Controlled design of resolutions. Prediction of the efficiency of resolutions based on samples of arbitrary composition

Tetrahedron Asymmetry

Volumn 9, Issue 15, 1998, Pages 2745-2753

  Ebbers, Eelco ^a   Ariaans, Gerry J A ^a   Zwanenburg, Binne ^a   Bruggink, Alle ^a,b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b Chemferm   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; ETHYLAMINE; HEXANE; HYDRATROPIC ACID; IBUPROFEN; MANDELIC ACID; TRIFLUOROACETIC ACID;

ARTICLE; CHEMICAL COMPOSITION; CHIRALITY; CRYSTALLIZATION; DIASTEREOISOMER; DIFFERENTIAL SCANNING CALORIMETRY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PREDICTION; PRIORITY JOURNAL; RACEMIC MIXTURE; SYNTHESIS; THERMOGRAPHY;

EID: 0032493842     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00280-8     Document Type: Article

References (22)

1. (a) Van der Haest, A. D.; Wijnberg, H.; Leusen, F. J. J.; Bruggink, A. Recl. Trav. Chim. Pays-Bas 1990, 109, 523.
2. (b) Leusen, F. J. J. Rationalization of Racemate Resolution: A Molecular Modelling Study; Ph.D. Thesis: University of Nijmegen, The Netherlands, 1993.
3. (c) Van der Haest, A. D. Classical Resolutions; Design of Resolving Agents and Studies of Diastereomeric Salts; Ph.D. Thesis: University of Groningen, The Netherlands, 1992.
4. Jacques, J.; Collet, A.; Wilen, S. H. "Enantiomers, Racemates and Resolution"; John Wiley & Sons, New York, 1981, pp. 290-305.
5. Fogassy, E.; Faigl, F.; Darvas, F.; Acs, M.; Toke, L. Tetrahedron Lett. 1980, 21, 2841.
6. Leclercq, M.; Jacques, J. Bull. Soc. Chim. Fr. 1972, 2052.
7. Kozma, D.; Pokol, G.; Acs, M. J. Chem. Soc. Perkin Trans. 2 1992, 435.
8. Brown, M. E. "Introduction to Thermal Analysis", Chapman and Hall, London, 1988, pp. 23-49.
9. Fitting of peaks was performed using PeakFit™© version 4 for Win32 (Jandel Scientific Software). Pearson IV peaks were used as peak description.
10. Prigogine, I.; Defay, R. "Chemical Thermodynamics", Longmans, London, 1954. Chapter 22.
11. Using, for example, a spreadsheet program such as Excel.
12. (a) Takagi, S.; Fujiskiro, R.; Amaya, R. Chemm. Comm. 1968, 480.
13. (b) Guetté, J. P.; Boucherot, D.; Horeau, A. Tetrahedron Lett. 1973, 465.
14. (c) Horeau, A.; Guetté, J. P. Tetrahedron 1974, 30, 1923.
15. Ebbers, E. J. Racemization and Asymmetric Transformation of α-Substituted Carboxylic Acids; Ph.D. Thesis, University of Nijmegen, 1997. Section 5.1.
16. Leclercq, L.; Jacques, J. Bull. Soc. Chim. France 1975, 2052.
17. Jacques, J.; Collet, A.; Wilen, S. H. "Enantiomers, Racemates and Resolution"; John Wiley & Sons, New York, 1981, Section 5.1.10.
18. Ibid. Section 5.3.
19. (a) De Diego, H. L. Acta Chem. Scand. 1995, 49, 459.
20. (b) Larsen, S.; De Diego, H. L. Models in Chemistry 1995, 132, 441.
21. Ebbers, E. J.; Plum, B. J. M.; Ariaans, G. J. A.; Kaptein, B.; Broxterman, Q. B.; Bruggink, A.; Zwanenburg, B. Tetrahedron: Asymmetry 1997, 8, 4047.
22. Jacques, J.; Collet, A.; Wilen, S. H. "Enantiomers, Racemates and Resolution"; John Wiley & Sons, New York, 1981, pp. 35-36.