The protective role of mild acidic pH shifts on synaptic NMDA current in hippocampal slices

Brain Research

Volumn 786, Issue 1-2, 1998, Pages 128-132

  Saybasili, Hale ^a  

^a BOGAZICI UNIVERSITY   (Turkey)

Author keywords

Extracellular pH change; Hippocampal slice; Hypoxia ischemia; NMDA receptor; Patch clamp tight seal whole cell recording

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL PH; HIPPOCAMPUS; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

EID: 0032498934     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01461-3     Document Type: Article

References (28)

1. [1] P. Ascher, L. Nowak, Electrophysiological studies of NMDA receptors, TINS 10 (1987) 284-288.
2. [2] S.Y. Assaf, S.H. Chung, Release of endogenous zinc from brain tissue during activity, Nature 308 (1984) 734-736.
3. [3] M. Balestrino, G.G. Somjen, Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat, J. Physiol. (London) 396 (1988) 247-266.
4. [4] M. Benveniste, M.L. Mayer, Multiple effect of spermine on NMDA receptor responses of rat cultured hippocampal neurons, J. Physiol. (London) 464 (1993) 131-163.
5. [5] T.V.P. Bliss, G.L. Collingridge, A synaptic model of memory: long-term potentiation in the hippocampus, Nature 361 (1993) 31-39.
6. [6] M. Chesler, The regulation and modulation of pH in the nervous system, Prog. Neurobiol. 34 (1990) 401-427.
7. [7] D.W. Choi, J. Koh, S. Peters, Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists, J. Neurosci. 8 (1988) 185-196.
8. [8] A.C. Foster, G.E. Fagg, Acidic amino acid binding sites in mammalian neuronal membrane: their characteristics and relationship to synaptic receptors, Brain Res. Rev. 7 (1984) 103-164.
9. [9] J.J. Hablitz, I.A. Langmoen, Excitation of hippocampal pyramidal cells by glutamate in the guinea-pig and rat, J. Physiol. (London) 325 (1982) 317-331.
10. O2 of the extracellular space during ischemia of primate cerebral cortex, J. Cereb. Blood Flow Metab. 7 (1987) 599-604.
11. [11] S. Lipton, Prospects for clinically tolerated NMDA antagonists: open channel blockers and alternative redox states of nitric oxide, TINS 16 (1994) 185-196.
12. [12] A.B. MacDermott, M.L. Mayer, G.L. Westbrook, S.J. Smith, J.L. Barker, NMDA activation increases cytoplasmic calcium concentration in cultured spinal cord neurons, Nature 321 (1986) 519-522.
13. [13] I. Mody, F. MacDonald, NMDA receptor-dependent excitotoxicity: the role of intracellular calcium release, TIPS 16 (1995) 356-359.
14. 3H] glutamate binding sites, Nature 306 (1983) 719-721.
15. [15] L. Nowak, P. Bregestovski, P. Ascher, Magnesium gates glutamate-activated channels in mouse central neurons, Nature 307 (1984) 462-465.
16. [16] T. Ogata, Y. Nakamura, T. Shibata, K. Kataoka, Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation, J. Neurochem. 58 (1992) 1957-1959.
17. [17] J.V. Olney, Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate, Science 164 (1969) 719-721.
18. 3H]-D-APS binding sites in rat brain membranes, Nature 307 (1984) 460-462.
19. [19] I.J. Reynolds, T.G. Hastings, Glutamate induces the production of reactive oxygen species in cultured forebrain neurons with NMDA receptor activation, J. Neurosci. 15 (1995) 3318-3327.
20. [20] H. Saybasili, D.R. Stevens, H.L. Haas, pH-dependent modulation of N-methyl-D-aspartate receptor-mediated synaptic currents by histamine in rat hippocampus in vitro, Neurosci. Lett. 199 (1995) 225-227.
21. [21] B.K. Siesjo, K.I. Katsura, T. Kristian, P.-A. Li, P. Siesjo, Molecular mechanisms of acidosis mediated damage, Acta Neurochir. 66 (1996) 8-14, Suppl.
22. [22] R.P. Simon, J.H. Swan, T. Griffiths, B.S. Meldrum, Blockade of NMDA receptors may protect against ischemie damage in the brain, Science 226 (1984) 850-852.
23. [23] L.R. Squire, S. Zola-Morgan, Memory: brain systems and behaviour, TINS 11 (1988) 170-175.
24. [24] T. Taira, S. Smirnov, J. Voipio, K. Kaila, Intrinsic proton modulation of excitatory transmission in rat hippocampal slices, NeuroReport 4 (1993) 93-96.
25. +, Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 6445-6449.
26. [26] S.F. Traynelis, S.G. Cull-Candy, Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons, Nature 345 (1990) 347-350.
27. [27] S.F. Traynelis, M. Hartley, S.F. Heinemann, Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines, Science 268 (1995) 873-875.
28. [28] L. Vyklicky, V. Vlachova, J. Krusek, The effect of external pH changes on responses to excitatory amino acids in mouse hippocampal neurons, J. Physiol. (London) 430 (1990) 497-517.