Effects of extracellular calcium and magnesium on central respiratory control in the brainstem-spinal cord of neonatal rat

Brain Research

Volumn 786, Issue 1-2, 1998, Pages 194-204

  Kuwana, Shun Ichi ^a   Okada, Yasumasa ^b   Natsui, Teijiro ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Calcium; Central chemosensitivity; Control of breathing; Isolated brainstem spinal cord preparation; Magnesium; Neonatal rat

Indexed keywords

CALCIUM ION; MAGNESIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; BREATHING PATTERN; BREATHING RATE; CALCIUM TRANSPORT; CHANNEL GATING; CONTROLLED STUDY; EXTRACELLULAR FLUID; MEDULLA OBLONGATA; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; SPINAL CORD; SYNAPTIC TRANSMISSION; VENTRAL ROOT;

ANIMALS; ANIMALS, NEWBORN; BRAIN STEM; CALCIUM; CHEMORECEPTORS; DENERVATION; EXTRACELLULAR SPACE; MAGNESIUM; MEDULLA OBLONGATA; MICROELECTRODES; NEURONS; OSMOLAR CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY PHYSIOLOGY; SPINAL CORD;

EID: 0032498881     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01476-5     Document Type: Article

References (42)

1. 2+ on synaptic and neural function in the CA1 region of the hippocampal slice, Brain Res. 377 (1986) 229-239.
2. 2, Pflügers Arch. 348 (1974) 33-50.
3. [3] A. Berkenbosch, P.M. Quanjer, J. de Goede, G.J. Tammeling, The influence of CSF calcium and magnesium on the ventilatory response to carbon dioxide during hyperoxia, Pflügers Arch. 365 (1976) 151-157.
4. [4] E. Bernard, L. Urbán, G.G. Somjen, Spinal dorsal horn neurons in elevated extracellular calcium: cell properties and spontaneous discharges, Brain Res. 521 (1990) 161-166.
5. [5] J. Berndt, A. Fenner, K. Berger, Influence of calcium and magnesium on the respiratory response to changes in CSF pH, Respir. Physiol. 7 (1969) 216-229.
6. [6] D. Bingmann, R.E. Baker, D. Ballantyne, D. Jones, G. Widman, Suppression of rhythmic discharges of medullary neurones in organotypic cultures of new-born rats by calcium antagonists, Neurosci. Lett. 199 (1995) 187-190.
7. [7] G. Czéh, G.G Somjen, Changes in extracellular calcium and magnesium and synaptic transmission in isolated mouse spinal cord, Brain Res. 486 (1989) 274-285.
8. [8] G. Czéh, G.G. Somjen, Spontaneous activity induced in isolated mouse spinal cord by high extracellular calcium and by low extracellular magnesium, Brain Res. 495 (1989) 89-99.
9. [9] G.E. Cordingley, G.G. Somjen, The clearing of excess potassium from extracellular space in spinal cord and cerebral cortex, Brain Res. 151 (1978) 291-306.
10. [10] J. Duffin, K. Ezure, J. Lipski, Breathing rhythm generation: focus on the rostral ventrolateral medulla, NIPS 10 (1995) 133-140.
11. [11] J.L. Feldman, Y. Li, G.D. Funk, J.C. Smith, X.-W. Dong, S.W. Johnson, J. Lai, S. Hsu, S. Tonegawa, Neonatal mice lacking functional NMDA receptors generate respiratory oscillations in vivo and in vitro, Soc. Neurosci. 19 (1993) 925, Abstract.
12. [12] B. Frankenhaeuser, A.L. Hodgkin, The action of calcium on the electrical properties of squid axons, J. Physiol. 137 (1957) 218-244.
13. + on spontaneous neuronal activity in the surface layer of the rat medulla oblongata in vitro, Pflügers Arch. 371 (1977) 125-134.
14. [14] G.D. Funk, J.L. Feldman, Generation of respiratory rhythm and pattern in mammals: insights from developmental studies, Curr. Opin. Neurobiol. 5 (1995) 778-785.
15. [15] J.J. Greer, J.C. Smith, J.L. Feldman, Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat, J. Physiol. 437 (1991) 727-749.
16. [16] B. Hille, Ionic Channels of Excitable Membranes, Sinauer Associate, Sunderland, MA, USA, 1992.
17. [17] S.M. Johnson, J.C. Smith, G.D. Funk, J.L. Feldman, Pacemaker behavior of respiratory neurons in medullary slices from neonatal rat, J. Neurophysiol. 72 (1994) 2598-2608.
18. [18] A. Kawai, D. Ballantyne, K. Mückenhoff, P. Scheid, Chemosensitive medullary neurones in the brainstem-spinal cord preparation of the neonatal rat, J. Physiol. 492 (1996) 277-292.
19. [19] J.P. Kiley, F.L. Eldridge, D.E. Millhorn, The roles of medullary extracellular and cerebrospinal fluid pH in control of respiration, Respir. Physiol. 59 (1985) 117-130.
20. [20] A. Konnerth, U. Heinemann, Y. Yaari, Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro, J. Neurophysiol. 56 (1986) 409-423.
21. [21] D.S. Krafte, R.S. Kass, Hydrogen ion modulation of Ca channel current in cardiac ventricular cells: Evidence for multiple mechanisms, J. Gen. Physiol. 91 (1988) 641-657.
22. [22] S. Kuwana, Y. Okada, T. Natsui, Extracellular calcium and central control of respiration in the isolated brainstem-spinal cord of the neonatal rat, FASEB J. 10 (1996) A407, Abstract.
23. [23] I. Leusen, Regulation of cerebrospinal fluid composition with reference to breathing, Physiol. Rev. 52 (1972) 1-56.
24. 2+ on channel gating and steady-state responses of the NMDA receptor in cultured rat neurons, J. Physiol. 491 (1996) 137-150.
25. 2+ of NMDA responses in spinal cord neurones, Nature 309 (1984) 261-263.
26. [26] G. Morawietz, K. Ballanyi, S. Kuwana, D.W. Richter, Oxygen supply and ion homeostasis of the respiratory network in the in vitro perfused brainstem of adult rats, Exp. Brain Res. 106 (1995) 265-274.
27. [27] T. Murakoshi, T. Suzue, S. Tamai, A pharmacological study on respiratory rhythm in the isolated brainstem-spinal cord preparation of the newborn rat, Br. J. Pharmacol. 86 (1985) 95-104.
28. [28] C. Nicholson, G. Ten Bruggencate, H. Stöckle, R. Steinberg, Calcium and potassium changes in extracellular microenvironment of cat cerebellar cortex, J. Neurophysiol. 41 (1978) 1026-1039.
29. [29] Y. Okada, A. Kawai, K. Mückenhoff, P. Scheid, Extracellular potassium and respiratory activity in the brainstem-spinal cord preparation of the neonatal rat, FASEB J. 7 (1993) A401, Abstract.
30. O2 in the isolated brain stem-spinal cord of the neonatal rat, Respir. Physiol. 93 (1993) 315-326.
31. [31] H. Onimaru, Studies of the respiratory center using isolated brainstem-spinal cord preparations, Neurosci. Res. 21 (1995) 183-190.
32. [32] H. Onimaru, A. Arata, I. Homma, Intrinsic burst generation of preinspiratory neurons in the medulla of brainstem-spinal cord preparations isolated from newborn rats, Exp. Brain Res. 106 (1995) 57-68.
33. [33] H. Onimaru, K. Ballanyi, D.W. Richter, Calcium-dependent responses in neurons of the isolated respiratory network of newborn rats, J. Physiol. 491 (1996) 677-695.
34. [34] M. Puka-Sundvall, H. Hagberg, P. Andiné, Changes in extracellular calcium concentration in the immature rat cerebral cortex during anoxia are not influenced by MK-801, Dev. Brain Res. 77 (1994) 146-150.
35. [35] D.W. Richter, J. Champagnat, T. Jacquin, R. Benacka, Calcium currents and calcium dependent potassium currents in mammalian medullary respiratory neurones, J. Physiol. 470 (1993) 23-33.
36. [36] J.C. Smith, H.H. Ellenberger, K. Ballanyi, D.W. Richter, J.L. Feldman, Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals, Science 254 (1991) 726-729.
37. [37] B.T. Stokes, P. Fox, G. Hollinden, Extracellular calcium activity in the injured spinal cord, Exp. Neurol. 80 (1983) 561-572.
38. [38] T. Suzue, Respiratory rhythm generation in the in vitro brain stem-spinal cord preparation of the neonatal rat, J. Physiol. 354 (1984) 173-183.
39. [39] K. Takahashi, D.B. Dixon, D.R. Copenhagen, Modulation of a sustained calcium current by intracellular pH in horizontal cells of fish retina, J. Gen. Physiol. 101 (1993) 695-714.
40. [40] A. Völker, K. Ballanyi, D.W. Richter, Anoxic disturbance of the isolated respiratory network of neonatal rats, Exp. Brain Res. 103 (1995) 9-19.
41. [41] A. Wald, G.M. Hochwald, M. Gandhi, Evidence for the movement of fluid macromolecules and ions from the brain extracellular space to the CSF, Brain Res. 151 (1978) 283-290.
42. [42] Z.-G. Xiong, W.-Y. Lu, J.F. MacDonald, Extracellular calcium sensed by a novel cation channel in hippocampal neurons, Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 7012-7017.