Mode of action of the anticancer quassinoids - Inhibition of the plasma membrane NADH oxidase

Life Sciences

Volumn 63, Issue 7, 1998, Pages 595-604

  Morré, D James ^a   Grieco, Paul A ^b   Morré, Dorothy M ^b  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Antitumor agents; Glaucarubolone; Growth inhibition; HeLa cells; Liver; NADH oxidase; Plasma membranes; Quassinoids

Indexed keywords

ANTINEOPLASTIC AGENT; GLAUCARUBOLONE; OXIDOREDUCTASE INHIBITOR; QUASSINOID DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; ENZYME INHIBITION; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; LIVER MEMBRANE; MEMBRANE VESICLE; NONHUMAN; OXIDATION REDUCTION REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL MEMBRANE; GLAUCARUBIN; HELA CELLS; HUMANS; LIVER; MOLECULAR WEIGHT; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; RATS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032503953     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00310-5     Document Type: Article

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