Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution

Biochemistry

Volumn 37, Issue 45, 1998, Pages 15896-15907

  Krzywda, Szymon ^a,b   Murshudov, Garib N ^a,c   Brzozowski, Andrzej M ^a   Jaskolski, Mariusz ^b   Scott, Emily E ^d   Klizas, Sarah A ^d   Gibson, Quentin H ^d   Olson, John S ^d   Wilkinson, Anthony J ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

^c DARESBURY LABORATORY   (United Kingdom)

^d RICE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; MYOGLOBIN; VALINE; CARBON MONOXIDE; DEOXYMYOGLOBIN; DRUG DERIVATIVE; NITRIC OXIDE; OXYGEN;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; GENETIC RECOMBINATION; HYDROGEN BOND; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; STRUCTURE ANALYSIS; ANIMAL; BINDING SITE; CHEMISTRY; CRYSTALLIZATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SITE DIRECTED MUTAGENESIS; SWINE; WHALE; X RAY CRYSTALLOGRAPHY;

CETACEA; OXY; PHYSETER CATODON;

AMINO ACID SUBSTITUTION; ANIMALS; ASPARAGINE; BINDING SITES; CARBON MONOXIDE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; MYOGLOBIN; NITRIC OXIDE; OXYGEN; SWINE; VALINE; WHALES;

EID: 0032505873     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9812470     Document Type: Article

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