Stabilizing properties of copolymers adsorbed on heterogeneous surfaces: A model for the interactions between a polymer-coate influenza virus and a cell

Macromolecules

Volumn 31, Issue 18, 1998, Pages 6369-6379

  Balazs, Anna C ^a   Singh, Chandralekha ^a   Zhulina, Ekaterina ^a  

^a University of Pittsburgh   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADSORPTION; CELLS; CONFORMATIONS; INTERFACES (MATERIALS); PLASTIC COATINGS; SUBSTRATES; VIRUSES;

INTERACTION ENERGY; SCALING THEORY; STICKER CONCENTRATION;

COPOLYMERS;

EID: 0032497211     PISSN: 00249297     EISSN: None     Source Type: Journal    
DOI: 10.1021/ma980624d     Document Type: Article

References (31)

1. Napper, D. H. Polymeric Stabilization of Colloidal Dispersions; Academic Press: New York, 1983.
2. Stryer, L. Biochemistry; W. H. Freeman and Company: New York, 1988; p 869.
3. Wiley, D. C.; Skehel, J. J. Annu. Rev. Biochem. 1987, 56, 365.
4. Wharton, S. A.; Weis, W.; Skehel, J. J.; Wiley: D. The Influenza Viruses, Krug, R. M., Ed., Plenum Press: New York, 1989; p 153.
5. Spaltenstein, A.; Whitesides, G. M. J. Am. Chem. Soc. 1991, 113, 686.
6. Sigal, G. B.; Mammen, M.; Dahman, G.; Whitesides, G. M. J. Am. Chem. Soc. 1996, 118, 3789.
7. Mastrosovich, M. N.; Mochalova, L. U.; Marinina, V. P.; Byramova, N. E.; Bovin, N. V. FEBS Lett. 1990, 272, 209.
8. Roy, R.; Laferriere, C. A. Carbohydr. Res. 1988, 177, c1.
9. Mammen, M.; Choi, S.-K.; Whitesides, G. M. Angew. Chem., Int. Ed. Engl., in press.
10. The value of ∈ is on the order of 10kT for the binding of a SA group within a copolymer to the HA receptor. (Whitesides, G. M. Private Communication.)
11. Russell, W.; Saville, D. A.; Schowalter, W. R. Colloidal Dispersions; Cambridge University Press: Cambridge, England, 1989; p 134.
12. (a) Issaevitch, T. A.; Jasnow, D.; Balazs, A. C. J. Chem. Phys. 1993, 99, 8244 and references therein.
13. (b) Zhulina, E. B.; Skvortsov, A. M.; Birshtein, T. M. Polym. Sci. USSR 1981, 23, 304.
14. (c) Muthukumar, M. J. Chem. Phys. 1995, 103, 4723.
15. (d) Andelman, D.; Joanny, J.-F. Macromolecules 1991, 24, 6040.
16. (e) Srebnik, S.; Chakraborty, A. K.; Shakhnovich, E. I. Phys. Rev. Lett. 1996, 77, 3157.
17. This specific conformation is a rather arbitrary choice; it is not a necessary condition of the model. Any conformation in which the chains form extended loops of relatively uniform size is also appropriate in this theory.
18. Again, our choice of where to cut the loops is rather arbitrary. Within the framework of scaling theory, the cut can be made anywhere along the chain as long as the resulting fragments, or subchains, form extended tails of relatively uniform size.
19. (a) Skvortsov, A. M.; Gorbunov, A. A.; Parlushkov, V. A.; Zhulina, E. B.; Borisov, O. V.; Priamitsyn, V. A. Polym. Sci. USSR 1988, 30, 1706.
20. (b) We employ a mean-field approximation to describe the polymer coating. We use this approach in order to be consistent with our numerical SCF calculations. The use of a scaling model for the free energy will not lead to qualitative changes in the general picture.
21. Alexander, S. J. Phys. (Paris) 1977, 38, 983.
22. de Gennes, P.-G. J. Phys. (Paris) 1976, 37, 1443.
23. (a) Singh, C.; Pickett, G.; Balazs, A. C. Macromolecules 1996, 29, 7559.
24. (b) Pickett, G.; Balazs, A. C. Macromol. Symp. 1997, 121, 269.
25. Decreasing the local solvent quality might not, however, be practical for in vivo applications.
26. Fleer, G.; Cohen-Stuart, M. A.; Scheutjens, J. M. H. M.; Cosgrove, T. Vincent, B. Polymers at Interfaces; Chapman and Hall: London, 1993.
27. (a) Huang, K.; Balazs, A. C. Phys. Rev. Lett. 1991, 66, 620.
28. (b) Huang, K.; Balazs, A. C. Macromolecules 1993, 26, 4736.
29. (c) Israels, R.; Gersappe, D.; Fasolka, M.; Roberts, V. A.; Balazs, A. C. Macromolecules 1994, 27, 6679.
30. 2. The latter procedure corresponds to superimposing a larger grid on an area Σ of the sq lattice, where the distance between grid points is now equal to d, the spacing between the receptors. We are effectively multiplying the sq free energy by the total number of sites that belong to the larger grid.
31. Zagst, K. J.; Balazs, A. C.; Whitesides, G. M. In Proceedings of the Sixth National Conference on Undergraduate Research; Ed. Yearout, R. D., Ed.; University of North Carolina: Asheville, NC, 1992; Vol. 2, p 1201.