Advances in periodontal diagnosis 7. Proteolytic and hydrolytic enzymes link with periodontitis

British Dental Journal

Volumn 184, Issue 7, 1998, Pages 323-328

  Eley, B M ^a   Cox, S W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ARYLSULFATASE; ASPARTIC PROTEINASE; BETA GLUCURONIDASE; BIOLOGICAL MARKER; COLLAGENASE; CYSTEINE PROTEINASE; HYDROLASE; LACTOFERRIN; LYSOZYME; PEPTIDE HYDROLASE; PEROXIDASE; SERINE PROTEINASE;

ENZYMOLOGY; HUMAN; PERIODONTAL DISEASE; PERIODONTITIS; REVIEW;

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ARYLSULFATASES; ASPARTIC ENDOPEPTIDASES; BIOLOGICAL MARKERS; COLLAGENASES; CYSTEINE ENDOPEPTIDASES; GLUCURONIDASE; HUMANS; HYDROLASES; LACTOFERRIN; MURAMIDASE; PEPTIDE HYDROLASES; PERIODONTAL DISEASES; PERIODONTITIS; PEROXIDASE; SERINE ENDOPEPTIDASES;

EID: 0032507332     PISSN: 00070610     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bdj.4809617     Document Type: Article

References (47)

1. Kowashi Y, Jaccard F, Cimasoni G. Increase of free collagenase and neutral protease activities in the gingival crevice during experimental gingivitis in Man. Archs Oral Biol 1979; 34: 645-650.
2. Overall C M, Sodek J. Initial characterisation of a neutral metalloproteinase, active on 3/4-collagen fragments, synthesised by ROS 17/2.8 osteoblastic cells, periodontal fibroblasts, and identified in gingival crevicular fluid. J Dent Res 1987; 66: 1271-1282.
3. Kryshalskyi E, Sodek J, Ferner J M. Correlation of collagenolytic enzymes and inhibitors in gingival crevicular fluid with clinical and microscopic changes in experimental periodontitis in the dog. Archs Oral Biol 1986; 31: 21-31.
4. Kryshalskyi E, Sodek J. Nature of collagenolytic enzyme and inhibitor activity in gingival crevicular fluid from healthy and inflamed periodonta! tissues of beagle dogs. J Periodont Res 1987; 22: 264-269.
5. Villela B, Cogan R B, Bartolucci A A, Birkedal-Hansen H. Collagenolytic activity in crevicular fluid from patients with chronic adult periodontitis, localised juvenile periodontitis and gingivitis, and from healthy control subjects. J Periodont Res 1987; 22: 381-389.
6. Larivee L, Sodek J, Ferrier J M. Collagenase and collagenase inhibitor activity in crevicular fluid of patients receiving treatment for localised juvenile periodontitis. J Periodont Res 1986; 21: 702-715.
7. Golub L M, Siegel K, Ramamurthy N S, Mandel ID. Some characteristics of collagenase activity in gingival crevicular fluid and its relationship to gingival disease in humans. J Dent Res 1976; 55: 1049-1057.
8. Hakkarainen K, Uitto V-I, Ainamo J. Collagenase activity and protein content of sulcular fluid after scaling and occlusal adjustment of teeth with deep periodontal pockets. J Periodont Res 1988; 23: 204-21 0
9. Lee W, Aitken S, Sodek J, McCullock C A G. Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: role of active enzyme in human periodontitis. J Periodont Res 1995; 30: 23-33.
10. Vaes G. Cellular biology and biochemical mechanism of bone resorption. Clin Orthopaed Rel Res 1988; 231: 239-271.
11. Eley B M, Cox S W. Cathepsin B and L-like activities at local gingival sites of chronic periodontitis patients. J Clin Periodontol 1991; 18: 499-504.
12. Cox S W, Eley B M. The detection of cathepsin B- and L-, elastase-, tryptase-, trypsin- and dipeptidyl peptidase IV- like activities in gingival crevicular fluid from gingivitis and periodontitis patients using peptidyl derivatives of 7-amino-4-trifluomethylcoumarin. J Periodont Res 1989; 24: 353-361.
13. Eley B M, Cox S W. Cathepsin B/L-, elastase-, tryptase-, trypsin- and dipeptidyl peptidase IV-like activities in gingival crevicular fluid: correlation with clinical parameters in untreated chronic periodontitis patients. J Periodont Res 1992; 27: 62-69.
14. Eley B M, Cox S W. Correlation of gingival crevicular fluid proteases with clinical and radiological parameters of periodontal attachment loss. J Dent 1992c; 20: 90-99.
15. Cox S W, Eley B M. Cathepsin B/L-, elastase-, tryptase-, trypsin- and dipeptidyl peptidase IV-like activities in gingival crevicular fluid: a comparison of levels before and after basic periodontal treatment of chronic periodontitis patients. J Clin Periodontol 1992; 19: 333-339.
16. Eley B M, Cox S W. Cathepsin B/L-, elastase-, tryptase-, trypsin- and dipeptidyl peptidase IV-like activities in gingival crevicular fluid: a comparison of levels before and after periodontal surgery in chronic periodontitis patients. J Periodontol 1992; 63: 412-417.
17. Eley B M, Cox S W. Gingival crevicular fluid inflammatory cell proteases at healthy, gingivitis and periodontitis sites. J Dent Res 1993; 72: 705.
18. Eley B M, Cox S W. The relationship between gingival crevicular fluid cathepsin B activity and periodontal attachment loss in chronic periodontitis patients. A 2-year longitudinal study. J Periodontol Res 1996; 31: 381-392.
19. Cox S W, Cho K, Eley B M, Smith R E. A simple, combined fiuorogenic and chromogenic method for the assay of proteases in gingival crevicular fluid. J Periodont Res 1990; 25: 164-171.
20. Ishiwaka I, Cimasoni G, Ahmad-Zadeh C. Possible role of lysosomal enzymes in the pathogenesis of periodontitis. A study of cathepsin D in human gingival fluid. Archs Oral Biol 1972; 17: 111-117.
21. Eley B M, Cox S W. A biochemical study of serine proteinase activities at local gingivitis sites in human chronic periodontitis. Archs Oral Biol 1990; 35: 23-27.
22. Palcanis K G, Larjava IK, Wells B R et al. Elastase as an indicator of periodontal disease progression. J Periodontol 1992; 63: 237-274.
23. Eley B M, Cox S W. A 2-year longitudinal study of elastase in gingival crevicular fluid and periodontal attachment loss. J Clin Periodontol 1996; 23: 681-692.
24. Cox S W, Eley B M. Identification of a tryptase-like enzyme in extracts of inflamed human gingiva by effector and gel-filtration studies. Archs Oral Biol 1989; 34: 219-221.
25. Cox S W, Eley B M. Tryptase-like activity in crevicular fluid from gingivitis and periodontitis patients. J Periodont Res 1989; 24: 41-44.
26. Jeffcoat M K, Williams R C, Johnson H G, Wechter W J, Goldhaber B. Treatment of periodontal disease in beagles with lodoxamide ethyl, an inhibitor of mast cell release. J Periodont Res 1985; 20: 532-541.
27. Kennett C N, Cox S W, Eley B M. Histochemical, immunocytochemical and biochemical studies of dipeptidyl peptidases in human gingival tissue. J Dent Res 1995; 74: 845.
28. Cox S W, Gazi M I, Eley B M. Dipeptidyl peptidase II- and IV- like activities in gingival tissue and crevicular fluid from human periodontitis lesions. Archs Oral Biol 1992; 37: 167-173.
29. Kennen C N, Cox S W, Eley B M. The histochemical and immunocytochemical localisation of dipeptidylpeptidase II and IV in human gingiva. J Periodontol 1996; 67: 846-852.
30. Kennett C N, Cox S W, Eley B M. Unpublished observations.
31. Eley B M, Cox S W. Bacterial proteases in gingival crevicuiar fluid before and after periodontal treatment. Br Dent J 1995; 178: 133-139.
32. Eley B M, Cox S W. Crevicular fluid dipeptidyl peptidase activities before and after periodontal treatment. J Dent Res 1992; 71: 622.
33. Eley B M, Cox S W. Correlation between gingival crevicular fluid dipeptidyl peptidase II and IV activity and periodontal attachment loss. A 2-year longitudinal study in chronic periodontilis patients. Oral Dis 1995; 1: 201-213.
34. Lamster I B. The host response in gingival crevicular fluid: potential applications in periodontitis clinical trials. J Periodontol 1992; 63: 1117-1123.
35. Page RC. Host response tests for diagnosing periodontal diseases. J Periodontol 1992; 63: 356-366.
36. Lamster IB, Oshrain R L, Harper D S, Celenti R S, Hovilaras C A, Gordon J M. Enzyme activity in crevicular fluid for detection and prediction of clinical attachment loss in patients with chronic adult periodontitis. J Periodontol 1988; 59: 516-523.
37. Lamster IB, Oshrain R L, Celenti R S, Fine J B, Grbic J T. Indicators of the acute inflammatory and humoral immune responses in gingival crevicular fluid: Relationship to active periodontal disease. J Periodont Res 1991; 26: 261-263.
38. Lamster IB, Holmes L G, Gross K B W et al. (1994) The relationship of β-glucuronidase activity in crevicular fluid to clinical parameters of periodontal disease. Findings from a multicentre study. J Clin Periodontol 1994; 21; 118-127.
39. Ishiwaka I, Cimasoni G. Alkaline phosphatase in human gingival fluid and its relationship to periodontitis. Archs Oral Biol 1970; 15: 1401-1404.
40. Binder T A, Goodson J M, Socransky S S. Gingival fluid levels of acid and alkaline phosphatase levels. J Periodont Res 1987; 22: 14-19.
41. Smith Q T, Hinrichs J E, Melnyk R S. Gingival crevicular fluid myeloperoxidase at periodontitis sites. J Periodont Res 1986; 21: 45-55.
42. Cao C F, Smith Q T. Crevicular fluid myeloperoxidase at healthy, gingivitis and periodontitis sites. J Clin Periodontol 1989; 16: 17-20.
43. Friedman S A, Mandel I D, Herrera M S. Lysozyme and lactoferrin quantifications in crevicular fluid. J Periodontol 1983; 54: 347-350.
44. Kennett C N, Cox S W, Eley B M. Comparative histochemical, biochemical and immunocytochemical studies of cathepsin B in human gingiva. J Periodont Res 1994; 29: 870-877.
45. Kennett C N, Cox S W, Eley B M. Localisation of active and inactive elastase, alpha-1-proteinase inhibitor and alpha-2-macroglobulin in human gingiva. J Dent Res 1995; 74: 667-674.
46. Kennett C N, Cox S W, Eley B M, Osman I A R M. Comparative histochemical and biochemical studies of mast cell tryptase in human gingiva. J Periodontol 1993; 64: 870-877.
47. Kennett C N, Cox S W, Eley B M. Investigations into the cellular contribution of host tissue protease actvity in gingival crevicular fluid. J Clin Periodontol 1997; 24: 424-431.