Synthesis and biological activity of lactones en route to Altohyrtin A

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 13, 1998, Pages 1635-1638

  Hermitage, Stephen A ^a   Murphy, Alison ^a   Roberts, Stanley M ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LACTONE DERIVATIVE; SPONGISTATIN 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; ETHERS, CYCLIC; HUMANS; LACTONES; MACROLIDES; TUMOR CELLS, CULTURED;

EID: 0032493337     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00268-6     Document Type: Article

References (7)

1. 1. Hermitage, S.A., Nielson, P., Murphy, A., Roberts, S.M., Tetrahedron, in press.
2. 2. Kobayashi, M., Aoki, S., Kitagawa, I., Tetrahedron Lett., 1994, 35, 1243.
3. 3. Pettit, G.R., Cichacz, Z.A., Herald, C.L., Gao, F., Boyd, M.R., Schmidt, J.N., Hamel, E., Bai, R., J. Chem. Soc., Chem. Comm., 1994, 1605.
4. 4. We thank Professor G.R. Pettit for communication of these results from his laboratory at the Arizona State University.
5. 5. Bruzik, K.S., Tsai, M-D., J. Am. Chem. Soc., 1992, 114, 6361.
6. 6. Swern, D., Omura, K., Tetrahedron, 1978, 34, 1651.
7. ++H, 15%).