Effects of the GABA agonists baclofen and THIP on long-term compensation in hemilabyrinthectomised rats

Brain Research

Volumn 795, Issue 1-2, 1998, Pages 307-311

  Magnusson, Anna K ^a   Eriksson, Birgitta ^a   Tham, Richard ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Eye movement; GABA; Search coil; Vestibular compensation

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; BACLOFEN; GABOXADOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; EYE MOVEMENT; LABYRINTHECTOMY; NONHUMAN; PRIORITY JOURNAL; RAT; VESTIBULAR NUCLEUS;

ANIMALS; BACLOFEN; EAR, INNER; EYE MOVEMENTS; FUNCTIONAL LATERALITY; GABA AGONISTS; ISOXAZOLES; MAGNETICS; NYSTAGMUS, PATHOLOGIC; RATS; RATS, INBRED STRAINS; REFLEX, VESTIBULO-OCULAR;

EID: 0032496691     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00329-1     Document Type: Article

References (21)

1. L. Andersson, M. Ulfendahl, R. Tham, A method to study the effects of neurochemicals on long-term compensation after unilateral labyrinthectomy in rats, J. Neural Transpl. Plasticity 6 (1997) 105-113.
2. M. Anniko, J. Wersäll, Experimentally (atoxyl) induced ampullar degeneration and damage to the macule utriculi, Acta Otolaryngol. 83 (1977) 429-440.
3. E.A. Baarsma, H. Collewijn, Changes in compensatory eye movements after unilateral labyrinthectomy in the rabbit, Arch. OtoRhino-Laryngol. 211 (1975) 219-230.
4. C.L. Darlington, P.F. Smith, The recovery of static vestibular function following peripheral vestibular lesions in mammals: the intrinsic mechanism hypothesis, J. Vestibular Res. 6 (1996) 185-201.
5. C.L. Darlington, H. Flohr, P.F. Smith, Molecular mechanisms of brainstem plasticity. The vestibular compensation model, Mol. Neurobiol. 5 (1991) 355-368.
6. C. de Waele, M. Mühlethaler, P.P. Vidal, Neurochemistry of the central vestibular pathways, Brain Res. Rev. 20 (1995) 24-46.
7. S. du Lac, J.L. Raymond, T.J. Sejnowski, S.G. Lisberger, Learning and memory in the vestibulo-ocular reflex, Annu. Rev. Neurosci. 18 (1995) 409-441.
8. M.B. Dutia, A.R. Johnston, D.S. McQueen, Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA, Exp. Brain Res. 88 (1992) 466-472.
9. H. Flohr, H.U. Luneburg, Role of NMDA receptors in lesion-induced plasticity, Arch. Ital. Biol. 131 (1993) 173-190.
10. S. Grassi, G. Della Torre, G. Capocchi, M. Zampolini, V.E. Pettorossi, The role of GABA in NMDA-dependent long term depression (LTD) of rat medial vestibular nuclei, Brain Res. 699 (1995) 183-191.
11. H.J. Kasper, B.J.M. Hess, N. Dieringer, A precise and inexpensive magnetic search coil system for measuring eye and head movements in small laboratory animals, J. Neurosci. 19 (1987) 115-124.
12. B receptors, Pharmacol. Ther. 67 (1995) 187-246.
13. B receptors and the effects of baclofen in the mammalian central nervous system, Prog. Neurobiol. 46 (1995) 423-462.
14. B receptors, Int. Rev. Neurobiol. 36 (1994) 97-223.
15. M. Niklasson, R. Tham, B. Larsby, B. Eriksson, Effects of toluene, styrene, trichloroethylene and trichloroethane on the vestibulo- and opto-oculo motor system in rats, Neurotoxicol. Teratol. 15 (1993) 327-334.
16. B activation and inhibition on vestibulo-ocular and optokinetic responses in the pigmented rat, Brain Res. 649 (1994) 151-158.
17. B.W. Peterson, G.A. Kinney, K.J. Quinn, N.T. Slater, Potential mechanisms of plastic adaptive changes in the vestibulo-ocular reflex, Ann. New York Acad. Sci. 781 (1996) 499-512.
18. P.F. Smith, I.S. Curthoys, Mechanisms of recovery following unilateral labyrinthectomy: a review, Brain Res. Rev. 14 (1989) 155-180.
19. P.F. Smith, C.L. Darlington, Neurochemical mechanisms of recovery from peripheral vestibular lesions (vestibular compensation), Brain Res. 16 (1991) 117-133.
20. R. Tham, B. Larsby, B. Eriksson, M. Niklasson, Effect of toluene on the vestibulo- and opto-oculomotor system in rats, pretreated with GABA-ergic drugs, Neurotoxicol. Teratol. 12 (1990) 307-311.
21. N. Vibert, C. de Waele, M. Serafin, A. Babalian, M. Mühlethaler, P.P. Vidai, The vestibular system as a model of sensorimotor transformations. A combined in vitro and in vivo approach to study the cellular mechanisms of gaze and posture stabilization in mammals, Prog. Neurobiol. 51 (1997) 243-286.