Characterization of specific binding of [125I]L-762,459, a selective α(1A)-adrenoceptor radioligand to rat and human tissues

European Journal of Pharmacology

Volumn 348, Issue 2-3, 1998, Pages 287-295

  O'Malley, Stacey S ^a   Chen, Tsing B ^a   Francis, Barbara E ^a   Gibson, Raymond E ^a   Burns, H Donald ^a   DiSalvo, Jerry ^b   Bayne, Marvin L ^b   Wetzel, John M ^c   Nagarathnam, Dhanapalan ^c   Marzabadi, Mohammad ^c   Gluchowski, Charles ^c   Chang, Raymond S L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Dept of Molec Pharmacol and B ^*  (United States)

^c H LUNDBECK A S   (Denmark)

Author keywords

(1A) Adrenoceptor; Adrenoceptor, subtype; Binding; Radioligand

Indexed keywords

2 (2 AMINOETHOXYMETHYL) 6 ETHYL 1,4 DIHYDRO 4 (4 NITROPHENYL) 3,5 PYRIDINEDICARBOXYLIC ACID 5 AMIDE 3 [3 (4,4 DIPHENYL 1 PIPERIDINYL)PROPYL]AMIDE; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; IODINE 125; L 762459; NIGULDIPINE; PHENTOLAMINE; PRAZOSIN; RADIOLIGAND; TERAZOSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HEART; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; RAT; TISSUE DISTRIBUTION; VAS DEFERENS;

ADRENERGIC ALPHA-ANTAGONISTS; AMIDINES; ANIMALS; BINDING, COMPETITIVE; CEREBRAL CORTEX; DIHYDROPYRIDINES; HIPPOCAMPUS; HUMANS; IODINE RADIOISOTOPES; KIDNEY; MALE; MYOCARDIUM; PHENTOLAMINE; PIPERIDINES; PRAZOSIN; PROSTATE; RADIOLIGAND ASSAY; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP; VAS DEFERENS;

EID: 0032496076     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00149-6     Document Type: Article

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