao ^b   Hayashi, Ryuichiro ^b   Ogawa, Kazuhito ^a   Ando, Masato ^c   Yamauchi, Masamitsu ^a   Nagata, Yutaka ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c AICHI GAKUSEN UNIVERSITY   (Japan)

Author keywords

Cerebrospinal fluid (CSF); Serum; Sporadic amyotrophic lateral sclerosis (SALS); Transglutaminase (TGase)

Indexed keywords

PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOTOR NEURON DISEASE; PRIORITY JOURNAL; SPINAL CORD TRANSSECTION;

AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; BIOLOGICAL MARKERS; CELL DEATH; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR NEURONS; NERVE TISSUE PROTEINS; SPINAL CORD; TRANSGLUTAMINASES;

EID: 0032507891     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(98)00088-4     Document Type: Article

References (20)

1. Ando M., Kunii S., Tatematsu T., Nagata Y. Selective alterations in transglutaminase activity in rat superior cervical ganglia in response to neurotransmitters, high potassium and sialic acid-containing compounds. Brain Res. 604:1993;64-68.
2. Bradford M.M. A rapid and sensitive method for the quantitation of mocrogram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-252.
3. Burt D.R. Muscarinic receptor binding in rat sympathetic ganglia is unaffected by degeneration. Brain Res. 143:1978;573-579.
4. Caroscio J.T., Mulvihill M.M., Sterling R., Abrams B. Amyotrophic lateral sclerosis: its natural history. Neurol. Clin. 5:1987;91-101.
5. Fesus L., Thomazy V., Falus A. Induction and activation of tissue transglutaminases during programmed cell death. FEBS Lett. 224:1987;104-108.
6. Fesus L., Thomazy V., Falus A. Searching of tissue transglutaminase; its possible involvement in biochemical pathway of programmed cell death. Adv. Exp. Biol. 231:1988;119-134.
7. Fujita K., Ando M., Yamauchi M., Nagata Y., Honda M. Alteration of transglutaminase activity in rat and human spinal cord after neuronal degeneration. Neurochem. Res. 20:1995;1195-1201.
8. Fujita K., Shibayama K., Yamauchi M., Kato M., Takahashi H., Iritani K., Yoshimoto N., Nagata Y. Alteration of enzymic activities implicating in neuronal degeneration in the spinal cord of motor neuron degeneration mouse during postnatal development. Neurochem. Res. 23:1998;561-566.
9. Folk J.E. Transglutaminase. Annu. Rev. Biochem. 49:1980;527-531.
10. Folk J.E., Park M.H., Chung S.L., Lester E.P., Cooper H.L. Polyamines as physiological substrates for transglutaminase. J. Biol. Chem. 255:1980;3693-3700.
11. Gilad G.M., Varon L.F., Gilad V.H. Calcium-dependent transglutaminase of rat sympathetic ganglia in development and after nerve injury. J. Neurochem. 44:1985;1385-1390.
12. Honda M. Clinical appraisal of progression of amyotrophic lateral sclerosis; a Japanese ALS scale, in amyotrophic lateral sclerosis. In: Rose FC, editor. Amyotrophic Lateral Sclerosis, New York: Demos Publ 1990:77-82.
13. Kawashima S., Ihara Y., Inomata M. Transglutaminase and calcium protease activities in Alzheimer's disease brain. Biomed. Res. 10:1989;17-23.
14. Lorand L., Campbell-Wilkes L.M., Cooperstein L.A. Filter paper assay for transamidating enzyme using radioactive amine substrate. Anal. Biochem. 72:1972;17-23.
15. Lorand L., Losowsky M.S., Miloszewski K.J.M. Human factor X III; fibrin stabilizing factor. Prog. Haemost. Thrombos. 5:1980;241-289.
16. Messer A., Strominger N.L., Mazurkiewicz J.E. Histopathology of the late-onset motor degeneration (Mnd) mutant in the mouse. Neurogenet. 4:1987;201-213.
17. Nagata Y., Tsukada Y. Effect of degeneration of sympathtic ganglion cells on amino acid metabolism in cervical ganglion from the rat. Exp. Brain. Res. 5:1986;202-209.
18. Rosengren L.E., Karlsson J.E., Larson J.O., Persson L.I., Wikkels C. Patients with amyotrophic lateral sclerosis and other neurodegenerative disease have increase levels of neurofilament protein in CSF. J. Neurochem. 67:1996;2013-2018.
19. Rosengren L.E., Lyke J., Andersen O. Glial fibrillary acidic protein (GFAP) was increase in CSF of multiple sclerosis and the levels correlate with the neurological deficit. J. Neurol. Sci. 133:1995;61-65.
20. Sakata Y., Aoki N. Significance of cross-linking 2-plasmin inhibitor to fibrin in inhibition of fibrinolysis and hemostasis. J. Clin. Invest. 69:1980;290-297.