Agonist-mediated downregulation of G(αi) via the α2-adrenergic receptor is targeted by receptor-G(i) interaction and is independent of receptor signaling and regulation

Biochemistry

Volumn 37, Issue 45, 1998, Pages 15720-15725

  Jewell Motz, Elizabeth A ^a   Donnelly, Elizabeth T ^a   Eason, Margaret G ^a   Liggett, Stephen B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ADRENERGIC RECEPTOR; CYCLIC AMP; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; PROTEIN G;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL; DOWN REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SECOND MESSENGER; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; CHO CELLS; CRICETINAE; DOWN-REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, ALPHA-2; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

ANIMALIA;

EID: 0032506047     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980999r     Document Type: Article

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