메뉴 건너뛰기




Volumn 14, Issue 10, 1998, Pages 825-833

Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP- dependent protein kinaes pathways

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INTERLEUKIN 6; MESSENGER RNA; PROTEIN KINASE C; TRANSACTIVATOR PROTEIN;

EID: 0032504015     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1998.14.825     Document Type: Article
Times cited : (77)

References (68)
  • 3
    • 0027257418 scopus 로고
    • Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood-brain barrier
    • Power C, Kong P-A, Crawford TO, Wesselingh S, Glass JD, McArthur JC, and Trapp BD: Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood-brain barrier. Ann Neurol 1993;34:339-350.
    • (1993) Ann Neurol , vol.34 , pp. 339-350
    • Power, C.1    Kong, P.-A.2    Crawford, T.O.3    Wesselingh, S.4    Glass, J.D.5    McArthur, J.C.6    Trapp, B.D.7
  • 4
    • 0023224755 scopus 로고
    • Neuropathology of acquired immune deficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinuclear giant cells
    • Kato T, Hirano A, Llena J, and Dembitzer H: Neuropathology of acquired immune deficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinuclear giant cells. Acta Neuropathol 1987;73:287-294.
    • (1987) Acta Neuropathol , vol.73 , pp. 287-294
    • Kato, T.1    Hirano, A.2    Llena, J.3    Dembitzer, H.4
  • 5
    • 0025787561 scopus 로고
    • HIV-1 infection of the nervous system: An autopsy study of 268 adult, pediatric, and fetal brains
    • Kure K, Llena JF, Lyman WD, Soeiro R, Weidenheim KM, Hirano A, and Dickson D: HIV-1 infection of the nervous system: An autopsy study of 268 adult, pediatric, and fetal brains. Hum Pathol 1990;22:700-710.
    • (1990) Hum Pathol , vol.22 , pp. 700-710
    • Kure, K.1    Llena, J.F.2    Lyman, W.D.3    Soeiro, R.4    Weidenheim, K.M.5    Hirano, A.6    Dickson, D.7
  • 6
    • 0023225928 scopus 로고
    • HIV antigen in the brain of patients with AIDS dementia complex
    • Pumarola-Sune T, Navia B, and Cordon-Cardo C: HIV antigen in the brain of patients with AIDS dementia complex. Ann Neurol 1987;21:490-496.
    • (1987) Ann Neurol , vol.21 , pp. 490-496
    • Pumarola-Sune, T.1    Navia, B.2    Cordon-Cardo, C.3
  • 7
    • 0026134425 scopus 로고
    • Immunopathogenesis of HIV encephalitis
    • Achim C, Schrier R, and Wiley C: Immunopathogenesis of HIV encephalitis. Brain Pathol 1991;1:177-184.
    • (1991) Brain Pathol , vol.1 , pp. 177-184
    • Achim, C.1    Schrier, R.2    Wiley, C.3
  • 8
    • 0023852121 scopus 로고
    • The human immunodeficiency virus type I: Infectivity and mechanism of pathogenesis
    • Fauci AS: The human immunodeficiency virus type I: Infectivity and mechanism of pathogenesis. Science 1988;239:617-622.
    • (1988) Science , vol.239 , pp. 617-622
    • Fauci, A.S.1
  • 9
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphocyte virus type III (HTLV-III)
    • Arya SK, Guo C, Josephs SF, and Wong-Staal F: Trans-activator gene of human T-lymphocyte virus type III (HTLV-III). Science 1985;229:69-73.
    • (1985) Science , vol.229 , pp. 69-73
    • Arya, S.K.1    Guo, C.2    Josephs, S.F.3    Wong-Staal, F.4
  • 10
    • 0022500166 scopus 로고
    • The trans-activator gene of the human T cell lymphotropic virus type III is required for replication
    • Dayton AI, Sodroski JG, Rosen CA, Goh WC, and Haseltine WA: The trans-activator gene of the human T cell lymphotropic virus type III is required for replication. Cell 1986;44:941-947.
    • (1986) Cell , vol.44 , pp. 941-947
    • Dayton, A.I.1    Sodroski, J.G.2    Rosen, C.A.3    Goh, W.C.4    Haseltine, W.A.5
  • 11
    • 0023037537 scopus 로고
    • Expression and characterization of the trans-activator of HTLV-III/LAV virus
    • Wright CM, Felber BK, Paskalis H, and Pavlakis GN: Expression and characterization of the trans-activator of HTLV-III/LAV virus. Science 1986;234:988-992.
    • (1986) Science , vol.234 , pp. 988-992
    • Wright, C.M.1    Felber, B.K.2    Paskalis, H.3    Pavlakis, G.N.4
  • 12
    • 0026513502 scopus 로고
    • Human immunodeficiency virus (HIV) Tat-reactive antibodies present in normal HIV-negative sera and depleted in HIV-positive sera. Identification of the epitope
    • Rodman TC, Pruslin FH, To SE, and Winston R: Human immunodeficiency virus (HIV) Tat-reactive antibodies present in normal HIV-negative sera and depleted in HIV-positive sera. Identification of the epitope. J Exp Med 1992;175:1247-1253.
    • (1992) J Exp Med , vol.175 , pp. 1247-1253
    • Rodman, T.C.1    Pruslin, F.H.2    To, S.E.3    Winston, R.4
  • 13
    • 0024262589 scopus 로고
    • Cellular uptake of the Tat protein from human immunodeficiency virus
    • Frankel AD and Pabo CO: Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 1988;55:1189-1193.
    • (1988) Cell , vol.55 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 14
    • 0025344596 scopus 로고
    • Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients
    • Ensoli B, Barillari G, Salahuddin CZ, Gallo RC, and Wong-Staal F: Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature (London) 1990;345:84-86.
    • (1990) Nature (London) , vol.345 , pp. 84-86
    • Ensoli, B.1    Barillari, G.2    Salahuddin, C.Z.3    Gallo, R.C.4    Wong-Staal, F.5
  • 15
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 tat protein on cell growth and viral transactivation
    • Ensoli B, Buonagoro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, and Gallo RC: Release, uptake, and effects of extracellular human immunodeficiency virus type 1 tat protein on cell growth and viral transactivation. J Virol 1993;67:277-287.
    • (1993) J Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonagoro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 16
    • 0025797055 scopus 로고
    • Endocytosis and targeting of exogenous HIV-1 Tat protein
    • Mann DA and Frankel AD: Endocytosis and targeting of exogenous HIV-1 Tat protein. EMBO J 1991;10:1733-1739.
    • (1991) EMBO J , vol.10 , pp. 1733-1739
    • Mann, D.A.1    Frankel, A.D.2
  • 17
    • 0025162671 scopus 로고
    • Identification of an Arg-Gly-Asp (RGD) cell adhesion site in human immunodeficiency type 1 transactivation protein, Tat
    • Brake DA, DeBouck C, and Biesecker G: Identification of an Arg-Gly-Asp (RGD) cell adhesion site in human immunodeficiency type 1 transactivation protein, Tat. J Cell Biol 1988;111:1275-1281.
    • (1988) J Cell Biol , vol.111 , pp. 1275-1281
    • Brake, D.A.1    DeBouck, C.2    Biesecker, G.3
  • 18
    • 0027220944 scopus 로고
    • The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence
    • Barillari G, Gendelman R, Gallo RC, and Ensoli B: The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc Natl Acad Sci USA 1993;90:7941-7945.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7941-7945
    • Barillari, G.1    Gendelman, R.2    Gallo, R.C.3    Ensoli, B.4
  • 23
    • 0027198219 scopus 로고
    • Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells
    • Flores SC, Marecki JC, Harper KP, Bose SK, Nelson SK, and McCord JM: Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells. Proc Natl Acad Sci USA 1993;90:7632-7636.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7632-7636
    • Flores, S.C.1    Marecki, J.C.2    Harper, K.P.3    Bose, S.K.4    Nelson, S.K.5    McCord, J.M.6
  • 24
    • 0027050012 scopus 로고
    • Down-modulation of cell surface expression of p80 form of tumor necrosis factor receptor by human immunodeficiency virus-1 tat gene
    • Pocsik E, Higuchi M, and Aggarwal BB: Down-modulation of cell surface expression of p80 form of tumor necrosis factor receptor by human immunodeficiency virus-1 tat gene. Lymphokine Cytokine Res 1992;11:317-325.
    • (1992) Lymphokine Cytokine Res , vol.11 , pp. 317-325
    • Pocsik, E.1    Higuchi, M.2    Aggarwal, B.B.3
  • 25
    • 0026446924 scopus 로고
    • Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression. Implications for AIDS-Kaposi's sarcoma pathogenesis
    • Barillari G, Buonaguro L, Filorelli V, Hoffman J, Michael F, Gallo RC, and Ensoli B: Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression. Implications for AIDS-Kaposi's sarcoma pathogenesis. J Immunol 1994;149: 3727-3734.
    • (1994) J Immunol , vol.149 , pp. 3727-3734
    • Barillari, G.1    Buonaguro, L.2    Filorelli, V.3    Hoffman, J.4    Michael, F.5    Gallo, R.C.6    Ensoli, B.7
  • 27
    • 0028127907 scopus 로고
    • Interleukin-1 increases protein kinase A activity by a cAMP-independent mechanism in AtT-20 cells
    • Gwosdow AR, O'Connell NA, and Abou-Samra AB: Interleukin-1 increases protein kinase A activity by a cAMP-independent mechanism in AtT-20 cells. Am J Physiol 1994;266:E79-E84.
    • (1994) Am J Physiol , vol.266
    • Gwosdow, A.R.1    O'Connell, N.A.2    Abou-Samra, A.B.3
  • 28
    • 0027513980 scopus 로고
    • Type specific stimulation of adenylyl cyclase by protein kinase C
    • Yoshimura M and Cooper DMF: Type specific stimulation of adenylyl cyclase by protein kinase C. J Biol Chem 1993;268:4604.
    • (1993) J Biol Chem , vol.268 , pp. 4604
    • Yoshimura, M.1    Cooper, D.M.F.2
  • 30
    • 0028271114 scopus 로고
    • Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells
    • Westendorp MO, Li-Weber M, Frank RW, and Krammer PH: Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells. J Virol 1994;68:4177-4185.
    • (1994) J Virol , vol.68 , pp. 4177-4185
    • Westendorp, M.O.1    Li-Weber, M.2    Frank, R.W.3    Krammer, P.H.4
  • 31
    • 0027217250 scopus 로고
    • Evidence for stimulation of the transforming growth factor B1 promoter by HIV-1 Tat in cells derived from CNS
    • Cupp C, Taylor JP, Khalili K, and Amini S: Evidence for stimulation of the transforming growth factor B1 promoter by HIV-1 Tat in cells derived from CNS. Oncogene 1993;8:2231-2236.
    • (1993) Oncogene , vol.8 , pp. 2231-2236
    • Cupp, C.1    Taylor, J.P.2    Khalili, K.3    Amini, S.4
  • 34
    • 0030914237 scopus 로고    scopus 로고
    • HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors
    • Ambrosino C, Ruocco MR, Chen X, Mallardo M, Baudi F, Trematerra S, Quinto F, Venuta S, and Scala G: HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors. J Biol Chem 1997;272(23): 14883-14892.
    • (1997) J Biol Chem , vol.272 , Issue.23 , pp. 14883-14892
    • Ambrosino, C.1    Ruocco, M.R.2    Chen, X.3    Mallardo, M.4    Baudi, F.5    Trematerra, S.6    Quinto, F.7    Venuta, S.8    Scala, G.9
  • 35
    • 0031067808 scopus 로고    scopus 로고
    • Prostaglandin F2 alpha stimulated interleukin-6 synthesis via activation of PKC in osteoblast-like cells
    • Kozawa O, Suzuki A, Tokuda H, and Uematsu T: Prostaglandin F2 alpha stimulated interleukin-6 synthesis via activation of PKC in osteoblast-like cells. Am J Physiol 1997;272(2Pt1):E208-211.
    • (1997) Am J Physiol , vol.272 , Issue.2 PART 1
    • Kozawa, O.1    Suzuki, A.2    Tokuda, H.3    Uematsu, T.4
  • 36
    • 0026451081 scopus 로고
    • Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y: Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992;258: 607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 37
    • 0028924021 scopus 로고
    • Human immunodeficiency virus Tat induces functional unresponsiveness in T cells
    • Chirmule N, Than S, Khan SA, and Pahwa S: Human immunodeficiency virus Tat induces functional unresponsiveness in T cells. J Virol 1995;69:492-498.
    • (1995) J Virol , vol.69 , pp. 492-498
    • Chirmule, N.1    Than, S.2    Khan, S.A.3    Pahwa, S.4
  • 38
    • 0027203061 scopus 로고
    • Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase a pathway in normal lymphocytes
    • Hofmann B, Nishanian P, Nguen T, Insixiengmay P, and Fahey JL: Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes. Proc Natl Acad Sci USA 1993;90:6676-6680.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6676-6680
    • Hofmann, B.1    Nishanian, P.2    Nguen, T.3    Insixiengmay, P.4    Fahey, J.L.5
  • 39
    • 0025342317 scopus 로고
    • Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C
    • Jacobovits A, Rosenthal A, and Capon DJ: Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C. EMBO J 1990;9:1165-1170.
    • (1990) EMBO J , vol.9 , pp. 1165-1170
    • Jacobovits, A.1    Rosenthal, A.2    Capon, D.J.3
  • 40
    • 0022631158 scopus 로고
    • Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters
    • Schleimer RP and Rutledge BK: Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters. J Immunol 1986;136:649-654.
    • (1986) J Immunol , vol.136 , pp. 649-654
    • Schleimer, R.P.1    Rutledge, B.K.2
  • 42
    • 0025761919 scopus 로고
    • Tumor necrosis factor induction of endothelial cell surface antigens is independent of protein kinase C activation or inactivation. Studies with phorbol myristate acetate and staurosporin
    • Ritchie AJ, Johnson DR, Ewenstein BM, Pober JS: Tumor necrosis factor induction of endothelial cell surface antigens is independent of protein kinase C activation or inactivation. Studies with phorbol myristate acetate and staurosporin. J Immunol 1991;146: 3056-3062.
    • (1991) J Immunol , vol.146 , pp. 3056-3062
    • Ritchie, A.J.1    Johnson, D.R.2    Ewenstein, B.M.3    Pober, J.S.4
  • 43
    • 0026532379 scopus 로고
    • Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICBM-1 induction
    • Myers CL, Desai SN, Schembri-King J, Letts GL, and Wallace RW: Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICBM-1 induction. Am J Physiol C 1992;262(2Pt1):C365-373.
    • (1992) Am J Physiol C , vol.262 , Issue.2 PART 1
    • Myers, C.L.1    Desai, S.N.2    Schembri-King, J.3    Letts, G.L.4    Wallace, R.W.5
  • 44
    • 0026710624 scopus 로고
    • Intercellular adhesion molecule-1 gene expression in human endothelial cells. Differential regulation by tumor necrosis factor-α and phorbol myristate acetate
    • Wertheimer ST, Myers CL, Wallace RW, and Parks T: Intercellular adhesion molecule-1 gene expression in human endothelial cells. Differential regulation by tumor necrosis factor-α and phorbol myristate acetate. J Biol Chem 1992;267:12030-12035.
    • (1992) J Biol Chem , vol.267 , pp. 12030-12035
    • Wertheimer, S.T.1    Myers, C.L.2    Wallace, R.W.3    Parks, T.4
  • 45
    • 0027474924 scopus 로고
    • Adhesion molecules involved in protein kinase A- and C-dependent lymphocyte adherence to microvascular endothelial cells
    • Turunen JP, Ustinov J, and Renkonen R: Adhesion molecules involved in protein kinase A- and C-dependent lymphocyte adherence to microvascular endothelial cells. Scand J Immunol 1993;37(3):282-288.
    • (1993) Scand J Immunol , vol.37 , Issue.3 , pp. 282-288
    • Turunen, J.P.1    Ustinov, J.2    Renkonen, R.3
  • 46
    • 0026729650 scopus 로고
    • TNFα-induced expression of endothelial adhesion molecules, ICAM-1 and VCAM-1, is linked to protein kinase C activation
    • Manila P, Majuri M-L, Mattila PS, and Renkonen R: TNFα-induced expression of endothelial adhesion molecules, ICAM-1 and VCAM-1, is linked to protein kinase C activation. Scand J Immunol 1992;36:159-165.
    • (1992) Scand J Immunol , vol.36 , pp. 159-165
    • Manila, P.1    Majuri, M.-L.2    Mattila, P.S.3    Renkonen, R.4
  • 47
    • 0025873774 scopus 로고
    • Role of protein kinase C and cyclic adenosine monophosphate in the regulation of tissue-type plasminogen activator, plasminogen activator inhibitor-1, and platelet-derived growth factor mRNA levels in human endothelial cells
    • Kooistra T, Bosma PJ, Toet K, Cohen LH, Griffioen M, van den Berg E, le Clercq L, and van Hinsbergh: Role of protein kinase C and cyclic adenosine monophosphate in the regulation of tissue-type plasminogen activator, plasminogen activator inhibitor-1, and platelet-derived growth factor mRNA levels in human endothelial cells.Arteriosclerosis Thrombosis 1991;11:1042-1052.
    • (1991) Arteriosclerosis Thrombosis , vol.11 , pp. 1042-1052
    • Kooistra, T.1    Bosma, P.J.2    Toet, K.3    Cohen, L.H.4    Griffioen, M.5    Van Den Berg, E.6    Le Clercq, L.7    Van Hinsbergh8
  • 48
    • 0022129496 scopus 로고
    • Tumor-promoting phorbol esters induce angiogenesis in vitro
    • Montesano R and Orci L: Tumor-promoting phorbol esters induce angiogenesis in vitro. Cell 1985;42:469-477.
    • (1985) Cell , vol.42 , pp. 469-477
    • Montesano, R.1    Orci, L.2
  • 49
    • 0025250519 scopus 로고
    • Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells
    • Araki S, Shimada Y, Kaji K, and Hayashi H: Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells. Biochem Biophys Res Commun 1990;172:1081-1085.
    • (1990) Biochem Biophys Res Commun , vol.172 , pp. 1081-1085
    • Araki, S.1    Shimada, Y.2    Kaji, K.3    Hayashi, H.4
  • 50
    • 0023803278 scopus 로고
    • Phorbol ester reduces number of heparin-binding growth-factor receptors in human adult endothelial cells
    • Hoshi H, Kan M, Mioh H, Chen J, and McKeehan WL: Phorbol ester reduces number of heparin-binding growth-factor receptors in human adult endothelial cells. FASEB J. 1988;2:2797-2800.
    • (1988) FASEB J. , vol.2 , pp. 2797-2800
    • Hoshi, H.1    Kan, M.2    Mioh, H.3    Chen, J.4    McKeehan, W.L.5
  • 51
    • 0025203931 scopus 로고
    • Protein kinase C inhibitors block the enhanced expression of intercellular adhesion molecule-1 on endothelial cells activated by interleukin-1, lipopolysaccharide and tumor necrosis factor
    • Lane TA, Lamkin GE, and Wancewicz EV: Protein kinase C inhibitors block the enhanced expression of intercellular adhesion molecule-1 on endothelial cells activated by interleukin-1, lipopolysaccharide and tumor necrosis factor. Biochem Biophys Res Commun 1990;172:1273-1281.
    • (1990) Biochem Biophys Res Commun , vol.172 , pp. 1273-1281
    • Lane, T.A.1    Lamkin, G.E.2    Wancewicz, E.V.3
  • 52
    • 0023796127 scopus 로고
    • Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator-1 from human endothelial cells
    • Santell L and Levin EG: Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator-1 from human endothelial cells. J Biol Chem 1988;263:16802-16808.
    • (1988) J Biol Chem , vol.263 , pp. 16802-16808
    • Santell, L.1    Levin, E.G.2
  • 53
    • 0024425865 scopus 로고
    • Histamine and inositol phosphate accumulation in endothelium: CAMP and a G protein
    • Carson MR, Shasby SS, and Shasby DM: Histamine and inositol phosphate accumulation in endothelium: cAMP and a G protein. Am J Physiol 1989;257:L259-L264.
    • (1989) Am J Physiol , vol.257
    • Carson, M.R.1    Shasby, S.S.2    Shasby, D.M.3
  • 54
    • 0026639326 scopus 로고
    • Intracellular signal transduction and the control of endothelial permeability
    • Editorial
    • Hoek JB: Editorial: Intracellular signal transduction and the control of endothelial permeability. Lab Invest 1992;67:1-4.
    • (1992) Lab Invest , vol.67 , pp. 1-4
    • Hoek, J.B.1
  • 55
    • 0028323256 scopus 로고
    • Structure and function of cyclic nucleotide-dependent protein kinases
    • Francis SH and Corbin JD: Structure and function of cyclic nucleotide-dependent protein kinases. Annu Rev Physiol 1994;56: 237-272.
    • (1994) Annu Rev Physiol , vol.56 , pp. 237-272
    • Francis, S.H.1    Corbin, J.D.2
  • 56
    • 0027521591 scopus 로고
    • The ways in which hormones change cyclic adenosine 3′,5′-monophosphate-dependent protein kinase subunits, and how such changes affect cell behavior
    • Spaulding SW: The ways in which hormones change cyclic adenosine 3′,5′-monophosphate-dependent protein kinase subunits, and how such changes affect cell behavior. Endocrine Rev 1993;14: 632-650.
    • (1993) Endocrine Rev , vol.14 , pp. 632-650
    • Spaulding, S.W.1
  • 58
    • 0022363890 scopus 로고
    • Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line
    • Rebois RV and Patel J: Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line. J Biol Chem 1985;260:8026-8031.
    • (1985) J Biol Chem , vol.260 , pp. 8026-8031
    • Rebois, R.V.1    Patel, J.2
  • 59
    • 0028930949 scopus 로고
    • Adenylyl cyclase isoforms are differentially expressed in primary cultures of endothelial cells and whole tissue homogenates from various rat tissues
    • Manolopoulos VG, Liu J, Unsworth BR, and Lelkes PI: Adenylyl cyclase isoforms are differentially expressed in primary cultures of endothelial cells and whole tissue homogenates from various rat tissues. Biochem Biophys Res Commun 1985;208:323-331.
    • (1985) Biochem Biophys Res Commun , vol.208 , pp. 323-331
    • Manolopoulos, V.G.1    Liu, J.2    Unsworth, B.R.3    Lelkes, P.I.4
  • 60
    • 0028157915 scopus 로고
    • Endothelin-1 receptor binding and cellular signal transduction in cultured human brain endothelial cells
    • Stanimirovic DB, Yamamoto T, Uematsu S, and Spatz M: Endothelin-1 receptor binding and cellular signal transduction in cultured human brain endothelial cells. J Neurochem 1994;62: 592-601.
    • (1994) J Neurochem , vol.62 , pp. 592-601
    • Stanimirovic, D.B.1    Yamamoto, T.2    Uematsu, S.3    Spatz, M.4
  • 61
    • 0027716596 scopus 로고
    • Inhibition by cAMP of Ras-dependent activation of Raf
    • Cook SJ and McCormick F: Inhibition by cAMP of Ras-dependent activation of Raf. Science 1993;262:1069-1077.
    • (1993) Science , vol.262 , pp. 1069-1077
    • Cook, S.J.1    McCormick, F.2
  • 62
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signalling pathway by adenosine 3′,5′-monophosphate
    • Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ, and Sturgill TW: Inhibition of the EGF-activated MAP kinase signalling pathway by adenosine 3′,5′-monophosphate. Science 1993;262: 1065-1069.
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 63
    • 0023191793 scopus 로고
    • Rapid enhancement of β2-interferon/B cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerol and the calcium ionophore A23187
    • Sehgal PB, Walther Z, and Tamm I: Rapid enhancement of β2-interferon/B cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerol and the calcium ionophore A23187. Proc Natl Acad Sci USA 1987;84:3663-3667.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3663-3667
    • Sehgal, P.B.1    Walther, Z.2    Tamm, I.3
  • 64
    • 0023951336 scopus 로고
    • Synthesis of interleukin 6 (interferon β2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP
    • Zhang Y, Lin J-X, and Viliek J: Synthesis of interleukin 6 (interferon β2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP. J Biol Chem 1988;263:6177-6182.
    • (1988) J Biol Chem , vol.263 , pp. 6177-6182
    • Zhang, Y.1    Lin, J.-X.2    Viliek, J.3
  • 65
    • 0025280023 scopus 로고
    • Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence
    • Zhang Y, Lin J-X, and Viliek J: Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a κB-like sequence. Mol Cell Biol 1990;10:3818-3823.
    • (1990) Mol Cell Biol , vol.10 , pp. 3818-3823
    • Zhang, Y.1    Lin, J.-X.2    Viliek, J.3
  • 66
    • 0030253214 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-α and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells
    • Duchini A, Govindarajan S, Sanlucci M, Zampi G, and Hofman FM: Effects of tumor necrosis factor-α and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells. J Invest Med 1996;44:474-482.
    • (1996) J Invest Med , vol.44 , pp. 474-482
    • Duchini, A.1    Govindarajan, S.2    Sanlucci, M.3    Zampi, G.4    Hofman, F.M.5
  • 67
    • 0024339530 scopus 로고
    • On the cellular source and function of interleukin 6 in the central nervous system in viral diseases
    • Frei K, Malipiero UV, Leist TP, Zinkernagel RM, Schwab ME, and Fontana A: On the cellular source and function of interleukin 6 in the central nervous system in viral diseases. Eur J Immunol 1989;19:689-694.
    • (1989) Eur J Immunol , vol.19 , pp. 689-694
    • Frei, K.1    Malipiero, U.V.2    Leist, T.P.3    Zinkernagel, R.M.4    Schwab, M.E.5    Fontana, A.6
  • 68
    • 0024358854 scopus 로고
    • Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells
    • Tamm I, Cardinale I, Krueger J, Murphy JS, May LT, and Sehgal PB: Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells. J Exp Med 1989; 170:1649-1669.
    • (1989) J Exp Med , vol.170 , pp. 1649-1669
    • Tamm, I.1    Cardinale, I.2    Krueger, J.3    Murphy, J.S.4    May, L.T.5    Sehgal, P.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.