Reaction of oxidized glutathione with cis- and trans-diamminedichloroplatinum(II) and their aquated complexes through the disulfide bond

International Journal of Pharmaceutics

Volumn 161, Issue 1, 1998, Pages 15-21

  Ohta, Naoko ^a   Inagaki, Kenji ^b   Muta, Hiroyuki ^a   Yotsuyanagi, Toshihisa ^a   Matsuo, Takakazu ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b SEIREI CHRISTOPHER UNIVERSITY   (Japan)

Author keywords

cis Diamminedichloroplatinum(II); Cisplatin; Disulfide bond; Drug interaction; Metabolism; Oxidized glutathione; Reduced glutathione

Indexed keywords

CISPLATIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROXIDE; LIGAND; PLATINUM COMPLEX; WATER;

ARTICLE; CHEMICAL REACTION; CONJUGATION; DISULFIDE BOND; PH; PRIORITY JOURNAL; TEMPERATURE;

EID: 0032498571     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00323-2     Document Type: Article

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