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Volumn 39, Issue 15, 1998, Pages 2195-2198

Solid-phase C-acylation of active methylene compounds

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; CHEMICAL AGENT; RESIN; TRIETHYLAMINE;

EID: 0032499088     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00173-7     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 4244006369 scopus 로고    scopus 로고
    • 1. For recent thematic journal issues devoted to combinatorial chemistry, see: (a) Chem. Rev. 1997, 97, #2.
    • (1997) Chem. Rev. , vol.97 , pp. 2
  • 20
    • 0001246036 scopus 로고
    • 6. We are not aware of any recent publications on solid-phase C-acylation. Earlier reports have described acylation of ester enolates: (a) Patchornik, A.; Kraus, M. A. J. Am. Chem. Soc. 1970, 92, 7587-7589.
    • (1970) J. Am. Chem. Soc. , vol.92 , pp. 7587-7589
    • Patchornik, A.1    Kraus, M.A.2
  • 23
    • 0003592858 scopus 로고
    • Benjamin: New York
    • 7. For reviews on C-acylation of active methylene compounds, see: (a) House, H. O. Modern Synthetic Reactions (2nd ed.); Benjamin: New York, 1972; pp. 734-765 and 772-786.
    • (1972) Modern Synthetic Reactions (2nd Ed.) , pp. 734-765
    • House, H.O.1
  • 24
    • 0000010274 scopus 로고
    • Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford
    • (b) Davies, B. R.; Garratt, P. J. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, 1991; Vol. 2, pp. 795-863.
    • (1991) Comprehensive Organic Synthesis , vol.2 , pp. 795-863
    • Davies, B.R.1    Garratt, P.J.2
  • 30
    • 0019511115 scopus 로고
    • 10. The nature of the acylating agent under these conditions is not fully understood, and may either be the acyl cyanide or the acyl phosphate: Hamada, Y.; Ando, K.; Shiori, T. Chem. Pharm. Bull. 1981, 29, 259-261.
    • (1981) Chem. Pharm. Bull. , vol.29 , pp. 259-261
    • Hamada, Y.1    Ando, K.2    Shiori, T.3
  • 31
    • 0010553766 scopus 로고    scopus 로고
    • note
    • 2), concentrated, and chromatographed (silica, hexanes/ethyl acetate 75:25) to yield 12.5 mg of benzoylacetonitrile.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.