High-performance liquid chromatographic analysis of staurosporine in vivo. Its translocation and pharmacokinetics in rats

Journal of Chromatography B: Biomedical Applications

Volumn 712, Issue 1-2, 1998, Pages 211-224

  Gurley, L R ^a   Umbarger, K O ^a   Kim, J M ^a   Bradbury, E M ^a   Lehnert, B E ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

Staurosporine

Indexed keywords

PROTEIN KINASE INHIBITOR; STAUROSPORINE;

ANIMAL EXPERIMENT; ARTICLE; DRUG ADSORPTION; DRUG DETERMINATION; DRUG HALF LIFE; DRUG SCREENING; DRUG TRANSPORT; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; AUTOMATIC DATA PROCESSING; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ERYTHROCYTES; INJECTIONS, INTRAVENOUS; MALE; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; RATS; RATS, INBRED F344; SPECTROPHOTOMETRY, ULTRAVIOLET; STAUROSPORINE; TISSUE DISTRIBUTION;

EID: 0032493856     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(98)00077-2     Document Type: Article

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