A versatile procedure for the generation of nucleoside 5'- carboxylic acids using nucleoside oxidase

Tetrahedron

Volumn 54, Issue 28, 1998, Pages 8171-8182

  Mahmoudian, Mahmoud ^a   Rudd, Brian A M ^a   Cox, Brian ^a   Drake, Chris S ^a   Hall, Richard M ^a   Stead, Paul ^a   Dawson, Michael J ^a   Chandler, Malcolm ^a   Livermore, David G ^a   Turner, Nicholas J ^b   Jenkins, Gareth ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; NUCLEOSIDE; NUCLEOSIDE 5 CARBOXYLIC ACID; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN SYNTHESIS; STENOTROPHOMONAS MALTOPHILIA;

NEGIBACTERIA; STENOTROPHOMONAS MALTOPHILIA;

EID: 0032499993     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)00456-6     Document Type: Article

References (16)

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11. 9. Adenosine N-oxide (5), was obtained from Sigma.
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13. 11. Methyl isoguanosine (6) was synthesised in one step from 5-amino-1-β-D-ribofuranosyl-4-imidazolecarboxamide using the method of Chem, J. W.; Lin, G. S.; Chen, C. S.; Townsend, L. B. J. Org. Chem. 1991, 56, 4213-18.
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16. 14. For the synthesis of 10 see; Ayres, B.E.; Gregson, M.; Ewan, G.B.; Chandler, M. PCT Int. Appl., WO 9602543, 1996.