Molecular cloning in the marmoset shows that semenogelin is not the precursor of the TRH-like peptide pGlu-Glu-Pro amide

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1387, Issue 1-2, 1998, Pages 143-152

  Huber, Ariana E ^a   Fraser, Hamish ^b   Del Rio Garcia, Jesus ^c   Kreil, Günther ^a   Smyth, Derek G ^a,c  

^a Institute of Molecular Biology Salzburg   (Austria)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF MURCIA   (Spain)

Author keywords

Marmoset; Pyroglutamylglutamylprolineamide; Semenogelin; TRH like peptide

Indexed keywords

PEPTIDE; PROTEIN PRECURSOR; PROTIRELIN; PYROGLUTAMYLGLUTAMYLPROLINAMIDE; SEMENOGELIN; TRH LIKE PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; ION EXCHANGE CHROMATOGRAPHY; MALE; MARMOSET; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PANCREAS; PRIORITY JOURNAL; PROSTATE; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SEMINAL PLASMA; SPERMATOZOON CAPACITATION; THYROID GLAND; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALLITHRIX; CLONING, MOLECULAR; GONADAL STEROID HORMONES; HUMANS; MALE; MAMMALS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROSTATE; PROTEIN PRECURSORS; PYRROLIDONECARBOXYLIC ACID; RNA, MESSENGER; SEMEN; SEMINAL VESICLE SECRETORY PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; THYROTROPIN-RELEASING HORMONE; TRYPSIN;

CALLITHRIX JACCHUS; MARMOSETS; ORYCTOLAGUS CUNICULUS;

EID: 0032497326     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(98)00116-2     Document Type: Article

References (32)

1. 2 (thyrotropin-releasing hormone) occur in rat prostate. Peptides. 4:1983;915-919.
2. Pekary A.E., Hershman J.M., Friedman S. Human semen contains thyrotropin-releasing hormone (TRH), a TRH-homologous peptide, and TRH-binding substance. J. Androl. 4:1983;399-407.
3. Rui H., Welinder B.S., Purvis K., Dolva O. Thyrotropin-releasing hormone in human ejaculate. J. Endocrinol. 114:1987;329-334.
4. Cockle S.M., Aitken A., Beg F., Smyth D.G. A novel peptide, pyroglutamylglutamylproline amide, in the rabbit prostate complex, structurally related to thyrotropin-releasing hormone. J. Biol. Chem. 264:1989;7788-7791.
5. Khan Z., Aitken A., del Rio Garcia J., Smyth D.G. Isolation and identification of two neutral thyrotropin-releasing hormone-like peptides, pyroglutamylphenylalanineproline amide and pyroglutamyl-glutamineproline amide, from human seminal fluid. J. Biol. Chem. 267:1992;7464-7467.
6. Green C.M., Cockle S.M., Watson P.F., Fraser L.R. Stimulating effects of pyroglutamylglutamylproline amide, a prostatic TRH-like tripeptide, on mouse sperm capacitation and fertility ability in vitro. Mol. Reprod. Dev. 38:1994;215-221.
7. Green C.M., Cockle S.M., Watson P.F., Fraser L.R. Fertilization promoting peptide, a tripeptide similar to thyrotropin-releasing hormone, stimulates the capacitation and fertilizing ability of human spermatozoa in vitro. Hum. Reprod. 11:1996;830-836.
8. A. Cremades, R. Peñafiel, V. Rausell, J. del Rio-Garcia, D.G. Smyth, The TRH-like peptides pGlu-Phe-Pro amide and pGlu-Glu-Pro amide increase plasma T3 levels in the mouse; the activity is sensitive to testosterone, Eur. J. Pharmacol., submitted.
9. del Rio-Garcia J., Sanchez-Alonso R., Martinez J.A., Lopez-Ortega M.M., Brugger S., Brugger A.J., Smyth D.G. Effects of TRH-like peptides on locomotor activity of the rat. Meth. Find. Exp. Clin. Pharmacol. 16:1994;62.
10. Khan Z., Smyth D.G. Isolation and identification of N-terminally extended forms of 5-oxoprolylglutamylproline amide (Glp-Glu-Pro NH2), a thyrotropin-releasing hormone (TRH)-like peptide present in human semen. Eur. J. Biochem. 212:1993;35-40.
11. Lilja H., Abrahamson P.A., Lundwall A. Semenogelin, the predominant protein in human semen. J. Biol. Chem. 264:1989;1894-1900.
12. Ulvsbäck M., Lazure C., Lilja H., Spurr N.K., Gopal Rao V.V.N., Löffler C., Hansmann Y., Lundwall A. Gene structure of semenogelin I and II; the predominant proteins in human semen are encoded by two homologous genes on chromosome 20. J. Biol. Chem. 267:1992;18080-18084.
13. A. Huber, G. Kreil, D.G. Smyth, B. Cooke, H.M. Fraser, J. Frick, J. del Rio-Garcia, TRH-like peptides in testis and Leydig cells, in: R. Solberg, V. Hansson (Eds.), 9th European Workshop on Molecular and Cellular Endocrinology of the Testis, Geilo, Norway, 1996, C7.
14. Huber A., Kreil G., Smyth D.G., Cooke B., Fraser H.M., Frick J., del Rio-Garcia J. TRH-like peptides in testis and Leydig cells. Int. J. Androl. 20:(Suppl. 1):1997;18.
15. Bilek R., Bradbury A.F., Smyth D.G. Synthesis and high-performance liquid chromatographic purification of tritiated thyrotropin-releasing hormone-like peptides. J. Chromatogr. 656:1994;115-118.
16. Fraser H.M., McNeilly A.S. Effect of chronic immunoneutralization of thyrotropin-releasing hormone on the hypothalamo-pituitary-thyroid axis, prolactin, and reproductive function in the ewe. Endocrinology. 111:1982;1964-1973.
17. del Rio-Garcia J., Smyth D.G. Distribution of pyroglutamylpeptide amides related to thyrotropin-releasing hormone in the central nervous system and periphery of the rat. J. Endocrinol. 127:1990;445-450.
18. Bilek R., Gkonos P.J., Tavianini M.A., Smyth D.G., Roos B.A. The thyrotropin-releasing hormone (TRH)-like peptides in rat prostate are not formed by expression of the TRH gene but are suppressed by thyroid hormone. J. Endocrinol. 132:1992;177-184.
19. Linden H., del Rio-Garcia J., Huber A., Kreil G., Smyth D.G. The TRH-like peptides in rabbit testis are different from the TRH-like peptide in the prostate. FEBS Lett. 379:1996;11-14.
20. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
21. Richter K., Egger R., Kreil G. D-Alanine in the frog skin peptide dermorphin is derived from L-alanine in the precursor. Science. 238:1987;200-202.
22. Gubler U., Chua A.O., Hoffmann B.J., Collier K.J., Eng J. Cloned cDNA to cholecystokinin mRNA predicts an identical preprocholecystokinin in pig brain and gut. Proc. Natl. Acad. Sci. USA. 81:1984;4307-4311.
23. Feinberg A.P., Vogelstein B. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 137:1984;266-267.
24. Sanger F., Coulsen A.R., Barrell B.G., Smith A.J.J., Roe B.A. Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J. Mol. Biol. 143:1980;161-164.
25. Pappu H.R., Hirnki C. RNA gel electrophoresis. Focus. 11:1989;6-7.
26. Church H.R., Gilbert W. Genomic sequencing. Proc. Natl. Acad. Sci. USA. 81:1984;1991-1995.
27. Gmachl M., Kreil G. The precursors of the bee venom constituents apamin and MCD peptide are encoded by two genes in tandem which share the same 3′-exon. J. Biol. Chem. 270:1995;12704-12708.
28. Suchanek G., Kreil G. Translation of melittin RNA in vitro yields a product terminating with glutaminyl glycine rather than glutamineamide. Proc. Natl. Acad. Sci. USA. 74:1977;975-978.
29. Bradbury A.F., Finnie M.D.A., Smyth D.G. Mechanism of C-terminal amide formation by pituitary enzymes. Nature. 298:1982;686-689.
30. Lilja H., Laurell C.B., Jeppson J.O. Characterization of the predominant basic protein in human seminal plasma, one cleavage product of the major seminal vesicle protein. Scand. J. Clin. Lab. Invest. 44:1984;439-446.
31. Bradbury A.F., Smyth D.G. Peptide amidation. Trends Biochem. Sci. 16:1991;112-115.
32. Docherty K., Steiner D.F. Post-translational proteolysis in polypeptide hormone biosynthesis. Annu. Rev. Physiol. 44:1982;625-638.